supplementary methods from Targeting the Wnt Pathway and Cancer Stem Cells with Anti-progastrin Humanized Antibodies as a Potential Treatment for K-RAS-Mutated Colorectal Cancer

Autor: Dominique Joubert, Marc Ychou, Alain Sézeur, Pascal Pujol, Jean-François Bourgaux, Frédéric Bibeau, Eric Assenat, Chris Planque, Véronique Saywell, Sophie Poupeau, Caroline Pfeiffer, Jérémy Ollier, Pierre Liaud, Amandine Durochat, Benjamin Dubuc, Bérengère Vire, Nathalie Cahuzac, Maud Flacelière, Jean-Marc Pascussi, Eric Morency, Thibault Mazard, Marie-Paule Lefranc, Guillaume Habif, Monica Cappellini, Alexandre Prieur

Contain all the supplementary methods linked to this paper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e16d1c1942cf3ef0e08c51a9a9e4d21
https://doi.org/10.1158/1078-0432.22467759

A novel method to detect hPG80 (human circulating progastrin) in the blood

Autor: Berengere Vire, Julien Soulé, Veronique Saywell, Lucile Canterel-Thouennon, Sylvia Tigrett, Erika Ortiz, Mélina Blairvacq, Emilie Blanc, Dominique Joubert, Alexandre Prieur, Maud Flacelière, Sophie Poupeau, Fanny Belouin, Pierre Liaud, Monica Cappellini

Publikováno v: Analytical Methods. 13:4468-4477

hPG80 (human circulating progastrin) is produced and released by cancer cells. We recently reported that hPG80 is detected in the blood of patients with cancers from different origins, suggesting its potential utility for cancer detection. To accurat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1edc1e9d0fef2f0710c13012fd8cfc81
https://doi.org/10.1039/d1ay00986a

Targeting the Wnt Pathway and Cancer Stem Cells with Anti-progastrin Humanized Antibodies as a Potential Treatment for K-RAS-Mutated Colorectal Cancer

Autor: Guillaume Habif, Eric Assenat, Alain Sézeur, Sophie Poupeau, Berengere Vire, Maud Flacelière, Amandine Durochat, Thibault Mazard, Jérémy Ollier, Frédéric Bibeau, Pascal Pujol, Veronique Saywell, Alexandre Prieur, Benjamin Dubuc, Jean-Marc Pascussi, Dominique Joubert, Chris Planque, Pierre Liaud, Marc Ychou, Eric Morency, Nathalie Cahuzac, Marie-Paule Lefranc, Monica Cappellini, Jean-François Bourgaux, Caroline Pfeiffer

Publikováno v: Clinical Cancer Research
Clinical Cancer Research, American Association for Cancer Research, 2017, 23 (17), pp.5267--5280. ⟨10.1158/1078-0432.CCR-17-0533⟩

Purpose: Patients with metastatic colorectal cancer suffer from disease relapse mainly due to cancer stem cells (CSC). Interestingly, they have an increased level of blood progastrin, a tumor-promoting peptide essential for the self-renewal of colon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76681188704f8d11e657b4d4a7e8d607
https://pubmed.ncbi.nlm.nih.gov/28600477