Výsledky vyhledávání - "Monica, Stavarachi"

Potential association of obesity with IL6 G-174C polymorphism and TTV infections

Autor: Monica Stavarachi, Sonia Spandole, Oana Schiopu, I. Radu, P. Apostol, M. Toma, D. Cimponeriu, Lavinia Rusu, Anne Marie Craciun, Cristian Serafinceanu, Daniela Adriana Ion, Panduru Nicolae

Publikováno v: Open Life Sciences, Vol 8, Iss 7, Pp 625-632 (2013)

Polymorphisms in IL6, ACE and ATR genes are associated with obesity. Torque Teno virus (TTV) seems to be able to interfere with production of some proinflammatory cytokines associated with obesity and related phenotypes. The aim of this study was to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e714db74320d17641a36b02026ab454c
https://doi.org/10.2478/s11535-013-0178-1

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Thymidylate synthase (TS) tandem repeat promoter polymorphism and susceptibility to colorectal cancer of romanian subjects

Autor: Mihai TOMA, Monica STAVARACHI, Dănuţ CIMPONERIU, Pompilia APOSTOL, Traean BURCOŞ, Emil POPA, Nicolae PANDURU, Irina RADU, Lucian GAVRILĂ

Publikováno v: Analele Universitatii din Oradea: Fascicula Biologie, Vol TOM XVII, Iss 1, Pp 196-199 (2010)

The risk of colorectal cancer (CRC) is influence by polymorphisms located in the genes encoding enzymes of the folate pathway. The aim of this study was to evaluate if 2R/3R TS (rs34743033) polymorphism is involved in predisposition for colorectal in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::f8f983d13eff76fcf204a2b55e9aaea4

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Preliminary Results in a Study Regarding the Relationship Between Perlecan Gene Polymorphism and Spinal Muscular Atrophy Type I Disease

Autor: Niculina Butoianu, Monica Stavarachi, L. Gavrila, M. Toma

Publikováno v: Genetic Testing and Molecular Biomarkers. 13:821-824

Spinal muscular atrophy (SMA) is a neuromuscular disease characterized by weakness and atrophy of proximal muscles. Despite the fact that the disease transmission suggests an autosomal recessive trait, the wide spectrum of clinical manifestations ind

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::027f86d6e4bedb0b45ba62fad9ab90f9
https://doi.org/10.1089/gtmb.2009.0086

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Possible implication of LECAM-1 gene P213S polymorphism in the risk for advanced stages of diabetic nephropathy in patients with type 1 diabetes

Autor: Nicolae Mircea PANDURU, Danut CIMPONERIU, Pompilia APOSTOL, Maria MOTA, Eugen MOTA, Monica STAVARACHI, Mihai TOMA, Irina RADU, Anne-Marie CRACIUN, Cristian SERAFINCEANU, Dan Mircea CHETA

Publikováno v: Analele Universitatii din Oradea: Fascicula Biologie, Vol TOM XVI, Iss 2, Pp 99-103 (2009)

Diabetic nephropathy has an unclarified pathogenesis, with multifactorial aetiology which includes metabolic and haemodynamic abnormalities, aberrant signaling of numerous cytokines or growth factors and genetic susceptibility. Inflammation and low b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::70a90f91f8437e9799370a39dc8a2840

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P53 and DCC polymorphisms and the risk for colorectal cancer in romanian patients – a preliminary study

Autor: Mihai TOMA, Monica STAVARACHI, Danut CIMPONERIU, Pompilia APOSTOL, Mihai COJOCARU, Laurentiu BELUSICA, Nicolae PANDURU, Irina RADU, Lucian GAVRILA

Publikováno v: Analele Universitatii din Oradea: Fascicula Biologie, Vol TOM XVI, Iss 2, Pp 162-165 (2009)

Inactivation of tumor suppressor genes p53 and DCC has been frequently observed in colorectal cancer. The aim of this case-control study was to test possible association between polymorphisms g.32008376A>G (rs714) of DCC gene and g.7175464A>G (rs1625

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::4c076667af94f4a1a189c06ce48e6a0d

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Novel genetic susceptibility loci for diabetic end-stage renal disease identified through robust naive Bayes classification

Publikováno v: Sambo, F, Malovini, A, Sandholm, N, Stavarachi, M, Forsblom, C, Mäkinen, V-P, Harjutsalo, V, Lithovius, R, Gordin, D, Parkkonen, M, Saraheimo, M, Thorn, L M, Tolonen, N, Wadén, J, He, B, Osterholm, A-M, Tuomilehto, J, Lajer, M, Salem, R M, McKnight, A J, Tarnow, L, Panduru, N M, Barbarini, N, Di Camillo, B, Toffolo, G M, Tryggvason, K, Bellazzi, R, Cobelli, C, Groop, P-H & GENIE Consortium 2014, ' Novel genetic susceptibility loci for diabetic end-stage renal disease identified through robust naive Bayes classification ', Diabetologia, vol. 57, no. 8, pp. 1611-22 . https://doi.org/10.1007/s00125-014-3256-2

AIMS/HYPOTHESIS: Diabetic nephropathy is a major diabetic complication, and diabetes is the leading cause of end-stage renal disease (ESRD). Family studies suggest a hereditary component for diabetic nephropathy. However, only a few genes have been a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9bd2b443ecf9a5c6a2047765e3b1d3
http://hdl.handle.net/11577/2832100

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Phosphatidylinositol 3-kinase p85 regulatory subunit gene and spinal muscular atrophy disease

