T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses

Autor: Ane Ogbe, Barbara Kronsteiner, Donal T. Skelly, Matthew Pace, Anthony Brown, Emily Adland, Kareena Adair, Hossain Delowar Akhter, Mohammad Ali, Serat-E Ali, Adrienn Angyal, M. Azim Ansari, Carolina V. Arancibia-Cárcamo, Helen Brown, Senthil Chinnakannan, Christopher Conlon, Catherine de Lara, Thushan de Silva, Christina Dold, Tao Dong, Timothy Donnison, David Eyre, Amy Flaxman, Helen Fletcher, Joshua Gardner, James T. Grist, Carl-Philipp Hackstein, Kanoot Jaruthamsophon, Katie Jeffery, Teresa Lambe, Lian Lee, Wenqin Li, Nicholas Lim, Philippa C. Matthews, Alexander J. Mentzer, Shona C. Moore, Dean J. Naisbitt, Monday Ogese, Graham Ogg, Peter Openshaw, Munir Pirmohamed, Andrew J. Pollard, Narayan Ramamurthy, Patpong Rongkard, Sarah Rowland-Jones, Oliver Sampson, Gavin Screaton, Alessandro Sette, Lizzie Stafford, Craig Thompson, Paul J. Thomson, Ryan Thwaites, Vinicius Vieira, Daniela Weiskopf, Panagiota Zacharopoulou, Oxford Immunology Network Covid-19 Response T Cell Consortium, Oxford Protective T Cell Immunology for COVID-19 (OPTIC) Clinical Team, Lance Turtle, Paul Klenerman, Philip Goulder, John Frater, Eleanor Barnes, Susanna Dunachie

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

Understanding the immune response to SARS-CoV-2 is dependent on being able to distinguish COVID-19 immune responses from cross-reactive immune responses to other coronaviruses. Here the authors show that choice of antigens and whether an ICS, ELISPOT

Externí odkaz: https://doaj.org/article/316bcccee68f41c8b075256474e98d3e

Characterization of Teicoplanin-Specific T-Cells from Drug Naïve Donors Expressing HLA-A*32:01

Autor: Joshua Gardner, Monday Ogese, Catherine J. Betts, Munir Pirmohamed, Dean J. Naisbitt

Publikováno v: Chemical research in toxicology

Teicoplanin is a glycopeptide antibiotic deployed to combat Gram-positive bacterial infection and has recently been associated with development of adverse drug reactions, particularly following previous exposure to vancomycin. In this study, we gener

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4796055ef9e0793a11c14e3ddc8c4050
https://doi.org/10.1021/acs.chemrestox.1c00425

Prospective observational study of SARS-CoV-2 infection, transmission and immunity in a cohort of households in Liverpool City Region, UK (COVID-LIV): a study protocol

Autor: Daniel Hungerford, Neil French, Carrol Gamble, Laura Marsh, Nigel A Cunliffe, Tracy Moitt, Miren Iturriza-Gómara, Chloe Donohue, William Greenhalf, Lance Turtle, Stephen Aston, Milton Ashworth, Laura Booth, Katie Bullock, Terry Foster, Joanna Middleton, William Reynolds, Victoria E Shaw, Eve Wilcock, Jane Armstrong, Susan Dobson, Ashley P Jones, Wega Setiabudi, Krishanthi Subramaniam, Natasha Marcella Vaselli, Moon Wilton, Gareth Platt, Dean J Naisbitt, Emily R Adams, Lynnette Crossley, Neil Joseph, Lee D Troughton, Samantha Kilada, Katharine Abba, Victoria Simpson, Lynsey Goodwin, Rachael Daws, Shiva S Forootan, Rachel Press, Vida Spaine, Lesley Hands, Kate Bradfield, Carol McNally, Silviya Balabanova, Lynsey Finnetty, Paul J Thomson, Monday Ogese, Kareena Adair, Liam Farrell, Kanoot Jaruthamsophon, Adam Lister, Benjamin W A Catterall, Lara Lavelle-Langham, Emily Cass, Alejandra Doce Carracedo, Lianne Davies, Lisa Flaherty, Melanie Oates, Nicole Maziere, Jennifer Lloyd, Hannah Massey, Anthony Holmes, Nicola Carlucci, Vanessa Brammah, Yasmyn Ramos, Daniel Allen, Debbie Howarth, Jena Lowe, Jayne Jones, Paula Wright, Iain Slack, Simone McLaughlin, Jessica Mason, Thomas Edwards, Claudia McKeown, Elysse Hendrick, Chris Williams, Rachel Byrne, Kate Buist, Gala Garrod, Sophie Owen, Efstathia Gkioni

