Výsledky vyhledávání - "Monica Brenca"

Akademický článek

Tumor genotype, location, and malignant potential shape the immunogenicity of primary untreated gastrointestinal stromal tumors

Autor: Daniela Gasparotto, Marta Sbaraglia, Sabrina Rossi, Davide Baldazzi, Monica Brenca, Alessia Mondello, Federica Nardi, Dominga Racanelli, Matilde Cacciatore, Angelo Paolo Dei Tos, Roberta Maestro

Publikováno v: JCI Insight, Vol 5, Iss 22 (2020)

Intratumoral immune infiltrate was recently reported in gastrointestinal stromal tumors (GISTs). However, the tumor-intrinsic factors that dictate GIST immunogenicity are still largely undefined. To shed light on this issue, a large cohort (82 sample

Externí odkaz: https://doaj.org/article/7b5685449a644f5298b7ad393fad87f9

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Akademický článek

The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness.

Autor: Eros Di Giorgio, Elisa Franforte, Sebastiano Cefalù, Sabrina Rossi, Angelo Paolo Dei Tos, Monica Brenca, Maurizio Polano, Roberta Maestro, Harikrishnareddy Paluvai, Raffaella Picco, Claudio Brancolini

Publikováno v: PLoS Genetics, Vol 13, Iss 4, p e1006752 (2017)

The contribution of MEF2 TFs to the tumorigenic process is still mysterious. Here we clarify that MEF2 can support both pro-oncogenic or tumor suppressive activities depending on the interaction with co-activators or co-repressors partners. Through t

Externí odkaz: https://doaj.org/article/ce22d3566e6d46abb5ecbdbb647d5627

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