Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Monica Ballarino"'
Publikováno v:
Bio-Protocol, Vol 13, Iss 20 (2023)
The interaction of RNA with specific RNA-binding proteins (RBP) leads to the establishment of complex regulatory networks through which gene expression is controlled. Careful consideration should be given to the exact environment where a given RNA/RB
Externí odkaz:
https://doaj.org/article/411b5729d1e542cbba6c32950413fa7b
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4706-4716 (2023)
In recent years, research on long non-coding RNAs (lncRNAs) has gained considerable attention due to the increasing number of newly identified transcripts. Several characteristics make their functional evaluation challenging, which called for the urg
Externí odkaz:
https://doaj.org/article/8620032705fd43bc99da826723a0f2a5
Autor:
Valeria Taliani, Giulia Buonaiuto, Fabio Desideri, Adriano Setti, Tiziana Santini, Silvia Galfrè, Leonardo Schirone, Davide Mariani, Giacomo Frati, Valentina Valenti, Sebastiano Sciarretta, Emerald Perlas, Carmine Nicoletti, Antonio Musarò, Monica Ballarino
Publikováno v:
eLife, Vol 12 (2023)
Long noncoding RNAs (lncRNAs) are emerging as critical regulators of heart physiology and disease, although the studies unveiling their modes of action are still limited to few examples. We recently identified pCharme, a chromatin-associated lncRNA w
Externí odkaz:
https://doaj.org/article/3a640cbf46f84fc6b023fb2546f9993f
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Detecting RNA/RNA interactions in the context of a given cellular system is crucial to gain insights into the molecular mechanisms that stand beneath each specific RNA molecule. When it comes to non-protein coding RNA (ncRNAs), and especially to long
Externí odkaz:
https://doaj.org/article/92f0f385507e431ebaef350fcd20b2b7
Publikováno v:
Bio-Protocol, Vol 11, Iss 21 (2021)
LncRNAs have been recently implicated in the epigenetic control of muscle differentiation and their functional characterization has traditionally relied upon in vitro models of myogenic differentiation. However, the use of experimental paradigms to s
Externí odkaz:
https://doaj.org/article/06167189d5c24499b845fe2f7f25df5f
Autor:
Andrea Cipriano, Martina Macino, Giulia Buonaiuto, Tiziana Santini, Beatrice Biferali, Giovanna Peruzzi, Alessio Colantoni, Chiara Mozzetta, Monica Ballarino
Publikováno v:
eLife, Vol 10 (2021)
Skeletal muscle possesses an outstanding capacity to regenerate upon injury due to the adult muscle stem cell (MuSC) activity. This ability requires the proper balance between MuSC expansion and differentiation, which is critical for muscle homeostas
Externí odkaz:
https://doaj.org/article/6a30f5b61b7a4a6eb1cf1521278b7a36
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2020)
In 1957, Francis Crick speculated that RNA, beyond its protein-coding capacity, could have its own function. Decade after decade, this theory was dramatically boosted by the discovery of new classes of non-coding RNAs (ncRNAs), including long ncRNAs
Externí odkaz:
https://doaj.org/article/faa66be0bf1646cabdd2e5ef3ff6dbe5
The Long Non-coding RNA lnc-31 Interacts with Rock1 mRNA and Mediates Its YB-1-Dependent Translation
Autor:
Dacia Dimartino, Alessio Colantoni, Monica Ballarino, Julie Martone, Davide Mariani, Johannes Danner, Astrid Bruckmann, Gunter Meister, Mariangela Morlando, Irene Bozzoni
Publikováno v:
Cell Reports, Vol 23, Iss 3, Pp 733-740 (2018)
Summary: Cytoplasmic long non-coding RNAs have been shown to act at many different levels to control post-transcriptional gene expression, although their role in translational control is poorly understood. Here, we show that lnc-31, a non-coding RNA
Externí odkaz:
https://doaj.org/article/ec1c0ffdd1764928abb6e827d776c442
Publikováno v:
Cells, Vol 10, Iss 10, p 2512 (2021)
The ability of the ribonucleic acid (RNA) to self-replicate, combined with a unique cocktail of chemical properties, suggested the existence of an RNA world at the origin of life. Nowadays, this hypothesis is supported by innovative high-throughput a
Externí odkaz:
https://doaj.org/article/784411dfba6540d0924cebce71b6c1a3
Autor:
Andrea Cipriano, Monica Ballarino
Publikováno v:
Frontiers in Molecular Biosciences, Vol 5 (2018)
The completion of the human genome sequence together with advances in sequencing technologies have shifted the paradigm of the genome, as composed of discrete and hereditable coding entities, and have shown the abundance of functional noncoding DNA.
Externí odkaz:
https://doaj.org/article/10534e470d754ab699c831146083d6a9