Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Monica Faronato"'
Autor:
Lalita Priyamvada, Wouter W Kallemeijn, Monica Faronato, Kimberly Wilkins, Cynthia S Goldsmith, Catherine A Cotter, Suany Ojeda, Roberto Solari, Bernard Moss, Edward W Tate, Panayampalli Subbian Satheshkumar
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010662 (2022)
We have recently shown that the replication of rhinovirus, poliovirus and foot-and-mouth disease virus requires the co-translational N-myristoylation of viral proteins by human host cell N-myristoyltransferases (NMTs), and is inhibited by treatment w
Externí odkaz:
https://doaj.org/article/1b85968db8404d64b270c818449b4213
Autor:
Ylenia Perone, Aaron J. Farrugia, Alba Rodríguez-Meira, Balázs Győrffy, Charlotte Ion, Andrea Uggetti, Antonios Chronopoulos, Pasquale Marrazzo, Monica Faronato, Sami Shousha, Claire Davies, Jennifer H. Steel, Naina Patel, Armando del Rio Hernandez, Charles Coombes, Giancarlo Pruneri, Adrian Lim, Fernando Calvo, Luca Magnani
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
ERα breast cancer can relapse to metastatic disease following endocrine therapy. Here, the authors find that when aromatase inhibitor treatment resistance develops, epigenomic reprogramming drives Keratin-80 upregulation via SREBP1, and promotes cyt
Externí odkaz:
https://doaj.org/article/89df65835066448cbf1f8b48e72f3298
Autor:
Van T. M. Nguyen, Iros Barozzi, Monica Faronato, Ylenia Lombardo, Jennifer H. Steel, Naina Patel, Philippa Darbre, Leandro Castellano, Balázs Győrffy, Laura Woodley, Alba Rodriguez-Meira, Darren K. Patten, Valentina Vircillo, Manikandan Periyasamy, Simak Ali, Gianmaria Frige, Saverio Minucci, R. Charles Coombes, Luca Magnani
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/69915c68314f4c4da72a9fec0920fcd9
Autor:
Ylenia Perone, Aaron J. Farrugia, Alba Rodríguez-Meira, Balázs Győrffy, Charlotte Ion, Andrea Uggetti, Antonios Chronopoulos, Pasquale Marrazzo, Monica Faronato, Sami Shousha, Claire Davies, Jennifer H. Steel, Naina Patel, Armando del Rio Hernandez, Charles Coombes, Giancarlo Pruneri, Adrian Lim, Fernando Calvo, Luca Magnani
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/fff95096dfe94029b18485fd44cda673
Autor:
James Zhang, Gregor A. Lueg, Monica Faronato, Evon Poon, Andrii Gorelik, Andrea G. Grocin, Eva Caamano-Gutierrez, Francesco Falciani, Roberto Solari, Robin Carr, Andrew S. Bell, Edward Bartlett, Jennie Hutton, Miriam Llorian-Sopena, Probir Chakravarty, Bernadette Brzezicha, Martin Janz, Matther J. Garnett, Louis Chesler, Dinis P. Calado, Edward W. Tate
Publikováno v:
Cancer Research. 83:4871-4871
N-myristoyltransferases (NMTs) catalyze the protein N-terminal modification N-myristoylation, a lipidation event which affects >150 proteins and is involved in protein localization, stability, and function. NMT has been suggested as a target in cance
Autor:
Gregor A. Lueg, Bartlett E, Martin Janz, Probir Chakravarty, Dinis Pedro Calado, Miriam Llorian-Sopena, Mathew J. Garnett, Carr R, Monica Faronato, Andrew Simon Bell, Roberto Solari, Andrii Gorelik, Edward W. Tate, J.A. Hutton, Francesco Falciani, Eva Caamaño-Gutiérrez, Brzezicha B, Goya Grocin A
Human N-myristoyltransferases (NMTs) catalyze N-terminal protein myristoylation, a modification regulating membrane trafficking and interactions of >100 proteins. NMT is a promising target in cancer, but a mechanistic rationale for targeted therapy r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8cb3010b24b75d18b70086cbba79e19
https://doi.org/10.1101/2021.03.20.436222
https://doi.org/10.1101/2021.03.20.436222
Autor:
Charlotte Ion, Alba Rodriguez-Meira, Armando del Río Hernández, Naina Patel, Pasquale Marrazzo, Adrian Lim, Aaron J. Farrugia, Jennifer H. Steel, Antonios Chronopoulos, Monica Faronato, Charles Coombes, Luca Magnani, Balázs Győrffy, Claire Davies, Andrea Uggetti, Sami Shousha, Giancarlo Pruneri, Fernando Calvo, Ylenia Perone
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
Approximately 30% of ERα breast cancer patients relapse with metastatic disease following adjuvant endocrine therapies. The connection between acquisition of drug resistance and invasive potential is poorly understood. In this study, we demonstrate
Autor:
Wouter W, Kallemeijn, Gregor A, Lueg, Monica, Faronato, Kate, Hadavizadeh, Andrea, Goya Grocin, Ok-Ryul, Song, Michael, Howell, Dinis P, Calado, Edward W, Tate
Publikováno v:
Cell Chemical Biology
Summary On-target, cell-active chemical probes are of fundamental importance in chemical and cell biology, whereas poorly characterized probes often lead to invalid conclusions. Human N-myristoyltransferase (NMT) has attracted increasing interest as
Autor:
Andrii Gorelik, Dinis Pedro Calado, Gregor A. Lueg, Mathew J. Garnett, Monica Faronato, Bernadette Brzezicha, Miriam Llorian-Sopena, Andrea G. Grocin, Probir Chakravarty, Edward W. Tate, Martin Janz
Publikováno v:
Blood Cancer Discovery. 1:IA30-IA30
Human N-myristoyltransferase (NMT) 1 and 2 catalyze N-terminal protein myristoylation, a modification that regulates membrane trafficking and interactions of >100 proteins. NMT has been proposed as a target in cancer, but a rationale for selectivity
Autor:
Ylenia Perone, Balazs Gyorffy, Jenny Steel, Alba Rodriguez Meira, Andrea Uggetti, Antonios Chronopoulos, Armando del Río Hernández, Fernando Calvo, Darren K. Patten, R. C. Coombes, Adrian Lim, Luca Magnani, Sami Shousha, Aaron J. Farrugia, Charlotte Ion, Giancarlo Pruneri, Naina Patel, Monica Faronato, Claire Davies
Approximately 30% of women diagnosed with ERα breast cancer relapse with metastatic disease following adjuvant treatment with endocrine therapies1,2. The connection between acquisition of drug resistance and invasive potential is poorly understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c01c8eda64df43d8aa7bce9670e9e9a