Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Monica M. Purmalek"'
Autor:
Heather L. Teague, PhD, Nevin J. Varghese, BS, Lam C. Tsoi, PhD, Amit K. Dey, MD, Michael S. Garshick, MD, Joanna I. Silverman, BA, Yvonne Baumer, PhD, Charlotte L. Harrington, BA, Erin Stempinski, MS, Youssef A. Elnabawi, BS, Pradeep K. Dagur, PhD, Kairong Cui, PhD, Ilker Tunc, PhD, Fayaz Seifuddin, MSc, Aditya A. Joshi, MD, Elena Stansky, BS, Monica M. Purmalek, BS, Justin A. Rodante, PA, Andrew Keel, DNP, Tarek Z. Aridi, BS, Carmelo Carmona-Rivera, PhD, Gregory E. Sanda, BS, Marcus Y. Chen, MD, Mehdi Pirooznia, MD, PhD, J. Philip McCoy, Jr., PhD, Joel M. Gelfand, MD, Keji Zhao, PhD, Johann E. Gudjonsson, MD, PhD, Martin P. Playford, PhD, Mariana J. Kaplan, MD, Jeffrey S. Berger, MD, Nehal N. Mehta, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 1-14 (2019)
Summary: Psoriasis is an inflammatory skin disease associated with increased cardiovascular risk and serves as a reliable model to study inflammatory atherogenesis. Because neutrophils are implicated in atherosclerosis development, this study reports
Externí odkaz:
https://doaj.org/article/58c2052d89974c20b205441c9749fd1d
Autor:
Monica M Purmalek, Zachary A Kopelman, Jeffery D Griffis, Krista M Mehlhaff, Veronica M Gonzalez-Brown
Publikováno v:
Military medicine.
Newly diagnosed malignancy during pregnancy is rare affecting approximately 1 in 1,000 pregnancies. Breast followed by hematologic malignancies are most common. Hodgkin’s lymphoma (HL) is a lymphoid neoplasm which can present with lymphadenopathy o
Autor:
Tarek Z Aridi, Ilker Tunc, Lam C. Tsoi, Elena Stansky, Mehdi Pirooznia, Joanna I Silverman, Marcus Y. Chen, Aditya A. Joshi, Kairong Cui, J. Philip McCoy, Joel M. Gelfand, Erin Stempinski, Charlotte L. Harrington, Martin P. Playford, Heather L. Teague, Andrew Keel, Nehal N. Mehta, Keji Zhao, Pradeep K. Dagur, Carmelo Carmona-Rivera, Justin A. Rodante, Gregory E. Sanda, Nevin J. Varghese, Johann E. Gudjonsson, Youssef A. Elnabawi, Jeffrey S. Berger, Michael S. Garshick, Mariana J. Kaplan, Amit K. Dey, Monica M. Purmalek, Yvonne Baumer, Fayaz Seifuddin
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 1-14 (2019)
JACC: Basic to Translational Science
JACC: Basic to Translational Science
Visual Abstract
Highlights • LDGs are a subset of neutrophils that were elevated in psoriasis and associated with the severity of disease. • In psoriasis, LDGs associated with noncalcified coronary plaque burden beyond cardiovascular risk fa
Highlights • LDGs are a subset of neutrophils that were elevated in psoriasis and associated with the severity of disease. • In psoriasis, LDGs associated with noncalcified coronary plaque burden beyond cardiovascular risk fa
Autor:
V. Michael Holers, William H. Robinson, Michael H. Weisman, Emily Bowers, M. Kristen Demoruelle, Nickie L Seto, Lauren J. Lahey, Jill M. Norris, Jeremy Sokolove, Mariana J. Kaplan, Monica M. Purmalek, Kevin D. Deane
Publikováno v:
Arthritis & Rheumatology. 70:516-527
Objective The location and mechanisms involved in the initial generation of autoantibodies to citrullinated and noncitrullinated proteins/peptides during the natural history of rheumatoid arthritis (RA) development is incompletely understood. This st
Autor:
Rachel A. Idol, Ning Yu, Mariana J. Kaplan, Lizet J. Perez-Zapata, Monica M. Purmalek, Chaim O. Jacob, Emilia Alina Barbu, Mary C. Dinauer, Jeanette T. Pingel, Dae-Goon Yoo
Publikováno v:
Arthritis & Rheumatology. 69:1647-1660
