Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Monica Keen"'
Autor:
Esther Bouman-Thio, Qingmin Wang, Bart Frederick, Yaowei Zhu, Honghui Zhou, Joseph C. Marini, Hugh M. Davis, Kevin J. Petty, Monica Keen
Publikováno v:
Clinical drug investigation. 33(4)
Ustekinumab, a human immunoglobulin G1 kappa (IgG1κ) monoclonal antibody against interleukin-12/23p40, has been reported to be significantly efficacious in treating patients with moderate-to-severe plaque psoriasis. Although the efficacy and safety
Autor:
Dick E. de Vries, Kevin J. Petty, Joyce Ford, Yanli Zhuang, Bart Frederick, Mittie K. Doyle, Hugh M. Davis, Honghui Zhou, Zhenhua Xu, Monica Keen
Publikováno v:
Clinical therapeutics. 34(1)
Background The pharmacokinetics of golimumab, a human monoclonal antibody that inhibits the activity of tumor necrosis factor α, after a single subcutaneous (SC) or intravenous (IV) administration have been previously studied. Objectives The purpose
Autor:
Qingmin Wang, Joseph C. Marini, Zhenhua Xu, David Snead, Yanli Zhuang, Bart Frederick, Hong Yan, Esther Bouman-Thio, Monica Keen, Honghui Zhou, Hugh M. Davis
Publikováno v:
Journal of clinical pharmacology. 50(3)
This study characterized the pharmacokinetics (PK) of golimumab, an antitumor necrosis factor alpha human IgG1kappa monoclonal antibody, after a single intravenous (IV) or subcutaneous (SC) administration in healthy subjects and determined the absolu