Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Monica Singer"'
Publikováno v:
2018 ASEE Annual Conference & Exposition Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e1ccd2448b0672f824cdba3c46f5df1
https://doi.org/10.18260/1-2--29922
https://doi.org/10.18260/1-2--29922
Publikováno v:
2018 ASEE Annual Conference & Exposition Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8854c8b09877123712d801bd4f17581
https://doi.org/10.18260/1-2--30204
https://doi.org/10.18260/1-2--30204
Autor:
Erio Barale, Katia Karalis, Riccardo Barrile, Kyung-Jin Jang, Monica Singer, Abhishek Srivastava, Anna Herland, Josiah Sliz, Barry Jones, Hyoungshin Park, Janna Nawroth, Geraldine A. Hamilton, Dominic P. Williams, Wing W. Lam, Gauri Kulkarni, Jonathan E. Rubins, Suzzette Haney, Linda C. Andersson, Manisha Sonee, Konstantia Kodella, Debora B. Petropolis, Monicah A. Otieno, Heng-Keang Lim, Lorna Ewart, Bhanu Singh, Carl L. Manthey, Janey Ronxhi, Donald E. Ingber, David Conegliano, Anthony J. Streeter, Damir Simic
Nonclinical rodent and non-rodent toxicity models used to support clinical trials of candidate drugs may produce discordant results or fail to predict complications in humans contributing to drug failures in the clinic. Here we applied microengineere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77153c2fec6be0820279936c4ea70992
Autor:
Bhanu Singh, Suzzette Haney, Carl L. Manthey, Riccardo Barrile, Anna Herland, Dominic P. Williams, Manisha Sonee, Katia Karalis, Monica Singer, David Conegliano, Heng-Keang Lim, Geraldine A. Hamilton, Donald E. Ingber, Monicah A. Otieno, Anthony J. Streeter, Lorna Ewart, Erio Barale, Linda C. Andersson, Barry Jones, Wing W. Lam, Damir Simic, Konstantia Kodella, Debora B. Petropolis, Josiah Sliz, Janey Ronxhi, Janna Nawroth, Abhishek Srivastava, Kyung-Jin Jang, Gauri Kulkarni, Hyoungshin Park, Jonathan E. Rubins
Publikováno v:
Science translational medicine. 11(517)
Nonclinical rodent and nonrodent toxicity models used to support clinical trials of candidate drugs may produce discordant results or fail to predict complications in humans, contributing to drug failures in the clinic. Here, we applied microengineer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e12fac7c745aecb2cdd286e4f142c77
https://pubmed.ncbi.nlm.nih.gov/31776474
https://pubmed.ncbi.nlm.nih.gov/31776474
Autor:
Wim Bert Griet Schepens, Gilles Bignan, Leo Luistro, Sally Mahady, Monica Singer, Jocelyn Sendecki, Peter J. Connolly, James P. Edwards, Liam Campion, Kathryn Packman, Jan Willem Thuring, Hayley Ta, Nancy Bogdan, Shefali Patel, Caitlin Morgan, Daniel Jason Krosky, Emily Pierson, Glenn Van Aller, Melissa Smith, Thomas Wilde, Monicah A. Otieno, Michael J. Allegrezza, Heng-Keang Lim, Diana Wiley, Szeman Ruby Chan, Kim Staquet, Stuart L. Emanuel
Publikováno v:
Cancer Research. 80:5567A-5567A
The Stimulator of Interferon Genes (STING) protein is a key mediator of innate immunity that plays a central role in the immune response to invading pathogens (bacterial, viral) and transformed cells. A next generation human STING agonist, JNJ-‘619
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07931370687a649935a23154b8af8420
https://doi.org/10.1158/1538-7445.am2020-5567a
https://doi.org/10.1158/1538-7445.am2020-5567a
Publikováno v:
2017 ASEE Annual Conference & Exposition Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2251f2f9bb974f2b992bd2dca26bfcf8
https://doi.org/10.18260/1-2--28244
https://doi.org/10.18260/1-2--28244
Publikováno v:
Homo : internationale Zeitschrift fur die vergleichende Forschung am Menschen. 69(5)
This paper examines the role of the history of medicine in case of congenital isolated hemihyperplasia. Isolated hemihyperplasia is a genetic disorder in which one side of the body grows more than the other, causing visible lateral asymmetry of the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e893c648fadc1119cfc15ea923884288
https://pubmed.ncbi.nlm.nih.gov/30219584
https://pubmed.ncbi.nlm.nih.gov/30219584
Autor:
Tara Mezzasalma Haarlander, Karen Carroll, Sharon L. Burke, Shariff Bayoumy, Ingrid Christa Deckman, Cuifen Huo, Richard Alexander, Monica Singer, Matthew J. Todd, Yue-Mei Zhang, Kristi A. Leonard, Cindy Milligan, Robyn Williams, Kenneth J. Rhodes, Robert H. Scannevin, Keli Dzordzorme, John Spurlino, Brett A. Tounge, Diane M. Maguire, Paul F. Jackson, Celine Schalk-Hihi, Lawrence C. Kuo, Eric Devine, Frank A. Lewandowski
Publikováno v:
The Journal of biological chemistry. 292(43)
Aberrant activation of matrix metalloproteinases (MMPs) is a common feature of pathological cascades observed in diverse disorders, such as cancer, fibrosis, immune dysregulation, and neurodegenerative diseases. MMP-9, in particular, is highly dynami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7e2f60e01bada9e1e4fd469d2a6f02
https://pubmed.ncbi.nlm.nih.gov/29079642
https://pubmed.ncbi.nlm.nih.gov/29079642
Autor:
Peter Taggart, Jean McCarthy, S. Jim Proctor, Erin Saleh, L. Mark Kao, Angelique M. Leone, Lynn Varacallo, Michael K. McMillian, Kelley Michael F, Monica Singer
Publikováno v:
Advances in Bioscience and Biotechnology. :216-229
Idiosyncratic hepatotoxicity accounts for many drug failures in the clinic and is a leading cause for black-boxed and withdrawn drugs. This toxicity has proven difficult to predict preclinically, but correlates with oxidative stress/reactive metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cacd99a424d46f4fdc2628d0f4bc7c0
https://doi.org/10.4236/abb.2014.53028
https://doi.org/10.4236/abb.2014.53028
Autor:
W. Lam, Monica Singer, Heng-Keang Lim, Gauri Kulkarni, Monicah A. Otieno, Konstantia Kodella, Janey Ronxhi, Debora B. Petropolis, J. Chen, P. Guzzie-Peck, Damir Simic, Jonathan E. Rubins, K. Karalis, Kyung-Jin Jang, Geraldine A. Hamilton
Publikováno v:
Toxicology Letters. 295:S129-S130
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8915932a9b9c36ec1c9d05a2b896334f
https://doi.org/10.1016/j.toxlet.2018.06.691
https://doi.org/10.1016/j.toxlet.2018.06.691