Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Monde Ntwasa"'
Autor:
Samuel Nzekwe, Adetoun Morakinyo, Monde Ntwasa, Sogolo Lebelo, Oluwafemi Oguntibeju, Oluokun Oyedapo, Ademola Ayeleso
Publikováno v:
Phytomedicine Plus, Vol 4, Iss 4, Pp 100646- (2024)
Background: Oxidative stress is a disruption in the balance between free radicals and the body's natural defenses. This study investigated the modulatory effect of a flavonoid-rich fraction of Monodora tenuifolia seed (FRFMTS) on oxidative stress and
Externí odkaz:
https://doaj.org/article/85946cdbf5a0422788756fc977c2ce65
Autor:
Monde Ntwasa, Zodwa Dlamini
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/3e1e1711bc1843e6800a00cd71e9d580
Autor:
Monde Ntwasa
Publikováno v:
Cells, Vol 13, Iss 13, p 1124 (2024)
Hdm2 and Hdm4 are structural homologs that regulate the tumor suppressor protein, p53. Since some tumors express wild-type p53, Hdm2 and Hdm4 are plausible targets for anticancer drugs, especially in tumors that express wild-type p53. Hdm4 can enhanc
Externí odkaz:
https://doaj.org/article/ec25752bb2f0410fbb91a172a5d7f100
Autor:
Bonnie L Russell, Monde Ntwasa
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0277478 (2023)
RBBP6 is a 250 kDa eukaryotic protein known to be a negative regulator of p53 and essential for embryonic development. Furthermore, RBBP6 is a critical element in carcinogenesis and has been identified as a potential biomarker for certain cancers. RB
Externí odkaz:
https://doaj.org/article/9d7fb28b71fc446aa44768504a76e214
Autor:
Samuel Nzekwe, Adetoun Morakinyo, Monde Ntwasa, Oluwafemi Oguntibeju, Oluboade Oyedapo, Ademola Ayeleso
Publikováno v:
Metabolites, Vol 13, Iss 2, p 292 (2023)
Diabetes mellitus is a metabolic disorder caused by either the total destruction of the pancreatic beta cells that secrete insulin for the uptake of glucose from the circulation or as a result of the inability of body cells to respond to the presence
Externí odkaz:
https://doaj.org/article/a556c1d3a17d40a1823762a7cba289e1
Autor:
Mosebolatan Victoria Adegbola, Godwin Anyim, Monde Ntwasa, Ademola Olabode Ayeleso, Temitope Adenike Oyedepo
Publikováno v:
Applied Sciences, Vol 12, Iss 16, p 8216 (2022)
Artesunate toxicity has been linked to increased production of reactive oxygen species resulting in oxidative stress, which has been implicated in the pathogenesis of many chronic diseases. This study evaluated the effects of hydroethanolic extract o
Externí odkaz:
https://doaj.org/article/6acf0c9e247b4c4e8f52de9c32add338
Autor:
Bonnie L. Russell, Selisha A. Sooklal, Sibusiso T. Malindisa, Lembelani Jonathan Daka, Monde Ntwasa
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Through genetic and epigenetic alterations, cancer cells present the immune system with a diversity of antigens or neoantigens, which the organism must distinguish from self. The immune system responds to neoantigens by activating naïve T cells, whi
Externí odkaz:
https://doaj.org/article/3da468a5483c477ba483372036932357
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222614 (2019)
The Warburg Effect has emerged as a potential drug target because, in some cancer cell lines, it is sufficient to subvert it in order to kill cancer cells. It has also been shown that the Warburg Effect occurs in innate immune cells upon infection. I
Externí odkaz:
https://doaj.org/article/2d48633c25ae48c093bd4bfae185ae23
Autor:
Adugna Abdi Woldesemayat, Monde Ntwasa
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Drought alone or in combination with other stresses forms the major crop production constraint worldwide. Sorghum, one of the most important cereal crops is affected by drought alone or in combination with co-occurring stresses; notwithstanding, sorg
Externí odkaz:
https://doaj.org/article/28c3a98ea044475fa20a381e8c1fe34f
Autor:
Bernice Monchusi, Monde Ntwasa
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182789 (2017)
The Warburg Effect, characterized by increased rate of glycolysis even under normoxic conditions, is one of the hallmarks of cancer. Relatively lower oxidative phosphorylation (OXPHOS) is also a characteristic feature in cancer cells. We hypothesized
Externí odkaz:
https://doaj.org/article/2a4073568711437782e8c5ec50d3daf7