Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Mong-Heng Wang"'
Autor:
Liang-Huan Wu, Yu-Wen Cheng, Fan-Li Lin, Kai-Cheng Hsu, Mong-Heng Wang, Jing-Lun Yen, Tsung-Jen Wang, Tony Eight Lin, Yi-Chien Liu, Wei-Jan Huang, George Hsiao
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116538- (2024)
Glaucoma is considered a neurodegenerative disease characterized by progressive visual field defects that may lead to blindness. Although controlling intraocular pressure (IOP) is the mainstay of glaucoma treatment, some glaucoma patients have unmet
Externí odkaz:
https://doaj.org/article/1f572671db9b44c28ad07161acd206b1
Autor:
Fan-Li Lin, Yu-Wen Cheng, Li-Huei Chen, Jau-Der Ho, Jing-Lun Yen, Mong-Heng Wang, Tzong-Huei Lee, George Hsiao
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 158, Iss , Pp 114138- (2023)
Age-related macular degeneration (AMD) is the leading cause of low vision and blindness for which there is currently no cure. Increased matrix metalloproteinase-9 (MMP-9) was found in AMD and potently contributes to its pathogenesis. Resident microgl
Externí odkaz:
https://doaj.org/article/1a14de4ff8cf4dd28bd8ce199fc224fa
Autor:
Po-Jen Hsueh, Mong-Heng Wang, Che-Jen Hsiao, Chih-Kuang Chen, Fan-Li Lin, Shu-Hsien Huang, Jing-Lun Yen, Ping-Huei Tsai, Yueh-Hsiung Kuo, George Hsiao
Publikováno v:
Molecules, Vol 26, Iss 10, p 2970 (2021)
Intracerebral hemorrhage (ICH) is a devastating neurological disorder characterized by an exacerbation of neuroinflammation and neuronal injury, for which few effective therapies are available at present. Inhibition of excessive neuroglial activation
Externí odkaz:
https://doaj.org/article/abd4a2942c8d40b79dfd12e655b0c62f
Publikováno v:
Antioxidants, Vol 9, Iss 6, p 520 (2020)
Oxidative stress is an important factor to cause the pathogenesis of diabetic retinopathy (DR) because the retina has high vascularization and long-time light exposition. Cyclooxygenase (COX), lipoxygenase (LOX), and cytochrome P450 (CYP) enzymes can
Externí odkaz:
https://doaj.org/article/a2c3ad1cbadc4e648c393b17a3420ea9
Autor:
Jing-Shiun Jan, Chih-Hao Yang, Mong-Heng Wang, Fan-Li Lin, Jing-Lun Yen, Irene Hsieh, Maksim Khotimchenko, Tzong-Huei Lee, George Hsiao
Publikováno v:
Marine Drugs, Vol 17, Iss 6, p 360 (2019)
Activated human monocytes/macrophages, which increase the levels of matrix metalloproteinases (MMPs) and pro-inflammatory cytokines, are the essential mechanisms for the progression of sepsis. In the present study, we determined the functions and mec
Externí odkaz:
https://doaj.org/article/4052ed46e4f74ec1acd4c8034b42b4b4
Autor:
Luyun Wang, Yang Liu, Huamin Wang, Xun Liu, Jie Chen, Mong-Heng Wang, Jingfeng Wang, Hui Huang
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94400 (2014)
Inner medulla collecting duct (IMCD) cells are the key part for urinary concentration. Hypotonic stress may trigger apoptosis of IMCD cells and induce renal injury. Epoxyeicosatrienoic acids (EETs) play an important role in anti-apoptosis, but their
Externí odkaz:
https://doaj.org/article/be5ccceacd454c2a9580207a24e58b69
Autor:
Mong Heng Wang, Shu Hsien Huang, Jing Lun Yen, Fan Li Lin, Chih Kuang Chen, Ping Huei Tsai, Po Jen Hsueh, Che Jen Hsiao, Yueh-Hsiung Kuo, George Hsiao
Publikováno v:
Molecules, Vol 26, Iss 2970, p 2970 (2021)
Molecules
Volume 26
Issue 10
Molecules
Volume 26
Issue 10
Intracerebral hemorrhage (ICH) is a devastating neurological disorder characterized by an exacerbation of neuroinflammation and neuronal injury, for which few effective therapies are available at present. Inhibition of excessive neuroglial activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a10642d8e0263fd74edef1275781a0
https://www.mdpi.com/1420-3049/26/10/2970
https://www.mdpi.com/1420-3049/26/10/2970
Publikováno v:
Antioxidants, Vol 9, Iss 520, p 520 (2020)
Antioxidants
Antioxidants
Oxidative stress is an important factor to cause the pathogenesis of diabetic retinopathy (DR) because the retina has high vascularization and long-time light exposition. Cyclooxygenase (COX), lipoxygenase (LOX), and cytochrome P450 (CYP) enzymes can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d5d4ab4304d9fc60e55ddb04414eea
https://www.mdpi.com/2076-3921/9/6/520
https://www.mdpi.com/2076-3921/9/6/520
Autor:
Khaled Elmasry, Amany Tawfik, Nader Sheibani, Khaled A. Hussein, Mong Heng Wang, Mohamed El-Shafey, Babak Baban, Ahmed Ibrahim, Mohamed Al-Shabrawey, Heba Saleh
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1862:636-645
Aims Our previous studies have established a role for 12/15-lipoxygenase (LO) in mediating the inflammatory response in diabetic retinopathy (DR). However, the extent at which the local or systemic induction of 12/15-LO activity involved is unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b422fc7d9a53703e0a3f311b14e14e1
https://doi.org/10.1016/j.bbalip.2017.03.010
https://doi.org/10.1016/j.bbalip.2017.03.010
Publikováno v:
Diabetes. 68
Nearly all patients with type 1 diabetes and 60% of those with type 2 diabetes develop diabetic retinopathy (DR). Thus, there is an urgent need to identify new therapeutic targets to prevent or at least to minimize microvascular dysfunction associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::414afef618822d5638189cc9b4df9697
https://doi.org/10.2337/db19-46-or
https://doi.org/10.2337/db19-46-or