Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Monica Akula"'
Autor:
Shannon M. McNamee, Monica Akula, Zoe Love, Neelaab Nasraty, Kaden Nystuen, Pushpendra Singh, Arun K. Upadhyay, Margaret M. DeAngelis, Neena B. Haider
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Retinitis Pigmentosa is a leading cause of severe vision loss. Retinitis Pigmentosa can present with a broad range of phenotypes impacted by disease age of onset, severity, and progression. This variation is influenced both by different gene
Externí odkaz:
https://doaj.org/article/760fb0df93694cf99cd9a1e2ee8b751e
Publikováno v:
Bioengineering, Vol 11, Iss 2, p 179 (2024)
Ocular diseases present a unique challenge and opportunity for therapeutic development. The eye has distinct advantages as a therapy target given its accessibility, compartmentalization, immune privilege, and size. Various methodologies for therapeut
Externí odkaz:
https://doaj.org/article/fd56c8305f874fadb70a162095cc027e
Autor:
Kaden L. Nystuen, Shannon M. McNamee, Monica Akula, Kristina M. Holton, Margaret M. DeAngelis, Neena B. Haider
Publikováno v:
Bioengineering, Vol 11, Iss 1, p 45 (2024)
Alzheimer’s Disease (AD) is a complex neurodegenerative disease resulting in progressive loss of memory, language and motor abilities caused by cortical and hippocampal degeneration. This review captures the landscape of understanding of AD patholo
Externí odkaz:
https://doaj.org/article/bf3971ef913347aeafe2a1c4a2737b76
Autor:
Vanessa B. Martino, Thomas Sabljic, Paula Deschamps, Rebecca M. Green, Monica Akula, Erica Peacock, Alexander Ball, Trevor Williams, Judith A. West-Mays
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 8, Pp 849-861 (2016)
Anterior segment dysgenesis (ASD) encompasses a group of developmental disorders in which a closed angle phenotype in the anterior chamber of the eye can occur and 50% of patients develop glaucoma. Many ASDs are thought to involve an inappropriate pa
Externí odkaz:
https://doaj.org/article/4cdfc075073c4fa58b4f0cbdb6e77bdf
Autor:
Anthony Saraco, Trevor Williams, Aftab Taiyab, Alexander K. Ball, Paula Deschamps, Monica Akula, Judith A. West-Mays
Publikováno v:
Curr Eye Res
PURPOSE: Our lab has shown that conditionally disrupting the transcription factor activating protein 2β (Tfap2b) gene, responsible for the activating protein-2β (AP-2β) transcription factor, exclusively in cranial neural crest cells (AP-2β NCC KO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d7aface918af82037902d70cfc6465e
https://pubmed.ncbi.nlm.nih.gov/33689532
https://pubmed.ncbi.nlm.nih.gov/33689532
Autor:
Monica Akula, Judith A. West-Mays, Paula Deschamps, Shannin Yee, Aftab Taiyab, Alexander K. Ball, Trevor Williams
Publikováno v:
Exp Eye Res
Previously, we have shown that Tfap2b, the gene encoding transcription factor AP-2β, is needed for normal mouse eye development. Specifically, targeted loss of Tfap2b in neural crest cells (NCCs)(1) and their derivatives, particularly the periocular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bae4305c9b65e6ed016a5643fd5f8f0
https://pubmed.ncbi.nlm.nih.gov/32353428
https://pubmed.ncbi.nlm.nih.gov/32353428
Publikováno v:
Journal of Neuroscience Research. 97:7-15
Development of the eye is closely associated with neural crest cell migration and specification. Eye development is extremely complex, as it requires the working of a combination of local factors, receptors, inductors, and signaling interactions betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5595bdf1ae71ecbdabd2cba06e73307
https://doi.org/10.1002/jnr.24245
https://doi.org/10.1002/jnr.24245
Publikováno v:
Exp Eye Res
The cornea is a highly specialized transparent tissue located at the anterior most surface of the eye. It consists of three main layers, the outer stratified squamous epithelium, the inner endothelium, and the intermediate stroma. Formation of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cffd8b63171fc29970f4d8457e3de420
https://doi.org/10.1016/j.exer.2020.108231
https://doi.org/10.1016/j.exer.2020.108231
Autor:
Erica Peacock, Rebecca M. Green, Thomas F. Sabljic, Trevor Williams, Vanessa Martino, Alexander K. Ball, Judith A. West-Mays, Monica Akula, Paula Deschamps
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 8, Pp 849-861 (2016)
Disease Models & Mechanisms
Disease Models & Mechanisms
Anterior segment dysgenesis (ASD) encompasses a group of developmental disorders in which a closed angle phenotype in the anterior chamber of the eye can occur and 50% of patients develop glaucoma. Many ASDs are thought to involve an inappropriate pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab94acdfcb94a6bb33e1b2cd265156a
https://doi.org/10.1242/dmm.025262
https://doi.org/10.1242/dmm.025262