Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Mong Shang Lin"'
Publikováno v:
Journal of Biological Chemistry. 294:6227-6239
Gcn5 and sirtuins are highly conserved histone acetyltransferase (HAT) and histone deacetylase (HDAC) enzymes that were first characterized as regulators of gene expression. Although histone tails are important substrates of these enzymes, they also
Gcn5 and sirtuins are highly conserved HAT and HDAC enzymes that were first characterised as regulators of gene expression. Although histone tails are important substrates of these enzymes, these proteins also target many non-histone substrates that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ff9a249246f77d8c993050e3dcf4fb
Autor:
Mukesh Kumar, Kailash C. Bhol, Mong-Shang Lin, Lisa A. Cavacini, Shih-Wei Yeh, Mark Duval, Marshall R. Posner, A. Razzaque Ahmed
Publikováno v:
Clinical Immunology. 120:68-75
Pemphigus vulgaris (PV) is a potentially fatal autoimmune mucocutaneous disease associated with production of IgG autoantibodies to desmoglein 3 (Dsg3), a 130-kDa epidermal cadherin protein. The binding of pathogenic antibody to Dsg3 on epidermal ker
Publikováno v:
Clinical Immunology. 116:54-64
Pemphigus vulgaris (PV) is an acquired immunobullous disorder. At the early stage of the disease (mucosal PV), patients display only autoimmunity to desmoglein (Dsg) 3 and develop mucosal blisters; while at the later stage of the disease (mucocutaneo
Publikováno v:
Journal of the American Academy of Dermatology. 51:118-122
Bullous pemphigoid (BP) and epidermolysis bullosa acquisita are distinct autoimmune blistering disorders. BP is characterized by autoantibodies directed against the NC16A domain of collagen XVII, whereas patients with epidermolysis bullosa acquisita
Publikováno v:
Journal of Investigative Dermatology. 121:1373-1378
Pemphigus foliaceus (PF) is an antibody-mediated autoimmune disorder with IgG1 and IgG4 as the predominant subclasses of autoantibodies against a desmosomal glycoprotein, desmoglein-1 (Dsg1). Previously, we found that the IgG4 anti-Dsg1 autoantibodie
Autor:
G. J. Giudice, Mong Shang Lin, Bahjat F. Qaqish, Luis A. Arteaga, Gunter Hans-Filho, Valeria Aoki, Simon Warren, Evandro A. Rivitti, Luis A. Diaz
Publikováno v:
Journal of Investigative Dermatology. 120:1-5
Endemic pemphigus foliaceus, like the sporadic form seen in the developed world, is mediated by IgG antibodies to desmoglein-1. We studied an endemic focus in Limao Verde, Brazil, where disease prevalence is 3.4%. We previously detected IgG antibodie
Publikováno v:
Clinical Immunology. 105:64-74
In this study we systematically characterized isotype profiles and antigenic and tissue specificity of antidesmoglein autoantibodies from patients with pemphigus foliaceus (PF) and pemphigus vulgaris (PV) using enzyme-linked immunoabsorbent assays (E
Autor:
Janet A. Fairley, Detlef Zillikens, Monica Olague-Marchan, Chang-Ling Fu, George J. Giudice, Mary K. Hacker, Mong-Shang Lin
Publikováno v:
Clinical Immunology. 102:310-319
Linear IgA bullous disease (LABD) is an autoimmune skin disease characterized by subepidermal blisters and IgA autoantibodies directed against the epidermal basement membrane zone (BMZ) of the skin. Various antigens have been identified as targets of
Autor:
Raymond G. Hoffmann, Luis A. Diaz, Simon Warren, Mong Shang Lin, Evandro A. Rivitti, George J. Giudice, Gunter Hans-Filho, Vandir dos Santos, Valeria Aoki
Publikováno v:
New England Journal of Medicine. 343:23-30
Background Pemphigus foliaceus is an autoimmune skin disease mediated by autoantibodies against desmoglein 1. The endemic form is thought to have an environmental cause. The Terena reservation of Limao Verde in Mato Grosso do Sul, Brazil, is a recent