Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Monica L Vetter"'
Autor:
Sarah Rose Anderson, Jacqueline M Roberts, Nathaniel Ghena, Emmalyn A Irvin, Joon Schwakopf, Isabelle B Cooperstein, Alejandra Bosco, Monica L Vetter
Publikováno v:
eLife, Vol 11 (2022)
Microglia serve critical remodeling roles that shape the developing nervous system, responding to the changing neural environment with phagocytosis or soluble factor secretion. Recent single-cell sequencing (scRNAseq) studies have revealed the contex
Externí odkaz:
https://doaj.org/article/3a78b58eddf44f7187167a01a59d3f1d
Autor:
Kevin T Breen, Sarah R Anderson, Michael R Steele, David J Calkins, Alejandra Bosco, Monica L Vetter
Publikováno v:
Frontiers in Neuroscience, Vol 10 (2016)
Neurodegeneration in glaucoma results in decline and loss of retinal ganglion cells (RGCs), and is associated with activation of myeloid cells such as microglia and macrophages. The chemokine fractalkine (FKN or Cx3cl1) mediates communication from ne
Externí odkaz:
https://doaj.org/article/6be63ddc9aba4e128bfb3400c54d959b
Autor:
Alejandra Bosco, Samuel D Crish, Michael R Steele, Cesar O Romero, Denise M Inman, Philip J Horner, David J Calkins, Monica L Vetter
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43602 (2012)
Glaucoma is a neurodegenerative disease that results in the progressive decline and ultimate death of retinal ganglion cells (RGCs). While multiple risk factors are associated with glaucoma, the mechanisms leading to onset and progression of the dise
Externí odkaz:
https://doaj.org/article/3a10033f1acd459c89a9afb505aa51fa
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112416- (2023)
Externí odkaz:
https://doaj.org/article/3bc7439c46fa467d8b68595adba11151
Autor:
Sarah Rose Anderson, Jacqueline M Roberts, Nathaniel Ghena, Emmalyn A Irvin, Joon Schwakopf, Isabelle B Cooperstein, Alejandra Bosco, Monica L Vetter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2e301fa3088d62f7af4565fe1a5a2ff
https://doi.org/10.7554/elife.76564.sa2
https://doi.org/10.7554/elife.76564.sa2
Autor:
Cesar O. Romero, Michael R. Steele, Sarah R. Anderson, Amanda G. Kautzman, Monica L. Vetter, Jianmin Zhang, Dorothy P. Schafer
Publikováno v:
The Journal of Neuroscience. 39:2025-2040
Microglia play important roles in shaping the developing CNS, and at early stages they have been proposed to regulate progenitor proliferation, differentiation, and neuronal survival. However, these studies reveal contradictory outcomes, highlighting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67ac992fe02308e577a2c189bf61c72
https://doi.org/10.1523/jneurosci.1854-18.2018
https://doi.org/10.1523/jneurosci.1854-18.2018
Publikováno v:
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Retinal development follows a conserved neurogenic program in vertebrates to orchestrate the generation of specific cell types from multipotent progenitors in sequential but overlapping waves. In this program, retinal ganglion cells (RGCs) are the fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a285fb2f66c2c5446e18d44a2f14adc5
https://doi.org/10.3389/fcell.2020.581136
https://doi.org/10.3389/fcell.2020.581136
Glial coverage in the optic nerve expands in proportion to optic axon loss in chronic mouse glaucoma
Autor:
Sarah R. Anderson, Monica L. Vetter, Alejandra Bosco, Kevin T. Breen, Michael R. Steele, David J. Calkins
Publikováno v:
Experimental Eye Research. 150:34-43
Within the white matter, axonal loss by neurodegeneration is coupled to glial cell changes in gene expression, structure and function commonly termed gliosis. Recently, we described the highly variable expansion of gliosis alebosco@neuro.utah.edu in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8b24bd70f460a05f61ff9b08315f643
https://doi.org/10.1016/j.exer.2016.01.014
https://doi.org/10.1016/j.exer.2016.01.014
Autor:
Sarah R. Anderson, Monica L. Vetter
Publikováno v:
Developmental Dynamics.
Microglia are engineers of the central nervous system (CNS) both in health and disease. In addition to the canonical immunological roles of clearing damaging entities and limiting the spread of toxicity and death, microglia remodel the CNS throughout
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68bffb1da141a91ebb936bda0a38708c
https://doi.org/10.1002/dvdy.1
https://doi.org/10.1002/dvdy.1
Autor:
Alejandra Bosco, Michael R. Steele, Cesar O. Romero, William W. Hauswirth, Sanford L. Boye, Kevin T. Breen, Vince A. Chiodo, Sarah R. Anderson, Stephen Tomlinson, Monica L. Vetter
Dysregulation of the complement system is implicated in neurodegeneration, including human and animal glaucoma. Optic nerve and retinal damage in glaucoma is preceded by local complement upregulation and activation, but whether targeting this early i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc1ea28ca67073736646c85b51a0105c
https://doi.org/10.1101/369181
https://doi.org/10.1101/369181