Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Monica E. Brown"'
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 843-856 (2022)
The epithelial lining of the intestine, particularly the stem cell compartment, is affected by harsh conditions in the luminal environment and also is susceptible to genotoxic agents such as radiation and chemotherapy. Therefore, the ability for inte
Externí odkaz:
https://doaj.org/article/27947606b650451fbea21618499f5855
Autor:
Hayley J Hawkins, Betelehem W Yacob, Monica E Brown, Brandon R Goldstein, John J Arcaroli, Stacey M Bagby, Sarah J Hartman, Morgan Macbeth, Andrew Goodspeed, Thomas Danhorn, Robert W Lentz, Christopher H Lieu, Alexis D Leal, Wells A Messersmith, Peter J Dempsey, Todd M Pitts
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0298808 (2024)
Pancreatic ductal adenocarcinoma (PDAC) presents at advanced stages and is refractory to most treatment modalities. Wnt signaling activation plays a critical role in proliferation and chemotherapeutic resistance. Minimal media conditions, growth fact
Externí odkaz:
https://doaj.org/article/acf54b5fa52843b4b67f450c4a49baa5
Autor:
Nikolce Gjorevski, Tobin E. Brown, Matthias P. Lutolf, Monica E. Brown, Peter J. Dempsey, F. Max Yavitt, Ella A. Hushka, Kristi S. Anseth
Publikováno v:
Adv Mater
Intestinal organoids have proven to be useful in vitro models for many basic and translational studies aimed at understanding and treating disease. However, their routine culture relies on animal derived matrices that limit their utility for clinical