Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Monica M. Santisteban"'
Autor:
Jasenka Zubcevic, Monica M. Santisteban, Pablo D. Perez, Rebeca Arocha, Helmut Hiller, Wendi L. Malphurs, Luis M. Colon-Perez, Ravindra K. Sharma, Annette de Kloet, Eric G. Krause, Marcelo Febo, Mohan K. Raizada
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Activation of autonomic neural pathways by chronic hypertensive stimuli plays a significant role in pathogenesis of hypertension. Here, we proposed that even a single acute hypertensive stimulus will activate neural and immune pathways that may be im
Externí odkaz:
https://doaj.org/article/6a487f8ead6045099af123507ed03b4f
Autor:
Monica M. Santisteban, Giuseppe Faraco, David Brea Lopez, Gang Wang, Melissa Sobanko, Rose Sciortino, Gianfranco Racchumi, Ari Waisman, Josef Anrather, Costantino Iadecola
Hypertension, a disease afflicting over one billion individuals worldwide, is a leading cause of cognitive impairment, the mechanisms of which remain poorly understood. In a mouse model of hypertension involving brain angiotensin signaling, we found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6735aeb0438c39798bd5bef82d9cde4d
https://doi.org/10.1101/2022.09.05.506398
https://doi.org/10.1101/2022.09.05.506398
Autor:
Samantha M Schaeffer, Monica M Santisteban, Giuseppe Faraco, Lidia Garcia-bonilla, Josef Anrather, Costantino Iadecola
Publikováno v:
Hypertension. 79
Hypertension (HTN) disrupts vital neurovascular control mechanisms, thereby increasing the brain’s susceptibility to vascular insufficiency, white matter lesions, and cognitive impairment. Yet, the distinct vascular, neuronal, and glial cell types
Autor:
Monica M Santisteban, Lidia Glodzik
Publikováno v:
Hypertension. 78:644-646
Elevated bone marrow sympathetic drive precedes systemic inflammation in angiotensin II hypertension
Autor:
Mohan K. Raizada, Riley Larkin, Jasenka Zubcevic, Douglas R. Miller, David M. Baekey, Natalie M. Geis, Habibeh Khoshbouei, Ty Redler, Niousha Ahmari, Heather Denson, Monica M Santisteban
Publikováno v:
Am J Physiol Heart Circ Physiol
Increased sympathetic nervous system activity is a hallmark of hypertension (HTN), and it is implicated in altered immune system responses in its pathophysiology. However, the precise mechanisms of neural-immune interaction in HTN remain elusive. We
Autor:
Giuseppe Faraco, Sung Ji Ahn, Josef Anrather, Jakob Körbelin, Costantino Iadecola, Carrie Poon, Samantha Schaeffer, Gianfranco Racchumi, Steven G. Segarra, Lidia Garcia-Bonilla, Monica M Santisteban, Diane A. Lane
Publikováno v:
Hypertension
Hypertension is a leading cause of stroke and dementia, effects attributed to disrupting delivery of blood flow to the brain. Hypertension also alters the blood-brain barrier (BBB), a critical component of brain health. Although endothelial cells are
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 38:2112-2128
Dementia is growing at an alarming rate worldwide. Although Alzheimer disease is the leading cause, over 50% of individuals diagnosed with Alzheimer disease have vascular lesions at autopsy. There has been an increasing appreciation of the pathogenic
Autor:
Lidia Garcia-Bonilla, Michelle Murphy, Giuseppe Faraco, Gang Wang, Kenzo Koizumi, Joseph Anrather, Henning U. Voss, David Brea, Monica M Santisteban, Haejoo Chang, Izaskun Buendia, Yukio Sugiyama, Steven G. Segarra, Gianfranco Racchumi, Costantino Iadecola
Publikováno v:
Nature Neuroscience. 21:240-249
A diet rich in salt is linked to an increased risk of cerebrovascular diseases and dementia, but it remains unclear how dietary salt harms the brain. We report that, in mice, excess dietary salt suppresses resting cerebral blood flow and endothelial
Autor:
Monica M Santisteban, Carl J. Pepine, Mohan K. Raizada, Richard D. Johnson, Andres Rubiano, Colleen T. Cole-Jeffrey, Chelsey S. Simmons, Daniel C. Stewart, Tao Yang, Gilberto O Lobaton, Yanfei Qi, Jasenka Zubcevic, Fernando L Garcia-Pereira, Seungbum Kim, Vinayak Shenoy
Publikováno v:
Circulation Research. 120:312-323
Rationale: Sympathetic nervous system control of inflammation plays a central role in hypertension. The gut receives significant sympathetic innervation, is densely populated with a diverse microbial ecosystem, and contains immune cells that greatly
Autor:
Giuseppe Faraco, Josef Anrather, Monica M Santisteban, Costantino Iadecola, Lidia Garcia-Bonilla, Carrie Poon, Samantha Schaeffer, Diane A. Lane, Virginia Cipollini, Ziasmin Shahanoor, Gianfranco Racchumi, Steven G. Segarra, Sung Ji Ahn
Publikováno v:
Hypertension. 74
The blood-brain barrier (BBB) controls the molecular exchange between blood and brain and is critical for maintaining brain health. Although hypertension (HTN) is well known to disrupt the BBB, the underlying cellular bases and the susceptible cerebr