Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Monica Baiula"'
Publikováno v:
Biomedicines, Vol 12, Iss 2, p 316 (2024)
Integrins are heterodimeric cell-surface receptors that regulate cell–cell adhesion and cellular functions through bidirectional signaling. On the other hand, anomalous trafficking of integrins is also implicated in severe pathologies as cancer, th
Externí odkaz:
https://doaj.org/article/de44bb42e1ef477d98086360e5f0f973
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/b230653709734b07b98186d88464f309
Autor:
Monica Baiula, Alberto Caligiana, Andrea Bedini, Junwei Zhao, Federica Santino, Martina Cirillo, Luca Gentilucci, Daria Giacomini, Santi Spampinato
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Age-related macular degeneration (AMD) is a complex multifactorial degenerative disease that leads to irreversible blindness. AMD affects the macula, the central part of the retina responsible for sharp central vision. Retinal pigment epithelium (RPE
Externí odkaz:
https://doaj.org/article/b3224316dacc481b886949952b698e7b
Autor:
Andrea Bedini, Lorenzo Di Cesare Mannelli, Laura Micheli, Monica Baiula, Gabriela Vaca, Rossella De Marco, Luca Gentilucci, Carla Ghelardini, Santi Spampinato
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Kappa opioid receptor (KOPr) agonists represent alternative analgesics for their low abuse potential, although relevant adverse effects have limited their clinical use. Functionally selective KOPr agonists may activate, in a pathway-specific manner,
Externí odkaz:
https://doaj.org/article/c5745159e6ba41cc97ba48ac3f15a654
Autor:
Monica Baiula, Roberto Greco, Lucia Ferrazzano, Alberto Caligiana, Klarida Hoxha, Daniele Bandini, Pasquale Longobardi, Santi Spampinato, Alessandra Tolomelli
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237746 (2020)
In recent years, several studies suggested that the ability of hyperbaric oxygen therapy (HBOT) to promote healing in patients with diabetic ulcers and chronic wounds is due to the reduction of inflammatory cytokines and to a significant decrease in
Externí odkaz:
https://doaj.org/article/8253affc5fe14eab87a3bd9adc061688
Autor:
Michele Anselmi, Monica Baiula, Federica Santino, Junwei Zhao, Santi Spampinato, Natalia Calonghi, Luca Gentilucci
Publikováno v:
Biomedicines, Vol 9, Iss 11, p 1737 (2021)
Arg-Gly-Asp (RGD)-binding integrins, e.g., αvβ3, αvβ1, αvβ5 integrins, are currently regarded as privileged targets for the delivery of diagnostic and theranostic agents, especially in cancer treatment. In contrast, scarce attention has been pa
Externí odkaz:
https://doaj.org/article/faf7fdc793aa4313b46478b618b4081c
Autor:
Andrea Sartori, Kelly Bugatti, Elisabetta Portioli, Monica Baiula, Irene Casamassima, Agostino Bruno, Francesca Bianchini, Claudio Curti, Franca Zanardi, Lucia Battistini
Publikováno v:
Molecules, Vol 26, Iss 19, p 6066 (2021)
Integrin α4β1 belongs to the leukocyte integrin family and represents a therapeutic target of relevant interest given its primary role in mediating inflammation, autoimmune pathologies and cancer-related diseases. The focus of the present work is t
Externí odkaz:
https://doaj.org/article/166aa7c11f0a4b829f71def7b9ba5c9c
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Among the other members of the adhesion molecules' family, α4β1 integrin, a heterodimeric receptor, plays a crucial role in inflammatory diseases, cancer development, metastasis and stem cell mobilization or retention. In many cases, its function i
Externí odkaz:
https://doaj.org/article/091caf53eedb4e9184a272f89331c577
Autor:
Michele Anselmi, Monica Baiula, Santi Spampinato, Roberto Artali, Tingting He, Luca Gentilucci
Publikováno v:
Journal of Medicinal Chemistry. 66:5021-5040
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e8667fbc086fb74976909f64ba36f3a
https://doi.org/10.1021/acs.jmedchem.2c02098
https://doi.org/10.1021/acs.jmedchem.2c02098
Autor:
Gentilucci, Monica Baiula, Michele Anselmi, Francesco Musiani, Alessia Ghidini, Jacopo Carbone, Alberto Caligiana, Andrea Maurizio, Santi Spampinato, Luca
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9588
Integrin receptors mediate cell–cell interactions via the recognition of cell-adhesion glycoproteins, as well as via the interactions of cells with proteins of the extracellular matrix, and upon activation they transduce signals bi-directionally ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::3c162184c0f62b742e985078978fbf10