Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Monica Carmosino"'
Autor:
Serena Milano, Ilenia Saponara, Andrea Gerbino, Dominga Lapi, Ludovica Lela, Monica Carmosino, Massimo Dal Monte, Paola Bagnoli, Maria Svelto, Giuseppe Procino
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Efferent sympathetic nerve fibers regulate several renal functions activating norepinephrine receptors on tubular epithelial cells. Of the beta-adrenoceptors (β-ARs), we previously demonstrated the renal expression of β3-AR in the thick ascending l
Externí odkaz:
https://doaj.org/article/3fc5c08bb2d14180861e13fee54e3d87
Autor:
Giusy Pietrafesa, Roberta De Zio, Simona Ida Scorza, Maria Francesca Armentano, Martino Pepe, Cinzia Forleo, Giuseppe Procino, Andrea Gerbino, Maria Svelto, Monica Carmosino
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background We previously demonstrated that an Italian family affected by a severe dilated cardiomyopathy (DCM) with history of sudden deaths at young age, carried a mutation in the Lmna gene encoding for a truncated variant of the Lamin A/C
Externí odkaz:
https://doaj.org/article/558a2140ce16485286f3f41a5d580040
Autor:
Roberta De Zio, Giusy Pietrafesa, Serena Milano, Giuseppe Procino, Manuela Bramerio, Martino Pepe, Cinzia Forleo, Stefano Favale, Maria Svelto, Andrea Gerbino, Monica Carmosino
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
In this work, we studied an lmna nonsense mutation encoding for the C-terminally truncated Lamin A/C (LMNA) variant Q517X, which was described in patients affected by a severe arrhythmogenic cardiomyopathy with history of sudden death. We found that
Externí odkaz:
https://doaj.org/article/18505d3c954043df83a6195552a88a59
Autor:
Giorgia Schena, Monica Carmosino, Samantha Chiurlia, Laura Onuchic, Mauro Mastropasqua, Eugenio Maiorano, Francesco P. Schena, Michael J. Caplan
Publikováno v:
Physiological Reports, Vol 9, Iss 20, Pp n/a-n/a (2021)
Abstract Autosomal dominant polycystic kidney disease (ADPKD) disrupts renal parenchyma through progressive expansion of fluid‐filled cysts. The only approved pharmacotherapy for ADKPD involves the blockade of the vasopressin type 2 receptor (V2R).
Externí odkaz:
https://doaj.org/article/074bf8c607b8486189284e5954cd8661
Autor:
Serena Milano, Monica Carmosino, Andrea Gerbino, Ilenia Saponara, Dominga Lapi, Massimo Dal Monte, Paola Bagnoli, Maria Svelto, Giuseppe Procino
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
We previously showed that the beta-3 adrenergic receptor (BAR3) is expressed in most segments of the nephron where its agonism promotes a potent antidiuretic effect. We localized BAR3 in distal convoluted tubule (DCT) cells expressing the thiazide-se
Externí odkaz:
https://doaj.org/article/83ef7d0f0dce48859ef94af7a3df4cba
Autor:
Serena Milano, Andrea Gerbino, Giorgia Schena, Monica Carmosino, Maria Svelto, Giuseppe Procino
Publikováno v:
Cellular Physiology and Biochemistry, Vol 48, Iss 2, Pp 847-862 (2018)
Background/Aims: We recently showed that the β3-adrenoreceptor (β3AR) is expressed in mouse kidney collecting ducts (CD) cells along with the type-2 vasopressin receptor (AVPR2). Interestingly, a single injection of a β3AR selective agonist promot
Externí odkaz:
https://doaj.org/article/1f562968f9644c7a91ea0517bb649894
Autor:
Andrea Gerbino, Irene Bottillo, Serena Milano, Martina Lipari, Roberta De Zio, Silvia Morlino, Maria Grazia Mola, Giuseppe Procino, Federica Re, Elisabetta Zachara, Paola Grammatico, Maria Svelto, Monica Carmosino
Publikováno v:
Cellular Physiology and Biochemistry, Vol 44, Iss 4, Pp 1559-1577 (2017)
Background/Aims: Truncating LMNA gene mutations occur in many inherited cardiomyopathy cases, but the molecular mechanisms involved in the disease they cause have not yet been systematically investigated. Here, we studied a novel frameshift LMNA vari
Externí odkaz:
https://doaj.org/article/0303a5d654164150b0089dedd1ad0c82
Autor:
Rocchina Miglionico, Angela Ostuni, Maria Francesca Armentano, Luigi Milella, Elvira Crescenzi, Monica Carmosino, Faustino Bisaccia
Publikováno v:
Cellular & Molecular Biology Letters, Vol 22, Iss 1, Pp 1-10 (2017)
Abstract Background Pseudoxanthoma elasticum (PXE) is characterized by progressive ectopic mineralization of elastic fibers in dermal, ocular and vascular tissues. No effective treatment exists. It is caused by inactivating mutations in the gene enco
Externí odkaz:
https://doaj.org/article/f83b65e2d1d34765b83c0f539583827e
Autor:
Angela Ostuni, Monica Carmosino, Rocchina Miglionico, Vittorio Abruzzese, Fabio Martinelli, Daniela Russo, Ilaria Laurenzana, Agata Petillo, Faustino Bisaccia
Publikováno v:
Cells, Vol 9, Iss 6, p 1410 (2020)
ABCC6, belonging to sub-family C of ATP-binding cassette transporter, is an ATP-dependent transporter mainly present in the basolateral plasma membrane of hepatic and kidney cells. Although the substrates transported are still uncertain, ABCC6 has be
Externí odkaz:
https://doaj.org/article/b3edb826e20f486ab1d903f04435bc8a
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Nuclear lamin A/C are crucial components of the intricate protein mesh that underlies the inner nuclear membrane and confers mainly nuclear and cytosolic rigidity. However, throughout the years a number of other key physiological processes have been
Externí odkaz:
https://doaj.org/article/cd2c8eae2dcc46fd973fc17658e8973f