Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Monica Beneyto"'
Autor:
Michael Piper, David A. Lewis, John J. McGrath, Darryl W. Eyles, Monica Beneyto, Thomas H. J. Burne
Publikováno v:
Psychiatric Clinics of North America. 35:571-584
The neurodevelopmental hypothesis of schizophrenia suggests that the disruption of early brain development increases the risk of later developing schizophrenia. This hypothesis focuses attention on critical periods of early brain development. From an
Autor:
David A. Lewis, Tanya Keenan, Guillermo Gonzalez-Burgos, Monica Beneyto, Takanori Hashimoto, Dominique Arion, Diana C. Rotaru, Quyen Nguyen
Publikováno v:
Biological Psychiatry. 65:1015-1023
In schizophrenia, working memory dysfunction is associated with altered expression of gamma-aminobutyric acid (GABA)(A) receptor alpha1 and alpha2 subunits in the dorsolateral prefrontal cortex (DLPFC). In rodents, cortical alpha subunit expression s
Publikováno v:
Neuropsychopharmacology. 33:2175-2186
The hypothesis of N-methyl-D-aspartate (NMDA) receptor hypofunction in schizophrenia was initially based on observations that blockade of the NMDA subtype of glutamate receptor by noncompetitive antagonists, such as phencyclidine and ketamine, can le
Autor:
James H. Meador-Woodruff, Daya S. Gupta, Emily Kreger, Monica Beneyto, Kenneth L. Davis, Vahram Haroutunian, Robert E. McCullumsmith
Publikováno v:
Schizophrenia Research. 90:15-27
Several recent studies have found changes in the expression of genes functionally related to myelination and oligodendrocyte homeostasis in schizophrenia. These studies utilized microarrays and quantitative PCR (QPCR), methodologies which do not perm
Publikováno v:
Molecular Psychiatry. 11:737-747
Abnormal expression of the N-methyl-D-Aspartate (NMDA) receptor and its interacting molecules of the postsynaptic density (PSD) are thought to be involved in the pathophysiology of schizophrenia. Frontal regions of neocortex including dorsolateral pr
Publikováno v:
Current Psychosis & Therapeutics Reports. 4:27-34
Schizophrenia is a severe mental illness affecting millions of people worldwide, with a substantial impact on patients, family, and society. Recent studies have established support for a hypothesis of abnormal glutamatergic neurotransmission in speci
Publikováno v:
Synapse. 60:585-598
Ampakines, positive AMPA receptor modulators, can improve cognitive function in schizophrenia, and enhancement of AMPA receptor-mediated currents by them potentiates the activity of antipsychotics. In vitro studies have revealed that trafficking of A
Publikováno v:
Annals of the New York Academy of Sciences. 1003:352-355
Publikováno v:
The Journal of Comparative Neurology. 468:530-554
Glutamate is the primary excitatory neurotransmitter in the central nervous system, regulating numerous cellular signaling pathways and controlling the excitability of central synapses both pre- and postsynaptically. Localization, cell surface expres
Autor:
Jorge J. Prieto, Monica Beneyto
Publikováno v:
Brain Research Bulletin. 54:485-498
We studied the connections of eleven auditory cortical areas with the claustrum and the endopiriform nucleus in the cat, by means of cortical injections of either wheat germ agglutinin conjugated to horseradish peroxidase, or biotinylated dextran ami