Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Monica Loi"'
Autor:
Monica Loi, Anne Müller, Karin Steinbach, Jennifer Niven, Rosa Barreira da Silva, Petra Paul, Laure-Anne Ligeon, Assunta Caruso, Randy A. Albrecht, Andrea C. Becker, Nicolas Annaheim, Heike Nowag, Jörn Dengjel, Adolfo García-Sastre, Doron Merkler, Christian Münz, Monique Gannagé
Publikováno v:
Cell Reports, Vol 15, Iss 5, Pp 1076-1087 (2016)
The macroautophagy machinery has been implicated in MHC class II restricted antigen presentation. Here, we report that this machinery assists in the internalization of MHC class I molecules. In the absence of the autophagy factors Atg5 and Atg7, MHC
Externí odkaz:
https://doaj.org/article/0ffbe6a60139450b93e51dbd9fcd7dc9
Autor:
Mirco Ponzoni, Vito Pistoia, Domenico Ribatti, Beatrice Nico, Michele Cilli, Federica Piccardi, Luis J.V. Galietta, Monica Loi, Annalisa Pezzolo, Chiara Brignole, Danilo Marimpietri, Fabio Pastorino, Roberta Carosio, Daniela Di Paolo, Gabriella Pagnan
Supplementary Data from The Combined Therapeutic Effects of Bortezomib and Fenretinide on Neuroblastoma Cells Involve Endoplasmic Reticulum Stress Response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72d148e049274ca37297071726ad7739
https://doi.org/10.1158/1078-0432.22440579
https://doi.org/10.1158/1078-0432.22440579
Autor:
Mirco Ponzoni, Jinzi J. Wu, Theresa M. Allen, Angelo Corti, Renato Longhi, Seema V. Garde, Eugene A. Lepekhin, Michele Cilli, Gabriella Pagnan, Danilo Marimpietri, Monica Loi, Chiara Brignole, Carlo E. Neumaier, Gabriella Baio, Antonio Daga, Domenico Ribatti, Beatrice Nico, Federica Piccardi, Daniela Di Paolo, Fabio Pastorino
Purpose:In vivo evaluation of good manufacturing practice-grade targeted liposomal doxorubicin (TVT-DOX), bound to a CD13 isoform expressed on the vasculature of solid tumors, in human tumor xenografts of neuroblastoma, ovarian cancer, and lung cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93523f3ed420bb0a955ace4b9fb41f54
https://doi.org/10.1158/1078-0432.c.6516859.v1
https://doi.org/10.1158/1078-0432.c.6516859.v1
Autor:
Mirco Ponzoni, Vito Pistoia, Domenico Ribatti, Beatrice Nico, Michele Cilli, Federica Piccardi, Luis J.V. Galietta, Monica Loi, Annalisa Pezzolo, Chiara Brignole, Danilo Marimpietri, Fabio Pastorino, Roberta Carosio, Daniela Di Paolo, Gabriella Pagnan
Purpose: The proteasome inhibitor bortezomib inhibited cell growth and angiogenesis in neuroblastoma. Bortezomib has been shown to induce synergistic activity when combined with other antineoplastic agents. Here we have investigated the antitumor act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b323b035a19d2853149a09e0fe2532b
https://doi.org/10.1158/1078-0432.c.6517884.v1
https://doi.org/10.1158/1078-0432.c.6517884.v1
Autor:
Mirco Ponzoni, Vito Pistoia, Claudio Gambini, Riccardo Haupt, Giovanni Erminio, Irene Caffa, Monica Loi, Gabriella Pagnan, Alessia Zorzoli, Fabio Pastorino, Fabio Morandi, Patrizia Perri, Daniela Di Paolo, Danilo Marimpietri, Chiara Brignole
Supplementary Figure 1 from Therapeutic Targeting of TLR9 Inhibits Cell Growth and Induces Apoptosis in Neuroblastoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9850314d1f14cbf9fd38a087f04fa511
https://doi.org/10.1158/0008-5472.22385993
https://doi.org/10.1158/0008-5472.22385993
Autor:
Gennaro De Libero, Monique Gannagé, Monica Loi, Jan D. Lünemann, Svenja Ewert, Christian W. Keller, Stefan Freigang, Christian Münz, Romina Theiler, Isaak Quast
Publikováno v:
Autophagy
Invariant natural killer T (iNKT) cells are innate T cells with powerful immune regulatory functions that recognize glycolipid antigens presented by the CD1D protein. While iNKT cell-activating glycolipids are currently being explored for their effic
Autor:
Laura Emionite, Monica Loi, Emanuela Ognio, Patrizia Perri, Vangelis Kondylis, Antonio Daga, Fabian Schorn, Irene Cossu, Chiara Brignole, Domenico Ribatti, Manolis Pasparakis, Daniele Murgia, Fabio Pastorino, Francesca Piaggio, Federica Raggi, Christian Marinaccio, Mirco Ponzoni, Daniela Di Paolo
Publikováno v:
Journal of Controlled Release. 223:165-177
The depletion of tumor-associated macrophages (TAMs), involved in different stages of cancer development and progression, is an appealing strategy in cancer therapy. We developed novel Clodronate-containing liposomes (Clo-Lipo-DOTAP) presenting physi
Autor:
Laure-Anne Ligeon, Monique Gannagé, Jan D. Lünemann, Christian W. Keller, Christian Münz, Monica Loi
The macroautophagy machinery supports membrane remodeling and fusion events that lead to the engulfment of cytoplasmic constituents in autophagosomes and their degradation in lysosomes. The capacity of this machinery to regulate membrane adaptors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57712c87811a1c2fc0d538ba325b22a5
https://doi.org/10.5167/uzh-165549
https://doi.org/10.5167/uzh-165549
Autor:
Patrizia Perri, Domenico Ribatti, Beatrice Nico, Guendalina Zuccari, Michele Cilli, Gabriella Pagnan, Vito Pistoia, Irene Caffa, Mirco Ponzoni, Daniela Di Paolo, Monica Loi, Fabio Pastorino, Danilo Marimpietri, Chiara Brignole
Publikováno v:
Journal of Controlled Release; Vol 170
Neuroblastoma is an embryonal tumor originating from the simpatico-adrenal lineage of the neural crest. It approximately accounts for about 15% of all pediatric oncology deaths. Despite advances in multimodal therapy, metastatic neuroblastoma tumors
Autor:
Arianna Giacomini, Patrizia Perri, Monica Loi, Mirco Ponzoni, Pamela Becherini, Laura Emionite, D. Di Paolo, E. Destefanis, Chiara Brignole, Irene Cossu, M. Cilli, Fabio Pastorino, Francesca Piaggio
Publikováno v:
Journal of Controlled Release. 192:157-166
Neuroblastoma (NB), the most common and deadly extracranial solid tumour of childhood, represents a challenging in paediatric oncology. Soluble tumour necrosis factor (TNF)-related apoptosis-inducing ligand (sTRAIL) is a cancer cell-specific molecule