Zobrazeno 1 - 2
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pro vyhledávání: '"Monica Lopez-Islas"'
Publikováno v:
Protein Science. 25:1129-1137
By virtue of their size, functional group diversity, and complex structure, proteins can often recognize and modulate disease-relevant macromolecules that present a challenge to small-molecule reagents. Additionally, high-throughput screening and evo
Autor:
Sandra M. DePorter, Virginia J. Bruce, Brian R. McNaughton, Irene Lui, Melissa A. Gray, Monica Lopez-Islas
Publikováno v:
Mol. BioSyst.. 10:18-23
Alanine scanning mutagenesis of a recently reported prostate cancer cell-selective Protein Transduction Domain (PTD) was used to assess the specific contribution each residue plays in cell uptake efficiency and cell-selectivity. These studies resulte