Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Monica M. Fahrenholtz"'
Characterization of Dermal Fibroblasts as a Cell Source for Pediatric Tissue Engineered Heart Valves
Autor:
Monica M. Fahrenholtz, Huiwen Liu, Debra L. Kearney, Lalita Wadhwa, Charles D. Fraser, K. Jane Grande-Allen
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 1, Iss 2, Pp 146-162 (2014)
There is continued debate regarding the appropriate cell type to replace valvular interstitial cells (VICs) in tissue engineered heart valves (TEHVs), particularly for pediatric patients. In this work, neonatal human dermal fibroblasts (nhDFFs) were
Externí odkaz:
https://doaj.org/article/ccd0cfb163d34d2e907d2e286072cee9
Autor:
Walker D. Short, Umang M. Parikh, Natalie Templeman, Oluyinka O. Olutoye, Alexander Blum, Daniel Colchado, Benjamin Padon, Aditya Kaul, Hui Li, Hima V. Vangapandu, Olivia S. Jung, Pranav Bommekal, Phillip Kogan, Monica M. Fahrenholtz, Cristian Coarfa, Swathi Balaji
ObjectiveFetal regenerative wound healing is characterized by hyaluronan(HA)-rich microenvironment and fibroblasts that produce pericellular matrices(PCM) abundant in high molecular weight HA. Recent studies showed that while small wounds in fetal sk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ee5b938242a4e5cbe4c3b7fdee1c66d
https://doi.org/10.1101/2020.09.30.319749
https://doi.org/10.1101/2020.09.30.319749
Autor:
Bartley J. Gill, Jonathon D. Roybal, Samir M. Hanash, Brandi N. Baird, Yulong Chen, Li Sun, Young Ho Ahn, Ignacio I. Wistuba, Edwin Roger Parra Cuentas, Xin Liu, Chad J. Creighton, Mary E. Dickinson, Jennifer L. West, K. Jane Grande-Allen, Min P. Kim, Masahiko Terajima, John Hicks, Jaime Rodriguez, Mark J. Schliekelman, Tegy J. Vadakkan, Jonathan M. Kurie, Monica M. Fahrenholtz, Mitsuo Yamauchi, Daniela Pankova, Don L. Gibbons
Publikováno v:
Molecular Cancer Research. 14:287-295
Intratumoral collagen cross-links heighten stromal stiffness and stimulate tumor cell invasion, but it is unclear how collagen cross-linking is regulated in epithelial tumors. To address this question, we used KrasLA1 mice, which develop lung adenoca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16ee3c809eccf2b37084dd7bf931184f
https://doi.org/10.1158/1541-7786.mcr-15-0307
https://doi.org/10.1158/1541-7786.mcr-15-0307
Autor:
K. Jane Grande-Allen, Elizabeth H. Stephens, Tomasz A. Timek, George T. Daughters, D. Craig Miller, Joyce J. Kuo, Neil B. Ingels, Monica M. Fahrenholtz, Patrick S. Connell, Aaron M. Patton
Publikováno v:
Cardiovascular Engineering and Technology. 6:151-159
Regional heterogeneity in mitral annular contraction, which is generally ascribed to the fibrous vs. muscular annular composition, ensures proper leaflet motion and timing of coaptation. It is unknown whether the fibroblast-like cells in the annulus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82b64ea2dde9ef59a7c36bf68bbe875
https://doi.org/10.1007/s13239-014-0209-3
https://doi.org/10.1007/s13239-014-0209-3
Publikováno v:
Acta Biomaterialia. 9:4906-4915
The use of biodegradable beta-tricalcium phosphate (β-TCP) scaffolds holds great promise for bone tissue engineering. However, the effects of β-TCP on bone and endothelial cells are not fully understood. This study aimed to investigate cell prolife
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::355ba4d3ac2fd3c092f446d4aef108e6
https://doi.org/10.1016/j.actbio.2012.08.008
https://doi.org/10.1016/j.actbio.2012.08.008
Autor:
Pan Tong, C. A. Wanna, K. J. Grande-Allen, Pamela Villalobos, David H. Peng, Barbara Mino, Naohiro Uraoka, Ignacio I. Wistuba, Chad J. Creighton, Richard I Han, Jaime Rodriguez Canales, J. Wang, Carmen Behrens, Don L. Gibbons, Lauren Averett Byers, Monica M. Fahrenholtz, C. Ungewiss
Publikováno v:
Oncogene
Lung cancer is the leading cause of cancer-related deaths, primarily due to distant metastatic disease. Metastatic lung cancer cells can undergo an epithelial-to-mesenchymal transition (EMT) regulated by various transcription factors, including a dou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed22f81d9cdaee3ef0daf1faaee1cd04
https://pubmed.ncbi.nlm.nih.gov/27694892
https://pubmed.ncbi.nlm.nih.gov/27694892
Publikováno v:
Nano Letters. 11:1270-1275
Transmission electron microscopy (TEM) of hygroscopic, permeable, and electron-absorbing biological cells has been an important challenge due to the volumetric shrinkage, electrostatic charging, and structural degradation of cells under high vacuum a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84d9433247eeafd40aba11c06da174a5
https://doi.org/10.1021/nl104292k
https://doi.org/10.1021/nl104292k
Publikováno v:
Acta biomaterialia. 26
Current bioprosthetic valve replacements (BPVs) are susceptible to myriad complications, including calcification and thrombosis; however, recent research has explored surface modifications to encourage re-endothelialization of the tissue, preventing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02f16772019598b8ede46503979deaa6
https://pubmed.ncbi.nlm.nih.gov/26296937
https://pubmed.ncbi.nlm.nih.gov/26296937
Autor:
Elizabeth H. Stephens, Neil B. Ingels, Aaron M. Patton, Patrick S. Connell, George T. Daughters, K. Jane Grande-Allen, Tomasz A. Timek, Monica M. Fahrenholtz, D. Craig Miller, Joyce J. Kuo
To determine how extracellular matrix and contractile valvular cells contribute to the heterogeneous motion and strain across the mitral valve (MV) during the cardiac cycle, regional MV material properties, matrix composition, matrix turnover, and ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8cb0c437f453da282fb20fd19cfd4ea
https://europepmc.org/articles/PMC4512834/
https://europepmc.org/articles/PMC4512834/
Autor:
Fahrenholtz M; Department of Surgery, Texas Children's Hospital and Baylor College of Medicine, Houston, TX., Salvati DR; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA., Scott LB; Sponsored Programs Office, Baylor College of Medicine, Houston, TX., Goldstein AM; Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA., Keswani SG; Department of Surgery, Texas Children's Hospital and Baylor College of Medicine, Houston, TX. Electronic address: keswani@bcm.edu.
Publikováno v:
Surgery [Surgery] 2022 Feb; Vol. 171 (2), pp. 342-347. Date of Electronic Publication: 2021 Jun 29.