Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Monica L. Husby"'
Autor:
Silvia Vaena, Paramita Chakraborty, Han Gyul Lee, Alhaji H. Janneh, Mohamed Faisal Kassir, Gyda Beeson, Zachariah Hedley, Ahmet Yalcinkaya, M. Hanief Sofi, Hong Li, Monica L. Husby, Robert V. Stahelin, Xue-Zhong Yu, Shikhar Mehrotra, Besim Ogretmen
Publikováno v:
Cell Reports, Vol 35, Iss 5, Pp 109076- (2021)
Summary: We lack a mechanistic understanding of aging-mediated changes in mitochondrial bioenergetics and lipid metabolism that affect T cell function. The bioactive sphingolipid ceramide, induced by aging stress, mediates mitophagy and cell death; h
Externí odkaz:
https://doaj.org/article/1e9021872d124ee9993e5c571f0785f7
Autor:
Kaveesha J. Wijesinghe, Luke McVeigh, Monica L. Husby, Nisha Bhattarai, Jia Ma, Bernard S. Gerstman, Prem P. Chapagain, Robert V. Stahelin
Publikováno v:
Viruses, Vol 12, Iss 4, p 482 (2020)
Marburg virus (MARV) is a lipid-enveloped negative sense single stranded RNA virus, which can cause a deadly hemorrhagic fever. MARV encodes seven proteins, including VP40 (mVP40), a matrix protein that interacts with the cytoplasmic leaflet of the h
Externí odkaz:
https://doaj.org/article/2cbf1afdc68c4152b39a754ce1321ef4
Autor:
Monica L Husby, Souad Amiar, Laura I Prugar, Emily A David, Caroline B Plescia, Kathleen E Huie, Jennifer M Brannan, John M Dye, Elsje Pienaar, Robert V Stahelin
Publikováno v:
EMBO reports. 23
Phosphatidylserine (PS) is a critical lipid factor in the assembly and spread of numerous lipid-enveloped viruses. Here, we describe the ability of the Ebola virus (EBOV) matrix protein eVP40 to induce clustering of PS and promote viral budding in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb529cf4843956aa9e693ee059c99dd
https://doi.org/10.15252/embr.202051709
https://doi.org/10.15252/embr.202051709
Plasma membrane (PM) domains and order phases have been shown to play a key role in the assembly, release, and entry of several lipid-enveloped viruses. In the present study, we provide a mechanistic understanding of the Ebola virus (EBOV) matrix pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08a86c0ca35510541e83ed0f99b997c9
https://doi.org/10.1101/2022.08.24.505195
https://doi.org/10.1101/2022.08.24.505195
Autor:
Michael J. Norris, Monica L. Husby, William B. Kiosses, Jieyun Yin, Roopashi Saxena, Linda J. Rennick, Anja Heiner, Stephanie S. Harkins, Rudramani Pokhrel, Sharon L. Schendel, Kathryn M. Hastie, Sara Landeras-Bueno, Zhe Li Salie, Benhur Lee, Prem P. Chapagain, Andrea Maisner, W. Paul Duprex, Robert V. Stahelin, Erica Ollmann Saphire
Publikováno v:
Science advances. 8(29)
Measles virus, Nipah virus, and multiple other paramyxoviruses cause disease outbreaks in humans and animals worldwide. The paramyxovirus matrix (M) protein mediates virion assembly and budding from host cell membranes. M is thus a key target for ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23791dc78f2e102b82b512026807abfe
https://pubmed.ncbi.nlm.nih.gov/35857835
https://pubmed.ncbi.nlm.nih.gov/35857835
Autor:
Xiao Liu, Ethan J. Pappas, Monica L. Husby, Balindile B. Motsa, Robert V. Stahelin, Elsje Pienaar
Publikováno v:
The Journal of biological chemistry. 298(7)
Ebola virus (EBOV) infections continue to pose a global public health threat, with high mortality rates and sporadic outbreaks in Central and Western Africa. A quantitative understanding of the key processes driving EBOV assembly and budding could pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11aecda0c7e5dccc067f8f4bae05d6a6
https://pubmed.ncbi.nlm.nih.gov/35568195
https://pubmed.ncbi.nlm.nih.gov/35568195
Autor:
Sharon L. Schendel, Kathryn M. Hastie, Robert V. Stahelin, Linda J. Rennick, A. Heiner, Rudramani Pokhrel, A. Maisner, Sara Landeras-Bueno, W. P. Duprex, S. S. Harkins, M. J. Norris, J. Yin, Prem P. Chapagain, Monica L. Husby, Z. Li Salie, William B. Kiosses, E. Ollmann Saphire, Brendan Lee
Measles virus, Nipah virus, and multiple other paramyxoviruses cause disease outbreaks in humans and animals worldwide. The paramyxovirus matrix (M) protein mediates virion assembly and budding from host cell membranes. M is thus a key target for ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7d9b5721ebc87e7cc52988a147e9f80
https://doi.org/10.1101/2021.10.11.463969
https://doi.org/10.1101/2021.10.11.463969
Autor:
Robert V. Stahelin, Monica L. Husby, Emily A. David, Plescia Cb, Laura I. Prugar, Souad Amiar, John M. Dye, Kathleen E. Huie, Elsje Pienaar, Jennifer M. Brannan
Phosphatidylserine (PS) has been shown to be a critical lipid factor in the assembly and spread of numerous lipid enveloped viruses. Here, we describe the ability of the Ebola virus (EBOV) matrix protein eVP40 to induce clustering of PS and promote v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e54f7ba2a36f7436775de2828fea477
https://doi.org/10.1101/2021.06.08.447555
https://doi.org/10.1101/2021.06.08.447555
Autor:
Alhaji H Janneh, Hong Li, Zachariah Hedley, Xue-Zhong Yu, Mohamed Faisal Kassir, Shikhar Mehrotra, Robert V. Stahelin, Besim Ogretmen, M. Hanief Sofi, Gyda C. Beeson, Paramita Chakraborty, Ahmet Yalcinkaya, Monica L. Husby, Silvia G. Vaena, Han Gyul Lee
Publikováno v:
Cell Reports, Vol 35, Iss 5, Pp 109076-(2021)
Cell reports
Cell reports
SUMMARY We lack a mechanistic understanding of aging-mediated changes in mitochondrial bioenergetics and lipid metabolism that affect T cell function. The bioactive sphingolipid ceramide, induced by aging stress, mediates mitophagy and cell death; ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e766caf701f080dd29045e0fb651782
http://www.sciencedirect.com/science/article/pii/S2211124721004071
http://www.sciencedirect.com/science/article/pii/S2211124721004071
Autor:
Monica L. Husby, Kaveesha J. Wijesinghe, Robert V. Stahelin, Stephanie Angel, Souad Amiar, Nisha Bhattarai, Sheng Li, Prem P. Chapagain, Bernard S. Gerstman
Publikováno v:
The Journal of Biological Chemistry
Marburg virus (MARV) is a lipid-enveloped virus harboring a negative-sense RNA genome, which has caused sporadic outbreaks of viral hemorrhagic fever in sub-Saharan Africa. MARV assembles and buds from the host cell plasma membrane where MARV matrix
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c596ddf7083efd6e77a8422284dff29e
http://europepmc.org/articles/PMC8191294
http://europepmc.org/articles/PMC8191294