Publikováno v: BMJ Open, Vol 11, Iss 3 (2021)
BMJ Open

IntroductionThe emergence and rapid spread of COVID-19 have caused widespread and catastrophic public health and economic impact, requiring governments to restrict societal activity to reduce the spread of the disease. The role of household transmiss

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88076a0c028a5cddc0ce6a0f810d595f
https://bmjopen.bmj.com/content/11/3/e048317.full

7th Drug hypersensitivity meeting: part two

Autor: Javier Dionicio Elera, Cosmin Boteanu, Maria Aranzazu Jimenez Blanco, Rosario Gonzalez-Mendiola, Irene Carrasco García, Antonio Alvarez, Jose Julio Laguna Martinez, Jaume Martí Garrido, Carla Torán Barona, Carolina Perales Chorda, Ramón López Salgueiro, Miguel Díaz Palacios, Dolores Hernández Fernández De Rojas, Emre Ali Acar, Ayse Aktas, Aylin Türel Ermertcan, Peyker Temiz, Chien-Yio Lin, Chung-Yee Rosaline Hui, Ya-Ching Chang, Chih-Hsun Yang, Wen-Hung Chung, Fabrícia Carolino, Diana Silva, Eunice Dias De Castro, Josefina R. Cernadas, Luis Felipe Ensina, Carolina Aranda, Ines Camelo Nunes, Alex Lacerda, Ana Maria Martins, Ekaterini Goudouris, Marcia Ribeiro, José Francisco Da Silva Franco, Leandra Queiroz, Dirceu Solé, Ceyda Tunakan Dalgiç, Aytül Zerrin Sin, Fatma Düsünür Günsen, Gökten Bulut, Fatma Ömür Ardeniz, Okan Gülbahar, Emine Nihal Mete Gökmen, Ali Kokuludag, Ana M. Montoro De Francisco, Talía Mª De Vicente Jiménez, Adriana M. Mendoza Parra, Angella M. Burgos Pimentel, Amelia García Luque, Luis Amaral, Leonor Carneiro Leão, Nicole Pinto, Joana Belo, João Marques, Pedro Carreiro-Martins, Paula Leiria-Pinto, Amel Chaabane, Haifa Ben Romdhane, Nadia Ben Fredj, Zohra Chadly, Naceur A. Boughattas, Karim Aouam, Astrid P. Uyttebroek, Chris H. Bridts, Antonino Romano, Didier G. Ebo, Vito Sabato, Anabela Lopes, Joana Cosme, Rita Aguiar, Tatiana Lourenço, Maria-João Paes, Amélia Spínola-Santos, Manuel Pereira-Barbosa, Cíntia Rito Cruz, Rute Pereira Dos Reis, Elza Tomaz, Ana Paula Pires, Filipe Inácio, Filipe Benito-Garcia, Inês Mota, Magna Correia, Ângela Gaspar, Marta Chambel, Susana Piedade, Mário Morais-Almeida, Alla Nakonechna, Yurij Antipkin, Tetiana Umanets, Fernando Pineda, Francisca Arribas, Volodymyr Lapshyn, Pablo Andrés Miranda, Bautista De La Cruz Hoyos, Aranzazu Jimenez Blanco, Marta Del Pozo, Alessandra Vultaggio, Francesca Nencini, Sara Pratesi, Andrea Matucci, Enrico Maggi, Ivana Cegec, Danica Juricic Nahal, Viktorija Erdeljic Turk, Matea Radacic Aumiler, Ksenija Makar Ausperger, Iva Kraljickovic, Iveta Simic, Yukie Yamaguchi, Tomoya Watanabe, Megumi Satoh, Tomohiko Tanegashima, Kayoko Oda, Hidefumi Wada, Michiko Aihara, Jaechun Jason Lee, Jay Chol Choi, Hwa Young Lee, Rosa-Anita Rodrigues Fernandes, Emília Faria, Joana Pita, Nuno Sousa, Carmelita Ribeiro, Isabel Carrapatoso, Ana Todo Bom, Ana Rodolfo, Eunice Dias-Castro, Marina Voronova, Diana Kury Valle, Verónica Pacheco Coronel, Carolina Perales