Autor: Monica STAVARACHI, Mihai TOMA, Pompilia APOSTOL, Danut CIMPONERIU, Irina RADU, Nicolae Mircea PANDURU, Niculina BUTOIANU, Lucian GAVRILA

Publikováno v: Analele Universitatii din Oradea: Fascicula Biologie, Vol TOM XVI, Iss 2, Pp 135-137 (2009)

Spinal muscular atrophy (SMA) is a frequent neuromuscular disorder caused by motoneuronal apoptosis, as a result of SMN (Survival Motor Neuron) protein deficiency. Although the SMA determining gene was identified, the molecular mechanism of the disea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::6b0ef3967c088e3531acab17c9616537

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Detection of possible restriction sites for type II restriction enzymes in DNA sequences

Autor: P, Gagniuc, D, Cimponeriu, C, Ionescu-Tîrgovişte, Andrada, Mihai, Monica, Stavarachi, T, Mihai, L, Gavrilă

Publikováno v: Romanian journal of internal medicine = Revue roumaine de medecine interne. 49(2)

In order to make a step forward in the knowledge of the mechanism operating in complex polygenic disorders such as diabetes and obesity, this paper proposes a new algorithm (PRSD -possible restriction site detection) and its implementation in Applied

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::40ad682d940f37f2450504b414cd07b0
https://pubmed.ncbi.nlm.nih.gov/22303603

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GWAS of Diabetic Nephropathy: Is the GENIE out of the Bottle?

Autor: Daniel B. Mirel, Kustaa Hietala, Markku Lehto, Ronan Roussel, Denise M. Sadlier, Andrew M. Taylor, Geoffrey V. Gill, Lena M. Thorn, Samy Hadjadj, David-Alexandre Trégouët, Markku Saraheimo, François Alhenc-Gelas, Bing He, Harvest F. Gu, Sarah L. Prior, Alexander P. Maxwell, Nina Tolonen, Maria Lajer, Anne-May Österholm, Eoin P. Brennan, Finian Martin, Andrew D. Paterson, Nicolae Mircea Panduru, Daryl Waggott, Winfred W. Williams, Benjamin J. Keller, Robert G. Nelson, Maija Parkkonen, Outi Heikkilä, Gianpaolo Zerbini, Jenny Söderlund, Anna Möllsten, Vincent Rigalleau, David A. Savage, Harshal Deshmukh, Daniel Gordin, Hans-Henrik Parving, Helen M. Colhoun, Emma Ahlqvist, Kerstin Brismar, Catherine Godson, Janne Pitkäniemi, Silvia Maestroni, Cameron D. Palmer, Pierre Lefebvre, Johan Wadén, Eugen Mota, Cinzia Sarti, Shelley B. Bull, Gareth J. McKay, Monica Stavarachi, Anna Syreeni, Raija Lithovius, Tamara Isakova, Anna Maestroni, Emma Fagerholm, Jose C. Florez, Leif Groop, Per-Henrik Groop, Janne P. Kytö, Henrik Falhammar, Robert L. Hanson, D. Cimponeriu, Lise Tarnow, Niina Sandholm, Cristian Serafinceanu, Heikki O. Tikkanen, Aino Soro-Paavonen, Candace Guiducci, Carol Forsblom, Elizabeth Swan, Päivi Lahermo, Claes Ladenvall, Michel Marre, Mihai Ioana, Maria Mota, Milla Rosengård-Bärlund, Karl Tryggvason, Andrew P. Boright, Matthias Kretzler, Valma Harjutsalo, Aila J. Ahola, Ville-Petteri Mäkinen, Peter Rossing, Rany M. Salem, Amy Jayne McKnight, Stephen C. Bain, Jaakko Tuomilehto, S. Mohsen Hosseini, Huateng Huang, Joel N. Hirschhorn, Tianwei Gu

Publikováno v: PLoS Genetics; 8(9) (2012)
PLoS Genetics
PLoS Genetics; Vol 8
PLoS Genetics, Vol 8, Iss 9, p e1002921 (2012)
Sandholm, N, Salem, R M, McKnight, A J, Brennan, E P, Forsblom, C, Isakova, T, McKay, G J, Williams, W W, Sadlier, D M, Mäkinen, V-P, Swan, E J, Palmer, C, Boright, A P, Ahlqvist, E, Deshmukh, H A, Keller, B J, Huang, H, Ahola, A J, Fagerholm, E, Gordin, D, Harjutsalo, V, He, B, Heikkilä, O, Hietala, K, Kytö, J, Lahermo, P, Lehto, M, Lithovius, R, Osterholm, A-M, Parkkonen, M, Pitkäniemi, J, Rosengård-Bärlund, M, Saraheimo, M, Sarti, C, Söderlund, J, Soro-Paavonen, A, Syreeni, A, Thorn, L M, Tikkanen, H, Tolonen, N, Tryggvason, K, Tuomilehto, J, Wadén, J, Gill, G V, Prior, S, Guiducci, C, Mirel, D B, Taylor, A, Savage, D A, Maxwell, A P & DCCT/EDIC Research Group 2012, ' New susceptibility Loci associated with kidney disease in type 1 diabetes ', PLoS Genetics, vol. 8, no. 9, e1002921, pp. e1002921 . https://doi.org/10.1371/journal.pgen.1002921

Diabetic kidney disease, or diabetic nephropathy (DN), is a major complication of diabetes and the leading cause of end-stage renal disease (ESRD) that requires dialysis treatment or kidney transplantation. In addition to the decrease in the quality

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c947d29d7b6f566def2e44b4b787e0
https://lup.lub.lu.se/record/3287820

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