Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Monica, Acosta"'
Autor:
J. Silvio Gutkind, Andrew E. Aplin, Takami Sato, Jonathan A. Pachter, Prashant Mali, Glenn Merlino, Chi-Ping Day, Kyle Ford, Xingyu Wu, Silvia Coma, Manoela Tiago, Nadia Arang, Frederico Gomes, Simone Lubrano, Ayush Kishore, Robert Saddawi-Konefka, Monica Acosta, Justine S. Paradis
Supplementary Figure S4. MEKi/FAKi combination reduces B2905 syngeneic cells growth in allograft tumor models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::376bd239a291230f0640602beebf5692
https://doi.org/10.1158/1078-0432.22478109
https://doi.org/10.1158/1078-0432.22478109
Autor:
J. Silvio Gutkind, Andrew E. Aplin, Takami Sato, Jonathan A. Pachter, Prashant Mali, Glenn Merlino, Chi-Ping Day, Kyle Ford, Xingyu Wu, Silvia Coma, Manoela Tiago, Nadia Arang, Frederico Gomes, Simone Lubrano, Ayush Kishore, Robert Saddawi-Konefka, Monica Acosta, Justine S. Paradis
Purpose:Uveal melanoma is the most common eye cancer in adults. Approximately 50% of patients with uveal melanoma develop metastatic uveal melanoma (mUM) in the liver, even after successful treatment of the primary lesions. mUM is refractory to curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6586666443c72d8c7650610b8c2c2ce1
https://doi.org/10.1158/1078-0432.c.6529851
https://doi.org/10.1158/1078-0432.c.6529851
Autor:
J. Silvio Gutkind, Andrew E. Aplin, Takami Sato, Jonathan A. Pachter, Prashant Mali, Glenn Merlino, Chi-Ping Day, Kyle Ford, Xingyu Wu, Silvia Coma, Manoela Tiago, Nadia Arang, Frederico Gomes, Simone Lubrano, Ayush Kishore, Robert Saddawi-Konefka, Monica Acosta, Justine S. Paradis
Supplementary figure S2. Isobologram analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488c894c5197a73ee3e502e59c68a8e5
https://doi.org/10.1158/1078-0432.22478115.v1
https://doi.org/10.1158/1078-0432.22478115.v1
Autor:
J. Silvio Gutkind, Andrew E. Aplin, Takami Sato, Jonathan A. Pachter, Prashant Mali, Glenn Merlino, Chi-Ping Day, Kyle Ford, Xingyu Wu, Silvia Coma, Manoela Tiago, Nadia Arang, Frederico Gomes, Simone Lubrano, Ayush Kishore, Robert Saddawi-Konefka, Monica Acosta, Justine S. Paradis
Supplementary figure S1. Synthetic lethality of FAK and ERK/MAPK pathway inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a403519c803d895983e8ab05e66b7d8
https://doi.org/10.1158/1078-0432.22478118.v1
https://doi.org/10.1158/1078-0432.22478118.v1
Autor:
J. Silvio Gutkind, Andrew E. Aplin, Takami Sato, Jonathan A. Pachter, Prashant Mali, Glenn Merlino, Chi-Ping Day, Kyle Ford, Xingyu Wu, Silvia Coma, Manoela Tiago, Nadia Arang, Frederico Gomes, Simone Lubrano, Ayush Kishore, Robert Saddawi-Konefka, Monica Acosta, Justine S. Paradis
Supplementary figure 3. MEKi/FAKi combination reduces UM cells growth in xenograft tumor models with limited toxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c87d8b7c0df2cca4b5fa678e28f4bd7
https://doi.org/10.1158/1078-0432.22478112.v1
https://doi.org/10.1158/1078-0432.22478112.v1
Autor:
Priya Bhardwaj, Neil M. Iyengar, Heba Zahid, Katharine M. Carter, Dong Jun Byun, Man Ho Choi, Qi Sun, Oleksandr Savenkov, Charalambia Louka, Catherine Liu, Phoebe Piloco, Monica Acosta, Rohan Bareja, Olivier Elemento, Miguel Foronda, Lukas E. Dow, Sofya Oshchepkova, Dilip D. Giri, Michael Pollak, Xi Kathy Zhou, Benjamin D. Hopkins, Ashley M. Laughney, Melissa K. Frey, Lora Hedrick Ellenson, Monica Morrow, Jason A. Spector, Lewis C. Cantley, Kristy A. Brown
Publikováno v:
Science Translational Medicine. 15
Obesity, defined as a body mass index (BMI) ≥ 30, is an established risk factor for breast cancer among women in the general population after menopause. Whether elevated BMI is a risk factor for women with a germline mutation in BRCA1 or BRCA2 is l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cc1a4a00424cf078078c436e4e40bcb
https://doi.org/10.1126/scitranslmed.ade1857
https://doi.org/10.1126/scitranslmed.ade1857
SUMMARYEvolvability is defined as the capacity of populations to generate adaptive variation that promotes evolution by natural selection1–4. Lineages in a fluctuating environment must rapidly adapt to different states of the environment to survive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eac171ec1167beb226f1c4e946c6eb38
https://doi.org/10.1101/2023.01.04.520634
https://doi.org/10.1101/2023.01.04.520634
Publikováno v:
Journal of Ophthalmology.
Purpose. Recent evidence has shown that retinal inflammation is a key player in diabetic retinopathy (DR) pathogenesis. To further understand and validate the metabolic biomarkers of DR, we investigated the effect of intravitreal proinflammatory cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78640da98a86c84a1b166b1dd7250b9c
Autor:
Priya Bhardwaj, Neil M. Iyengar, Heba Zahid, Katharine M. Carter, Dong Jun Byun, Man Ho Choi, Qi Sun, Oleksandr Savenkov, Charalambia Louka, Catherine Liu, Phoebe Piloco, Monica Acosta, Rohan Bareja, Olivier Elemento, Miguel Foronda, Lukas E. Dow, Sofya Oshchepkova, Dilip D. Giri, Michael Pollak, Xi Kathy Zhou, Benjamin D. Hopkins, Ashley M. Laughney, Melissa K. Frey, Lora Hedrick Ellenson, Monica Morrow, Jason A. Spector, Lewis C. Cantley, Kristy A. Brown
Obesity is an established risk factor for breast cancer among women in the general population after menopause. Whether elevated bodyweight is a risk factor for women with a germline mutation in BRCA1 or BRCA2 is less clear due to inconsistent finding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1d8588548adab87af8d85aea74cfe2b
https://doi.org/10.1101/2022.07.29.502090
https://doi.org/10.1101/2022.07.29.502090
Autor:
Andrew E. Aplin, Justine S. Paradis, J. Silvio Gutkind, Prashant Mali, Manoela Tiago, Robert Saddawi-Konefka, Monica Acosta, Xingyu Wu, Glenn Merlino, Chi-Ping Day, Nadia Arang, Takami Sato, Silvia Coma, Simone Lubrano, Jonathan A. Pachter, Kyle Ford, Frederico Gomes, Ayush Kishore
Publikováno v:
Clinical Cancer Research. 27:3190-3200
Purpose:Uveal melanoma is the most common eye cancer in adults. Approximately 50% of patients with uveal melanoma develop metastatic uveal melanoma (mUM) in the liver, even after successful treatment of the primary lesions. mUM is refractory to curre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2950f0ec722e7e87f259a559e3039db
https://doi.org/10.1158/1078-0432.ccr-20-3363
https://doi.org/10.1158/1078-0432.ccr-20-3363