Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Monica, Mantri"'
Autor:
Alexander Wolf, Monica Mantri, Muhammad Mukram Mohamed Mackeen, Heinrich Leonhardt, Christopher J. Schofield, Lothar Schermelleh, Astrid Heim, Benedikt M. Kessler, Erika Fichter, Angelika Böttger, Catherine Vénien-Bryan, Udo Müller, Gregory Dadie
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2013, 453, pp.357-370. ⟨10.1042/BJ20130529⟩
Biochemical Journal, 2013, 453, pp.357-370. ⟨10.1042/BJ20130529⟩
Biochemical Journal, Portland Press, 2013, 453, pp.357-370. ⟨10.1042/BJ20130529⟩
Biochemical Journal, 2013, 453, pp.357-370. ⟨10.1042/BJ20130529⟩
International audience; Jmjd6 (jumonji-domain-containing protein 6) is an Fe(II)- and 2OG (2-oxoglutarate)-dependent oxygenase that catalyses hydroxylation of lysine residues in proteins involved in premRNA splicing. Jmjd6 plays an essential role in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7c7cd0cc155d2525ab158f32ffa0ad
https://doi.org/10.1042/bj20130529
https://doi.org/10.1042/bj20130529
Autor:
Celia J. Webby, Michael A. McDonough, Eleanor A.L. Bagg, T. Krojer, Kathryn L. Kavanagh, Danica Butler, Christopher J. Schofield, Monica Mantri, Grazyna Kochan, Udo Oppermann
Lysyl and prolyl hydroxylations are well-known post-translational modifications to animal and plant proteins with extracellular roles. More recent work has indicated that the hydroxylation of intracellular animal proteins may be common. JMJD6 catalys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1f144cb15e40f628abb21964256b143
https://doi.org/10.1016/j.jmb.2010.05.054
https://doi.org/10.1016/j.jmb.2010.05.054
Publikováno v:
FEBS Journal. 279:1563-1575
Ferrous iron and 2-oxoglutarate-dependent oxygenases and related enzymes catalyse a range of oxidative reactions, possibly the widest of any enzyme family. Their catalytic flexibility is proposed to be related to their nonhaem iron-binding site, whic
Autor:
Monica Mantri, Nikita D. Loik, Christopher J. Schofield, Timothy D. W. Claridge, James S. O. McCullagh, Refaat B. Hamed
Publikováno v:
Chembiochem : a European journal of chemical biology. 12(4)
Amino acid analyses reveal that JMJD6-catalysed hydroxylation of RNA-splicing regulatory protein fragments occurs to give hydroxylysine products with 5S stereochemistry. This contrasts with collagen lysyl hydroxylases, which give 5R-hydroxylated prod
Autor:
Olivier de Graaf, Jacobien K. Von Frijtag Drabbe Künzel, Margot W. Beukers, Monica Mantri, Jacobus P. D. van Veldhoven, Regina Link, Johannes Brussee, Henk de Vries, Thea Mulder-Krieger, Adriaan P. IJzerman, Anikó Göblyös
Publikováno v:
Journal of medicinal chemistry. 51(15)
A 2A adenosine receptor antagonists usually have bi- or tricyclic N aromatic systems with varying substitution patterns to achieve desired receptor affinity and selectivity. Using a pharmacophore model designed by overlap of nonxanthine type of previ
Autor:
Monica Mantri, Olivier de Graaf, Jacobus van Veldhoven, Anikó Göblyös, Jacobien K. von Frijtag Drabbe Künzel, Thea Mulder-Krieger, Regina Link, Henk de Vries, Margot W. Beukers, Johannes Brussee, Adriaan P. IJzerman
Publikováno v:
Journal of Medicinal Chemistry; Jul2008, Vol. 51 Issue 15, p4449-4455, 7p