Chordá, Roselle Catherine Yu Madamba, Marta Ferrer, Maria Jose Goikoetxea, Carmen D’Amelio, Amalia Bernad, Olga Vega, Gabriel Gastaminza, Beatriz Pola Bibián, Marina Lluncor Salazar, Gemma Vilà-Nadal, Ana María Fiandor Roman, Javier Dominguez Ortega, Miguel Gonzalez Muñoz, Santiago Quirce Gancedo, Maria Rosario Cabañas Moreno, Kathrin Scherer Hofmeier, Vladyslava Barzylovych, Beatriz Pola, Marina Lluncor, Ana Fiandor, Teresa Bellón, Javier Domínguez, Santiago Quirce, Min-Suk Yang, Sun-Sin Kim, Sae-Hoon Kim, Hye-Ryun Kang, Heung-Woo Park, Sang-Heon Cho, Kyung-Up Min, Yoon-Seok Chang, Clémence Delahaye, Jenny Flabbee, Julie Waton, Olivia Bauvin, Annick Barbaud, Najah Ben Fadhel, Sandra Jerkovic Gulin, Anca Chiriac, Bárbara Kong Cardoso, Regina Viseu, Ana Moreira, Susana Cadinha, Ana Castro Neves, Patrícia Barreira, Daniela Malheiro, J. P. Moreira Da Silva, Ružica Jurakic-Toncic, Suzana Ljubojevic, Petra Turcic, Liesbeth Gilissen, Sara Huygens, An Goossens, Inmaculada Andreu, Alicia Martinez Romero, Pau Gomez Cabezas, Pedro Ayuso Parejo, Maria Del Carmen Plaza-Serón, Inmaculada Doña, Natalia Blanca-López, Carlos Flores, María Luisa Galindo, Ana Molina, James Richard Perkins, José Antonio Cornejo-García, José Augusto García-Agúndez, Elena García-Martín, Paloma Campo, María Gabriela Canto, Miguel Blanca, Rosa María Guéant-Rodríguez, Raquel Jurado-Escobar, Esther Barrionuevo, María Salas, Gabriela Canto, Jean-Louis Guéant, Toru Usui, Arun Tailor, Lee Faulkner, John Farrell, Ana Alfirevic, B. Kevin Park, Dean J. Naisbitt, Oswaldo Trelles, María Auxiliadora Guerrero, Alex Upton, Mayumi Ueta, Hiromi Sawai, Chie Sotozono, Katushi Tokunaga, Shigeru Kinoshita, Chonlaphat Sukasem, Patompong Satapornpong, Therdpong Tempark, Pawinee Rerknimitr, Kulprapat Pairayayutakul, Jettanong Klaewsongkram, N. Koomdee, T. Jantararoungtong, S. Santon, A. Puangpetch, U. Intusoma, W. Tassaneeyakul, V. Theeramoke, Elena Ramirez, Alberto Manuel Borobia, Hoi Tong, Jose Luis Castañer, Francisco José De Abajo, Violeta Régnier Galvao, Rebecca Pavlos, Elizabeth Mckinnon, Kristina Williams, Alicia Beeghly-Fadiel, Alec Redwood, Elizabeth Phillips, Mariana Castells, Elisa Boni, Marina Russello, Marina Mauro, Kok Loong Ue, Krzysztof Rutkowski, Victor Soriano Gomis, Jorge Frances Ferre, Angel Esteban Rodriguez, Vicente Cantó Reig, Javier Fernandez Sanchez, Christine Breynaert, Erna Van Hoeyveld, Rik Schrijvers, Raquel Fuentes Irigoyen, Daniel Collado, Yolanda Vida, Francisco Najera, Ezequiel Perez-Inestrosa, Pablo Mesa-Antunez, Cristobalina Mayorga, María José Torres, Line K. Tannert, Charlotte G. Mortz, Per Stahl Skov, Carsten Bindslev-Jensen, Wolfgang Pfützner, Hannah Dörnbach, Johanna Visse, Michele Rauber, Christian Möbs, Abdelbaset A. Elzagallaai, Lindsey Chow, Awatif M. Abuzgaia, Michael J. Rieder, Jason Trubiano, Emily Woolnough, Kaija Stautins, Christina Cheng, Kenichi Kato, Hiroaki Azukizawa, Takaaki Hanafusa, Ichiro Katayama, Toshiharu Fujiyama, Hideo