Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Monia Rocco"'
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Data from Synergistic antitumor effect between vorinostat and topotecan in small cell lung cancer cells is mediated by generation of reactive oxygen species and DNA damage-induced apoptosis
Autor: Alfredo Budillon, Alessandro Desideri, Elena Di Gennaro, Silvia Castelli, Monia Rocco, Francesca Bruzzese
The topoisomerase-I (topo-I) inhibitor topotecan, derivative of camptothecin, is the only registered drug for relapsed small cell lung cancer (SCLC). The histone deacetylase inhibitor vorinostat has shown preclinical and clinical antitumor activities
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b841deea098ee9be62503aa0517979d
https://doi.org/10.1158/1535-7163.c.6531860
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4
Proteomic analysis identifies differentially expressed proteins after HDAC vorinostat and EGFR inhibitor gefitinib treatments in Hep-2 cancer cells
Autor: Assunta Gagliardi, Alessandra Leone, Elena Di Gennaro, Luca Bini, Francesca Bruzzese, Laura Bianchi, Biagio Pucci, Monia Rocco, Alessandro Armini, Michele Puglia, Alfredo Budillon, Anna Gimigliano
Publikováno v: PROTEOMICS. 11:3725-3742
Several solid tumors are characterized by poor prognosis and few effective treatment options, other than palliative chemotherapy in the recurrent/metastatic setting. Epidermal growth factor receptor (EGFR) has been considered an important anticancer
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9efde5b83d7f8c468951d996e65183
https://doi.org/10.1002/pmic.201100092
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5
HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT
Autor: Francesca Bruzzese, Geny Piro, Alessandra Leone, Monia Rocco, Michele Caraglia, Alfredo Budillon, Elena Di Gennaro, Carmine Carbone
Publikováno v: Journal of Cellular Physiology. 226:2378-2390
Potentiation of epidermal growth factor receptor (EGFR) inhibitors is required in squamous cell carcinoma of head and neck (SCCHN) to improve their therapeutic index. We demonstrated that the histone deacetylase inhibitor vorinostat in combination wi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f513fb7ab697beacca139770a223e116
https://doi.org/10.1002/jcp.22574
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6
Synergistic antitumor effect between vorinostat and topotecan in small cell lung cancer cells is mediated by generation of reactive oxygen species and DNA damage-induced apoptosis
Autor: Alessandro Desideri, Elena Di Gennaro, Silvia Castelli, Alfredo Budillon, Francesca Bruzzese, Monia Rocco
Publikováno v: Molecular Cancer Therapeutics. 8:3075-3087
The topoisomerase-I (topo-I) inhibitor topotecan, derivative of camptothecin, is the only registered drug for relapsed small cell lung cancer (SCLC). The histone deacetylase inhibitor vorinostat has shown preclinical and clinical antitumor activities
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da20d97384855366d8f31d45467af5f0
https://doi.org/10.1158/1535-7163.mct-09-0254
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7
Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways
Autor: Maria Rita Milone, Biagio Pucci, Alessandra Leone, Michele Caraglia, Maria I. Chianese, Renato Franco, Alfredo Budillon, Francesca Bruzzese, E. Di Gennaro, Monia Rocco, Daniele Santini, Claudio Arra, Chiara Ciardiello, Antonio Luciano
Publikováno v: Cell Death & Disease
Patients with advanced prostate cancer (PCa) and multiple myeloma (MM) have limited long-term responses to available therapies. The histone deacetylase inhibitor panobinostat has shown significant preclinical and clinical anticancer activity in both
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c08f278ee82ab44b79d74dbe727b4d
http://hdl.handle.net/11591/184192
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8
Modular organization of the Sulfolobus solfataricus mini-chromosome maintenance protein
Autor: Monia Rocco, Mariarita De Felice, Francesco Esposito, Mariarosaria De Falco, Mosè Rossi, Francesca M. Pisani, Luca Esposito, Biagio Pucci
Publikováno v: The Journal of biological chemistry
282 (2007): 12574–12582. doi:10.1074/jbc.M610953200
info:cnr-pdr/source/autori:Pucci B.; De Felice M.; Rocco M.; Esposito F.; De Falco M.; Esposito L.; Rossi M.; Pisani F.M./titolo:Modular organization of the Sulfolobus solfataricus mini-chromosome maintenance protein/doi:10.1074%2Fjbc.M610953200/rivista:The Journal of biological chemistry (Print)/anno:2007/pagina_da:12574/pagina_a:12582/intervallo_pagine:12574–12582/volume:282
Mini-chromosome maintenance (MCM) proteins form ring-like hexameric complexes that are commonly believed to act as the replicative DNA helicase at the eukaryotic/archaeal DNA replication fork. Because of their simplified composition with respect to t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f66f82e11e366f26b310048371c911
http://hdl.handle.net/11588/110373
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9
Accelerated bone mass senescence after hematopoietic stem cell transplantation
Autor: Bianca, Serio, Luca, Pezzullo, Raffaele, Fontana, Silvana, Annunziata, Rosa, Rosamilio, Maria Rosaria Sessa, Valentina Giudice, Idalucia, Ferrara, Monia, Rocco, Gennaro De Rosa, Patrizia, Ricci, Libuse, Tauchmanovà, Nunzia, Montuori, Carmine Selleri
Publikováno v: Europe PubMed Central
Translational Medicine @ UniSa
Università degli studi di Salerno-IRIS
Osteoporosis and avascular necrosis (AVN) are long-lasting and debilitating complications of hematopoietic stem cell transplantation (HSCT). We describe the magnitude of bone loss, AVN and impairment in osteogenic cell compartment following autologou
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c969dc4f7027e7a827758f8ba91ff186
http://europepmc.org/abstract/med/23905076
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