Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Monica L Hu"'
Autor:
Jiang-Hui Wang, Grace E. Lidgerwood, Maciej Daniszewski, Monica L. Hu, Georgina E. Roberts, Raymond C. B. Wong, Sandy S. C. Hung, Michelle E. McClements, Alex W. Hewitt, Alice Pébay, Doron G. Hickey, Thomas L. Edwards
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Bietti crystalline dystrophy (BCD) is an inherited retinal disease (IRD) caused by mutations in the CYP4V2 gene. It is a relatively common cause of IRD in east Asia. A number of features of this disease make it highly amenable to gene supple
Externí odkaz:
https://doaj.org/article/92f20941b1a14782b8b22261c0464675
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2023)
Inherited retinal diseases (IRDs) are associated with mutations in over 250 genes and represent a major cause of irreversible blindness worldwide. While gene augmentation or gene editing therapies could address the underlying genetic mutations in a s
Externí odkaz:
https://doaj.org/article/f8e67075be7a47109f11bad36e7c6a77
Autor:
Grace A. Borchert, Hoda Shamsnajafabadi, Monica L. Hu, Samantha R. De Silva, Susan M. Downes, Robert E. MacLaren, Kanmin Xue, Jasmina Cehajic-Kapetanovic
Publikováno v:
Cells, Vol 12, Iss 16, p 2092 (2023)
Age-related macular degeneration (AMD) is the leading cause of vision loss and visual impairment in people over 50 years of age. In the current therapeutic landscape, intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapies have bee
Externí odkaz:
https://doaj.org/article/cfce0e3fe683470994b7e5a8b62f0ae4
Publikováno v:
Life, Vol 11, Iss 7, p 635 (2021)
Age-related macular degeneration (AMD) is a multifactorial retinal disorder that is a major global cause of severe visual impairment. The development of an effective therapy to treat geographic atrophy, the predominant form of AMD, remains elusive du
Externí odkaz:
https://doaj.org/article/47f251ac16454ac7a081970a1309e684
Autor:
Jiang-Hui Wang, Grace E. Lidgerwood, Maciej Daniszewski, Monica L. Hu, Georgina E. Roberts, Raymond C. B. Wong, Sandy S. C. Hung, Michelle E. McClements, Alex W. Hewitt, Alice Pébay, Doron G. Hickey, Thomas L. Edwards
Publikováno v:
Scientific reports. 12(1)
Bietti crystalline dystrophy (BCD) is an inherited retinal disease (IRD) caused by mutations in the CYP4V2 gene. It is a relatively common cause of IRD in east Asia. A number of features of this disease make it highly amenable to gene supplementation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871d3751b56959dd01c0ab7da7fff3f9
https://pubmed.ncbi.nlm.nih.gov/35680963
https://pubmed.ncbi.nlm.nih.gov/35680963
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience
Frontiers in Neuroscience
Vernier acuity measures the ability to detect a misalignment or positional offset between visual stimuli, for example between two vertical lines when reading a vernier scale. It is considered a form of visual hyperacuity due to its detectable thresho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c23ec1a9e9140baea7175b05d16f0765
https://www.frontiersin.org/articles/10.3389/fnins.2021.714843/full
https://www.frontiersin.org/articles/10.3389/fnins.2021.714843/full
Publikováno v:
Life, Vol 11, Iss 635, p 635 (2021)
Life
Life
Age-related macular degeneration (AMD) is a multifactorial retinal disorder that is a major global cause of severe visual impairment. The development of an effective therapy to treat geographic atrophy, the predominant form of AMD, remains elusive du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17167ef088f5abd94e0084a3566b312e
https://www.mdpi.com/2075-1729/11/7/635
https://www.mdpi.com/2075-1729/11/7/635
Autor:
Fleur O'Hare, Monica L Hu, Thomas L Edwards, Jiang-Hui Wang, Doron G. Hickey, Zhengyang Liu, Lauren N Ayton
Publikováno v:
Clinicalexperimental optometry. 104(4)
Inherited retinal diseases (IRDs) comprise a heterogeneous group of genetic disorders affecting the retina. Caused by mutations in over 300 genes, IRDs result in visual impairment due to dysfunction and degeneration of photoreceptors, retinal pigment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b288413b0ac01a323792827a4a473f
https://pubmed.ncbi.nlm.nih.gov/33689657
https://pubmed.ncbi.nlm.nih.gov/33689657
Autor:
Thomas L Edwards, Zhengyang Liu, Lauren N Ayton, Jiang-Hui Wang, Monica L Hu, Alexis Ceecee Zhang, Fleur O'Hare, Doron G. Hickey
Publikováno v:
Clinicalexperimental optometry. 104(4)
This review presents the phenotypic and genotypic profiles of a select group of inherited retinal diseases (IRDs) that are currently the focus of retinal gene therapy trials globally. Research progress in IRD treatment trials may soon lead to their a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ba2ab22b659aa054d61e5989854a72d
https://pubmed.ncbi.nlm.nih.gov/33689629
https://pubmed.ncbi.nlm.nih.gov/33689629
Autor:
Jahan C. Penny-Dimri, Janan Arslan, Alexis Ceecee Britten-Jones, Dev Raveendran, Luke A Perry, Lauren N Ayton, Thomas L Edwards, Zhengyang Liu, Fleur O'Hare, Monica L Hu
Publikováno v:
Acta ophthalmologicaReferences. 100(3)
The neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) are emerging haematological inflammatory biomarkers. However, their significance in retinal vein occlusion (RVO) and its subtypes, branch and central RVO (BRVO and CRVO, respec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5459d2fd6f01b92923df245f3ab2fc7a
https://pubmed.ncbi.nlm.nih.gov/34219390
https://pubmed.ncbi.nlm.nih.gov/34219390