Hashizume, Takatsune Umayahara, Taisuke Ito, Yoshiki Tokura, Mira Silar, Mihaela Zidarn, Helena Rupnik, Peter Korosec, Alec James Redwood, Kaija Strautins, Katie White, Abha Chopra, Katherine Konvinse, Shay Leary, Simon Mallal, Rosario Cabañas, Ana María Fiandor, Andrew Sullivan, Paul Whitaker, Daniel Peckham, Wei Yann Haw, Marta E. Polak, Carolann Mcguire, Michael R. Ardern-Jones, Yumi Aoyama, Tetsuo Shiohara, Sara Correia, Asli Gelincik, Semra Demir, Fatma Sen, Hamza Ugur Bozbey, Muge Olgac, Derya Unal, Raif Coskun, Bahauddin Colakoglu, Suna Buyuozturk, Esin Çatin-Aktas, Gunnur Deniz, Jose Julio Laguna, J. Dionicio, Tahia Fernandez, I. Olazabal, Maria Dolores Ruiz, Maria José Torres, Alberto Lafuente, Jorge Núñez, Tahia Diana Fernández, Francisca Palomares, Rubén Fernández, Maria Isabel Sanchez, Tahía Fernandez, Arturo Ruiz, Adriana Ariza, Amalia Bernad Alonso, Carmen D’Amelio Garófalo, Olga Vega Matute, Marta Ferrer Puga, María José Goikoetxea Lapresa, Gabriel Gastaminza Lasarte, Antonia Thinnes, Hans F. Merk, Jens Malte Baron, Martin Leverkus, Galina Balakirski, Andrew Gibson, Monday Ogese, Zaid Al-Attar, Fiazia Yaseen, Xiaoli Meng, Rozalind Jenkins, John Farrel, Khetam Alhilali, Yanni Xue, Patricia Illing, Nicole Mifsud, Heidi Fettke, Jeffrey Lai, Rebecca Ho, Patrick Kwan, Anthony Purcell, Monday O. Ogese, Catherine Betts, Paul Thomson, Mohammad Alhaidari, Neill Berry, Paul M. O’Neill, Abdulaziz Alzahrani, Marie Eliane Azoury, Lucia Fili, Rami Bechara, Noémie Scornet, Cathy Nhim, Richard Weaver, Nancy Claude, Delphine Joseph, Bernard Maillere, Paola Parronchi, Marc Pallardy, Axel Patrice Villani, Aurore Rozières, Benoît Bensaïd, Mathilde Tardieu, Floriane Albert, Virginie Mutez, Tugba Baysal, Janet Maryanski, Jean-François Nicolas, Osami Kanagawa, Marc Vocanson, Shuen-Iu Hung, Caroline J. Harrison, Rosalind E. Jenkins, Neil S. French, Maria Isabel Montañez, Tahia D. Fernandez, Angela Martin-Serrano, Maria Jose Torres, Noemi Molina, Sally Wood, Munir Pirmohamed, María Isabel Montañez, Ángela Martín-Serrano, Ezequiel Pérez-Inestrosa, Dolores Pérez-Sala, Antonio E. Guzmán, Tai-Ming Ko, Yuan-Tsong Chen, Jer-Yuarn Wu, Francisco J. Sánchez-Gómez, Juan M. González-Morena, María J. Torres, Alejandra Monroy Arreola, Jesus Agustin Badillo Corona, Silvia Mendez Flores, Judith Dominguez Cherit, Noe Valentin Duran Figueroa, Jose Luis Castrejon Flores, James Perkins, Diana Pérez-Alzate, Gador Bogas, María J Torres, Luis Mario Tubella Marti, Fernando Pineda De La Losa, Francisca Arribas Poves, Jaime Tubella Lopez, Teodora Lopez Santiago

Publikováno v: Clinical and Translational Allergy

Table of contents Poster walk 11: miscellaneous drug hypersensitivity 2 (P92–P94, P96–P101) P92 16 years of experience with proton pump inhibitors (PPIs) Javier Dionicio Elera, Cosmin Boteanu, Maria Aranzazu Jimenez Blanco, Rosario Gonzalez-Mendi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b370b683975682734778f8449a5174