Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Monica M. Holmes"'
Publikováno v:
International Journal of Peptide and Protein Research. 35:249-257
A convergent synthesis of the peptide [1-(β-mercapto-β,β-cyclopentamethylenepropionic acid)-2-(O-ethyl-d-tyrosine)-4-valine-9-desglycine]arginine vasopressin (1), based on the classical solution phase method, was developed. The molecule is assembl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d62a4286a3974f72685ec2d2e4e8872
https://doi.org/10.1111/j.1399-3011.1990.tb00945.x
https://doi.org/10.1111/j.1399-3011.1990.tb00945.x
Publikováno v:
Synthetic Communications. 26:593-601
A regioselective mono-benzylation of the 4-hydroxyl group of 2,4-dihydroxybenzaldehyde (2) to produce 1 under extremely mild basic conditions (NaHCO3 or KF) has been developed. This approach gives improved regioselectivity relative to earlier methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcdaca38b9d91e818a53b2516a789d60
https://doi.org/10.1080/00397919608003653
https://doi.org/10.1080/00397919608003653
Autor:
Joseph R. Flisak, Alvydas Alfonsas Jarmas, Lawrence Snyder, Kerry Gombatz, Vance J. Novack, Wilford Mendelson, Ivan Lantos, James J. Remich, Monica M. Holmes
Publikováno v:
The Journal of Organic Chemistry. 58:6247-6254
A highly efficient and enantioselective (>99.5% ee) synthesis of the title compound has been accomplished. Key steps include (1) epoxidation of unsaturated ketone 7 in the presence of a polyamino acid to afford compound 8 in >95 ee, (2) regioselectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb26daba5f6d9f62168a9e6b95f5491d
https://doi.org/10.1021/jo00075a019
https://doi.org/10.1021/jo00075a019
Publikováno v:
ChemInform. 27
A regioselective mono-benzylation of the 4-hydroxyl group of 2,4-dihydroxybenzaldehyde (2) to produce 1 under extremely mild basic conditions (NaHCO3 or KF) has been developed. This approach gives improved regioselectivity relative to earlier methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb52f336ffff753cc8521c3f8dad7dfc
https://doi.org/10.1002/chin.199624117
https://doi.org/10.1002/chin.199624117
Publikováno v:
The Journal of Organic Chemistry. 54:2490-2492
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02a1027d3d5f92e79e6eccca170a4f56
https://doi.org/10.1021/jo00271a057
https://doi.org/10.1021/jo00271a057