Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mong Sing Lai"'
Autor:
Chia-Yeh Lin, Meng-Ying Wu, Sophie Gay, Lisette Marjavaara, Mong Sing Lai, Wei-Chun Hsiao, Shih-Hsun Hung, Hsin-Yi Tseng, Duncan Edward Wright, Chen-Yi Wang, Guoo-Shyng W Hsu, Didier Devys, Andrei Chabes, Cheng-Fu Kao
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004667 (2014)
The influence of mono-ubiquitylation of histone H2B (H2Bub) on transcription via nucleosome reassembly has been widely documented. Recently, it has also been shown that H2Bub promotes recovery from replication stress; however, the underling molecular
Externí odkaz:
https://doaj.org/article/b555cbe6682248c2a67ae971a37e8637
Publikováno v:
Advances in experimental medicine and biology. 1042
Recent studies on G-quadruplex (G4) revealed crucial and conserved functions of G4 in various biological systems. We recently showed that Rif1, a conserved nuclear factor, binds to G4 present in the intergenic regions and plays a major role in spatio
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789811069543
Recent studies on G-quadruplex (G4) revealed crucial and conserved functions of G4 in various biological systems. We recently showed that Rif1, a conserved nuclear factor, binds to G4 present in the intergenic regions and plays a major role in spatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::044cf18dcd2331f870d3dfc4f9228f3a
https://doi.org/10.1007/978-981-10-6955-0_14
https://doi.org/10.1007/978-981-10-6955-0_14
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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DNA and RNA polymerases clash along the genome as they compete for the same DNA template. Cells have evolved specialized strategies to prevent and resolve replication and transcription interference. Here, we review the topology and architecture at si
Autor:
Lui Sato, Takemi Enomoto, Satoshi Kawashima, Mong Sing Lai, Masayuki Seki, Hirohito Endo, Masami Horikoshi
Publikováno v:
Genes to Cells. 15:945-958
Eukaryotic chromatin is regulated by chromatin factors such as histone modification enzymes, chromatin remodeling complexes and histone chaperones in a variety of DNA-dependent reactions. Among these reactions, transcription in the chromatin context
Publikováno v:
EMBO reports. 8:685-690
The Saccharomyces cerevisiae RecQ-mediated genome instability (Rmi1) protein was recently identified as the third member of the slow growth suppressor 1-DNA topoisomerase III (Sgs1-Top3) complex, which is required for maintaining genomic stability. H
Autor:
Hideaki Ogiwara, Kazuo Yamamoto, Shusuke Tada, Ayako Ui, Takemi Enomoto, Masayuki Seki, Mong Sing Lai
Publikováno v:
Biochemical and Biophysical Research Communications. 356:1031-1037
Unequal sister chromatid recombination (uSCR) is elevated in budding yeast sgs1 mutants, which lack a homolog of the human BLM gene that causes Bloom syndrome. Examination of the mechanism responsible for elevated uSCR in sgs1 mutants showed that mut
Publikováno v:
Biochemical and Biophysical Research Communications. 354:222-226
Deletion mutants of CHL1 or CTF4, which are required for sister chromatid cohesion, showed higher sensitivity to the DNA damaging agents methyl methanesulfonate (MMS), hydroxyurea (HU), phleomycin, and camptothecin, similar to the phenotype of mutant
Publikováno v:
Biochemical and biophysical research communications. 427(3)
Saccharomyces cerevisiae RecQ helicase (Sgs1) combines with DNA topoisomerase III (Top3) and RecQ-mediated genome instability 1 (Rmi1) to form an evolutionarily conserved complex that is required for processing homologous recombination intermediates
Autor:
Marco Foiani, Mong Sing Lai
Publikováno v:
Cell. 149(6)
The ATR and ATM checkpoint kinases preserve the integrity of replicating chromosomes by preventing the reversal of stalled and terminal replication forks. Hu et al. now show that the ATR pathway targets the Dna2 nuclease to process stalled forks and