Výsledky vyhledávání - "Monica Escarceller"

Fanconi anemia C gene product plays a role in the fidelity of blunt DNA end-joining

Autor: Stephen P. Jackson, P. A. Jeggo, B. K. Singleton, Ethel Moustacchi, Dora Papadopoulo, M Buchwald, Monica Escarceller

Publikováno v: Journal of Molecular Biology. 279:375-385

Mutations in genes controlling the correct functioning of the replicative, repair and recombination machineries may lead to genomic instability. A high level of spontaneous chromosomal aberrations amplified by treatment with DNA cross-linking agents

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::461576f8be62f98a1c55e592ce07e9d1
https://doi.org/10.1006/jmbi.1998.1784

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Arrest of S-phase progression is impaired in Fanconi anemia cells

Autor: Ethel Moustacchi, Danielle Rouillard, Agnès Laquerbe, Monica Escarceller, Maria Sala-Trepat, Dora Papadopoulo

Publikováno v: Experimental cell research. 260(2)

Fanconi anemia (FA) is an inherited cancer-susceptibility disorder, characterized by genomic instability, hypersensitivity to DNA cross-linking agents, and a prolonged G2 phase of the cell cycle. We observed a marked dose-dependent accumulation of FA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650d03b601277aae2ecb458f7ab1455a
https://pubmed.ncbi.nlm.nih.gov/11035915

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The fidelity of double strand breaks processing is impaired in complementation groups B and D of Fanconi anemia, a genetic instability syndrome

Autor: Monica Escarceller, Ethel Moustacchi, Dora Papadopoulo, Solange Rousset

Publikováno v: Somatic cell and molecular genetics. 23(6)

In mammalian cells, nonhomologous end-joining is the predominant mechanism to eliminate DNA double strand breaks. Such events are at the origin of deletion mutagenesis and chromosomal rearrangements. The hallmark of Fanconi anemia, an inherited cance

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2f06d689d00c65026db178b247a0ab
https://pubmed.ncbi.nlm.nih.gov/9661703

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P IX.24 The fidelity of DNA double strand break (DSB) processing is impaired in Fanconi anemia cells

Autor: Ethel Moustacchi, Monica Escarceller, Dora Papadopoulo, Solange Rousset

Publikováno v: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 379:S67

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::98a9fad2eb266db53437fa153bdacd6b
https://doi.org/10.1016/s0027-5107(97)82829-1

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