Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Monica Di Padova"'
Autor:
Mauro Di Vito Nolfi, Davide Vecchiotti, Irene Flati, Daniela Verzella, Monica Di Padova, Edoardo Alesse, Daria Capece, Francesca Zazzeroni
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Drug resistance is a major impediment to patient survival and remains the primary cause of unsuccessful cancer therapy. Drug resistance occurs in many tumors and is frequently induced by chemotherapy which triggers a defensive response both in cancer
Externí odkaz:
https://doaj.org/article/f6dda65f89674c8583bac7082122c1da
Autor:
Barbara Di Francesco, Daniela Verzella, Gaetano Barbato, Monica Di Padova, Edoardo Alesse, Davide Vecchiotti, Daria Capece, Alessandra Tessitore, Irene Flati, Francesca Zazzeroni, Mauro Di Vito Nolfi, Chiara Compagnoni, Jessica Cornice
Publikováno v:
Genes
Volume 12
Issue 11
Genes, Vol 12, Iss 1726, p 1726 (2021)
Volume 12
Issue 11
Genes, Vol 12, Iss 1726, p 1726 (2021)
The detection of circulating microRNA (miRNA)-based biomarkers represents an innovative, non-invasive method for the early detection of cancer. However, the low concentration of miRNAs released in body fluids and the difficult identification of the t
Autor:
Barbara Di Francesco, Daniela Verzella, Daria Capece, Davide Vecchiotti, Mauro Di Vito Nolfi, Irene Flati, Jessica Cornice, Monica Di Padova, Adriano Angelucci, Edoardo Alesse, Francesca Zazzeroni
Publikováno v:
Cancers. 14:3557
Acute Myeloid Leukemia (AML) is an aggressive hematological malignancy that relies on highly heterogeneous cytogenetic alterations. Although in the last few years new agents have been developed for AML treatment, the overall survival prospects for AM
Autor:
Edoardo Alesse, Chiara Compagnoni, Veronica Zelli, Roberta Capelli, Jessica Cornice, Alessandra Tessitore, Davide Vecchiotti, Monica Di Padova, Francesca Zazzeroni, Alessandra Corrente
Publikováno v:
Genes, Vol 12, Iss 1447, p 1447 (2021)
Genes
Genes
The advent of Next Generation Sequencing technologies brought with it the discovery of several microRNA (miRNA) variants of heterogeneous lengths and/or sequences. Initially ascribed to sequencing errors/artifacts, these isoforms, named isomiRs, are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00f7a188b5aaaf4aac9fff54dd2bfc68
http://hdl.handle.net/11697/172814
http://hdl.handle.net/11697/172814
Autor:
Alessio Cortellini, Monica Di Padova, Adriano Angelucci, Corrado Ficorella, Simona Delle Monache
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 19, Iss 1, p 299 (2018)
International Journal of Molecular Sciences, Vol 19, Iss 1, p 299 (2018)
High expectations are placed upon anti-angiogenic compounds for metastatic colorectal cancer (mCRC), the first malignancy for which such type of treatment has been approved. Indeed, clinical trials have confirmed that targeting the formation of new v
Autor:
Silvia Soddu, Alessandro Porrello, Laura Zannini, Daniele Lecis, Tiziana Bruno, Domenico Delia, Aristide Floridi, Kum Kum Khanna, Simona Iezzi, Christian Jekimovs, Claudio Passananti, Marco Crescenzi, Carmen D'Angelo, Marco Scarsella, Francesca De Nicola, Maurizio Fanciulli, Alberto Chersi, Leopoldo Dimiziani, Monica Di Padova, Carlo Leonetti, Nicoletta Corbi
Publikováno v:
Cancer Cell. 10:473-486
SummaryChe-1 is a RNA polymerase II-binding protein involved in the transcription of E2F target genes and induction of cell proliferation. Here we show that Che-1 contributes to DNA damage response and that its depletion sensitizes cells to anticance
Publikováno v:
Genes & Development. 18:2627-2638
The Ezh2 protein endows the Polycomb PRC2 and PRC3 complexes with histone lysine methyltransferase (HKMT) activity that is associated with transcriptional repression. We report that Ezh2 expression was developmentally regulated in the myotome compart
Autor:
Maurizio Fanciulli, Monica Di Padova, Aristide Floridi, Nicoletta Corbi, Claudio Passananti, Simona Iezzi, Daniela Nicosia, Rita Gallo, Francesca De Nicola, Carmen D'Angelo, Annamaria Biroccio, Tiziana Bruno
Publikováno v:
Journal of Biological Chemistry. 278:36496-36504
Che-1 is a recently identified human RNA polymerase II binding protein involved in the regulation of gene transcription and cell proliferation. We previously demonstrated that Che-1 inhibits the Rb growth-suppressing function by interfering with Rb-m
Publikováno v:
Biochemical Pharmacology. 58:1009-1016
Ropivacaine is a new long-acting aminoamide local anesthetic with a reduced systemic and cardiac toxicity. Since the latter seems to be related, at least partially, to an interference with mitochondrial energy transduction, the effect of ropivacaine
Autor:
Monica Di Padova, Aristide Floridi, Tiziana Bruno, Maurizio Fanciulli, Claudio Passananti, Sarah Lovari, Roberta De Angelis
Publikováno v:
FEBS Letters. 427:236-240
We previously isolated the human RPB11 cDNA, encoding the 13.3 kDa subunit of RNA polymerase II, and demonstrated that expression of this subunit is modulated by doxorubicin. Using hRPB11 as bait in a yeast two-hybrid system, two cDNA variants encodi