Objective. We have previously established that NCF2 (Neutrophil cytosolic factor 2) is a lupus predisposing gene and identified lupus patients with point mutations that are predicted to cause reduced NADPH oxidase activity. This study was undertaken
Autor:
Katherine Pak, José J. Torres-Ruíz, Diana Gómez-Martín, Iago Pinal-Fernandez, José C. Milisenda, Frederick W. Miller, Yuji Hosono, Nickie L Seto, Olivier Benveniste, Adam I. Schiffenbauer, Lisa Christopher-Stine, Lisa G. Rider, Alexander M. Gorbach, Josep M. Grau-Junyent, Prateek Gowda, Ingrid E. Lundberg, Cátia Fernandes-Cerqueira, Monica M. Purmalek, Albert Selva-O'Callaghan, J. Michelle Kahlenberg, Nathan Arnett, Mariana J. Kaplan, Andrew L. Mammen, Carmelo Carmona-Rivera
Publikováno v:
JCI insight. 5(3)
Idiopathic inflammatory myopathies (IIM) are characterized by muscle inflammation and weakness, myositis-specific autoantibodies (MSAs), and extramuscular organ damage. The role of neutrophil dysregulation and neutrophil extracellular traps (NETs) in
Autor:
Keith B. Elkon, Mariana J. Kaplan, Luz P. Blanco, Jeffrey A. Ledbetter, Monica M. Purmalek, Suk See De Ravin, Christian Lood, Carolyne K. Smith, Harry L. Malech, Carmelo Carmona-Rivera
Publikováno v:
Nature medicine
Neutrophil extracellular traps (NETs) are implicated in autoimmunity, but how they are generated and their roles in sterile inflammation remain unclear. Ribonucleoprotein immune complexes (RNP ICs), inducers of NETosis, require mitochondrial reactive
Autor:
Alice Fike, Maureen Sampson, Nehal N. Mehta, Monica M. Purmalek, Philip M. Carlucci, Zerai Manna, Jonathan H. Chung, Taufiq Salahuddin, Yenealem Temesgen-Oyelakin, Mariana J. Kaplan, Amit K. Dey, Marcus Y. Chen, Alan T. Remaley, Simantini Sakhardande, Sarthak Gupta, Michael Davis, Sarfaraz Hasni, Joseph B Lerman
Publikováno v:
Clinical Sciences.
Background Subjects with Systemic Lupus Erythematosus (SLE) display an increased risk of atherosclerotic cardiovascular disease (CVD) that is not explained by Framingham Risk. This study sought to investigate the utility of nuclear magnetic resonance
Autor:
Joseph B Lerman, Hong-Wei Sun, Faiza Naz, Zerai Manna, Monica M. Purmalek, Yenealem Temesgen-Oyelakin, Martin P. Playford, Gustavo Gutierrez-Cruz, Philip M. Carlucci, Aditya A. Joshi, Heather L. Teague, Alice Fike, Peter C. Grayson, Pragnesh Mistry, Taufiq Salahuddin, Mohammad Naqi, Balaji Natarajan, Mariana J. Kaplan, Amit K. Dey, Marcus Y. Chen, Stefania Dell'Orso, Jonathan H. Chung, Nehal N. Mehta, Simantini Sakhardande, Sarthak Gupta, Wanxia L. Tsai, Sarfaraz Hasni, Michael Davis
Publikováno v:
JCI Insight. 3
BACKGROUND. Systemic lupus erythematosus (SLE) is associated with enhanced risk of atherosclerotic cardiovascular disease not explained by Framingham risk score (FRS). Immune dysregulation associated to a distinct subset of lupus proinflammatory neut
Autor:
Yuko Okamoto, Monica M. Purmalek, Kevin D. Deane, Lindsay B. Kelmenson, Jill M. Norris, Heather M. Rothfuss, Michael Mahler, Chelsie Fleischer, Michael H. Weisman, Mariana J. Kaplan, M. Kristen Demoruelle, Nickie L Seto, Joshua J. Solomon, Courtney Anderson, Linh Ho, Marie L. Feser, V. Michael Holers, Kylie K. Harrall, Mark C. Parish, Brian D. Cherrington, Aryeh Fischer
Objectives: Studies suggest that rheumatoid arthritis (RA)-related autoimmunity is initiated at a mucosal site. However, the factors associated with the mucosal generation of this autoimmunity are unknown, especially in individuals who are at-risk fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01dd0950fd10e2105987a912ac70d090
https://europepmc.org/articles/PMC5449213/
https://europepmc.org/articles/PMC5449213/