Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Monica Civera"'
Autor:
Giulia Antonini, Monica Civera, Kanhaya Lal, Sarah Mazzotta, Annabelle Varrot, Anna Bernardi, Laura Belvisi
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Opportunistic infections from multidrug-resistant pathogens such as Burkholderia cenocepacia are a threatening risk for hospital-bound patients suffering from immunocompromised conditions or cystic fibrosis. B. cenocepacia BC2L-C lectin has been link
Externí odkaz:
https://doaj.org/article/917164ba495b4ced8dff663f7292d552
Autor:
Francesca Vasile, Francesca Lavore, Silvia Gazzola, Chiara Vettraino, Emilio Parisini, Umberto Piarulli, Laura Belvisi, Monica Civera
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Cadherins promote cell-cell adhesion by forming homophilic interactions via their N-terminal extracellular domains. Hence, they have broad-ranging physiological effects on tissue organization and homeostasis. When dysregulated, cadherins contribute t
Externí odkaz:
https://doaj.org/article/af8a3a8d9de941babe196495dd4cc944
New Chemotypes for the Inhibition of (p)ppGpp Synthesis in the Quest for New Antimicrobial Compounds
Autor:
Crescenzo Coppa, Luca Sorrentino, Monica Civera, Marco Minneci, Francesca Vasile, Sara Sattin
Publikováno v:
Molecules, Vol 27, Iss 10, p 3097 (2022)
Antimicrobial resistance (AMR) poses a serious threat to our society from both the medical and economic point of view, while the antibiotic discovery pipeline has been dwindling over the last decades. Targeting non-essential bacterial pathways, such
Externí odkaz:
https://doaj.org/article/1f1274a59fe44197b3929f2e7386b8a6
Autor:
Monica Civera, Sara Sattin
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Bacteria have developed different bet hedging strategies to survive hostile environments and stressful conditions with persistency being maybe the most elegant yet still poorly understood one. Persisters’ temporary tolerance to antibiotic treatment
Externí odkaz:
https://doaj.org/article/665d90d587ae4aa5863d3a7ee26b0124
Autor:
Cristina Di Carluccio, Rosa Ester Forgione, Marco Montefiori, Monica Civera, Sara Sattin, Giovanni Smaldone, K. Fukase, Y. Manabe, Paul R. Crocker, Antonio Molinaro, Roberta Marchetti, Alba Silipo
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101998- (2021)
Summary: Siglecs (sialic acid binding immunoglobulin (Ig)-like lectins) constitute a group of 15 human and 9 murine cell-surface transmembrane receptors belonging to the I-type lectin family, mostly expressed on innate immune cells and characterized
Externí odkaz:
https://doaj.org/article/a235801d51084937ad1d3362512574e7
Autor:
Monica Civera, Francesca Vasile, Donatella Potenza, Cinzia Colombo, Sara Parente, Chiara Vettraino, Tommaso Prosdocimi, Emilio Parisini, Laura Belvisi
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 6, p e1007041 (2019)
Cadherins are homophilic cell-cell adhesion molecules whose aberrant expression has often been shown to correlate with different stages of tumor progression. In this work, we investigate the interaction of two peptidomimetic ligands with the extracel
Externí odkaz:
https://doaj.org/article/d33a22f651e74a15b62bc32a70bb1629
Autor:
Silvia Panzeri, Daniela Arosio, Silvia Gazzola, Laura Belvisi, Monica Civera, Donatella Potenza, Francesca Vasile, Isabell Kemker, Thomas Ertl, Norbert Sewald, Oliver Reiser, Umberto Piarulli
Publikováno v:
Molecules, Vol 25, Iss 24, p 5966 (2020)
Integrin ligands containing the tripeptide sequences Arg-Gly-Asp (RGD) and iso-Asp-Gly- Arg (isoDGR) were actively investigated as inhibitors of tumor angiogenesis and directing unit in tumor-targeting drug conjugates. Reported herein is the synthesi
Externí odkaz:
https://doaj.org/article/81d3836bab5b4d81a04af9dfb7615e4e
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 1, p e1005334 (2017)
Understanding how binding events modulate functional motions of multidomain proteins is a major issue in chemical biology. We address several aspects of this problem by analyzing the differential dynamics of αvβ3 integrin bound to wild type (wtFN10
Externí odkaz:
https://doaj.org/article/165e3b0fe5004ee68443f68cc1fb658e
Publikováno v:
European journal of organic chemistry (Online) 2021 (2021): 4245–4259. doi:10.1002/ejoc.202100506
info:cnr-pdr/source/autori:Civera M.; Moroni E.; Sorrentino L.; Vasile F.; Sattin S./titolo:Chemical and Biophysical Approaches to Allosteric Modulation/doi:10.1002%2Fejoc.202100506/rivista:European journal of organic chemistry (Online)/anno:2021/pagina_da:4245/pagina_a:4259/intervallo_pagine:4245–4259/volume:2021
info:cnr-pdr/source/autori:Civera M.; Moroni E.; Sorrentino L.; Vasile F.; Sattin S./titolo:Chemical and Biophysical Approaches to Allosteric Modulation/doi:10.1002%2Fejoc.202100506/rivista:European journal of organic chemistry (Online)/anno:2021/pagina_da:4245/pagina_a:4259/intervallo_pagine:4245–4259/volume:2021
Allosteric regulation, i. e. the control exerted on an orthosteric site by an effector interacting at a distinct and distant site, represents a prime example of a precise tuning system of several key biological processes like gene transcription, cell
New Chemotypes for the Inhibition of (p)ppGpp Synthesis in the Quest for New Antimicrobial Compounds
Autor:
Sattin, Crescenzo Coppa, Luca Sorrentino, Monica Civera, Marco Minneci, Francesca Vasile, Sara
Publikováno v:
Molecules; Volume 27; Issue 10; Pages: 3097
Antimicrobial resistance (AMR) poses a serious threat to our society from both the medical and economic point of view, while the antibiotic discovery pipeline has been dwindling over the last decades. Targeting non-essential bacterial pathways, such