Výsledky vyhledávání - "Moncef Guenounou"

Akademický článek

Temporal patterns of the cerebral inflammatory response in the rat lithium–pilocarpine model of temporal lobe epilepsy

Autor: Brigitte Voutsinos-Porche, Estelle Koning, Hervé Kaplan, Arielle Ferrandon, Moncef Guenounou, Astrid Nehlig, Jacques Motte

Publikováno v: Neurobiology of Disease, Vol 17, Iss 3, Pp 385-402 (2004)

To better understand the role of inflammatory responses in temporal lobe epilepsy, we characterized Interleukin1-β (IL1-β), Nuclear Factor-κB (NF-κB), and Cyclooxygenase-2 (COX-2) expression together with neurodegeneration in the rat lithium–pi

Externí odkaz: https://doaj.org/article/4046a5c0bf1448198e3acc736dad3e33

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Akademický článek

Mecanismos efectores del interferón gamma contra la infección por Toxoplasma gondii

Autor: Jorge Enrique Gómez, Annie Bonhomme, Moncef Guenounou, Jean Michel Pinon

Publikováno v: Biomédica: revista del Instituto Nacional de Salud, Vol 19, Iss 4, Pp 311-20 (1999)

Toxoplasma gondiies un protozoario parásito de desarrollo intracelular. La enfermedad humana producida por T: gondii es una causa importante de morbilidad y mortalidad neonatal y en pacientes inmunodeprimidos. En esta reseña, se revisan los conocim

Externí odkaz: https://doaj.org/article/a477b296aeec4aefa39af36c885606c0

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Impairment of neutrophil reactivity to elastin peptides in COPD

Autor: Gaëtan Deslée, Frank Antonicelli, Aurélie Dupont, François Lebargy, Sandra Dury, Moncef Guenounou, Valérie Gafa, Richard Le Naour

Publikováno v: Thorax
Thorax, BMJ Publishing Group, 2013, 68 (5), pp.421-428

Rationale Neutrophils play an important role in the inflammatory process associated with chronic obstructive pulmonary disease (COPD). Lung-infiltrating neutrophils secrete elastinolytic proteases that participate in elastin breakdown and the formati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63489db07630ea4886376c09b5f9e9d4
https://doi.org/10.1136/thoraxjnl-2012-201833

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Induction and regulation of murine emphysema by elastin peptides

Autor: Christine Terryn, Moncef Guenounou, Caroline Fichel, Mehdi Sellami, Marie-Danièle Diebold, Nicole Bouland, Richard Le Naour, Aïda Meghraoui-Kheddar, Stéphanie Héry-Huynh

Publikováno v: American Journal of Physiology-Lung Cellular and Molecular Physiology
American Journal of Physiology-Lung Cellular and Molecular Physiology, American Physiological Society, 2016, 310 (1), pp.L8-L23. ⟨10.1152/ajplung.00068.2015⟩

Emphysema is the major component of chronic obstructive pulmonary disease (COPD). During emphysema, elastin breakdown in the lung tissue originates from the release of large amounts of elastase by inflammatory cells. Elevated levels of elastin-derive

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eafa643f7906aec65fd50735336a8ca0
https://hal.univ-reims.fr/hal-01770034

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Neutrophil Elastase Mediates Innate Host Protection against Pseudomonas aeruginosa

Autor: Azzaq Belaaouaj, Moncef Guenounou, Samuel Achilefu, Gaëtan Deslée, Tim O. Hirche, Robert E. W. Hancock, Rym Benabid, Sophie C. Gangloff, François Lebargy

Publikováno v: Scopus-Elsevier

According to the widely accepted view, neutrophil elastase (NE), a neutrophil-specific serine protease, is a major contributor to Pseudomonas aeruginosa infection-associated host tissue inflammation and damage, which in severe cases can lead to death

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a752b5f9f25dbb287fb69a747fa53751
https://doi.org/10.4049/jimmunol.181.7.4945

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MMP-2, MMP-9 and their inhibitors TIMP-2 and TIMP-1 production by human monocytes in vitro in the presence of different forms of hydroxyapatite particles

Autor: Alexia Grandjean-Laquerriere, Edouard Jallot, Patrice Laquerriere, Moncef Guenounou, Patrick Frayssinet, Salima Addadi-Rebbah, Dominique Laurent-Maquin

Publikováno v: Biomaterials
Biomaterials, 2004, 25 (13), pp.2515-24
Biomaterials, Elsevier, 2004, 25 (13), pp.2515-24

DOI : 10.1016/j.biomaterials.2003.09.034; After calcium-phosphates biomaterials based implantation like hydroxyapatite (HA) coating, particles are released in the periprosthetic tissues. Wear-debris induced fibrous membranes contain macrophage subset

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623b9d97f523191230eb2fb6ba8e0e8f
https://doi.org/10.1016/j.biomaterials.2003.09.034

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Toll-like receptors and immune response in allergic disease

Autor: Moncef Guenounou, Sophie C. Gangloff

Publikováno v: Clinical Reviews in Allergy & Immunology. 26:115-125

Allergic reactions are dominated by the preferential development of specific Th2 responses against innocuous antigens in atopic individuals. This can reflect alterations in innate immune mechanisms. Toll-like receptors (TLRs) have evolved as key mole

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d70d1f7d8063daf17c075050005278a
https://doi.org/10.1007/s12016-004-0006-0

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Influence of hydroxyapatite particle characteristics on the [K]/[Na] ratio: a human monocytes in vitro study

Autor: L. Kilian, Adrien Beorchia, Edouard Jallot, Alexia Grandjean-Laquerriere, Moncef Guenounou, Gérard Balossier, Patrice Laquerriere, Patrick Frayssinet

Publikováno v: Colloids and Surfaces B: Biointerfaces
Colloids and Surfaces B: Biointerfaces, Elsevier, 2004, 33, pp.39-44
Colloids and Surfaces B: Biointerfaces, 2004, 33, pp.39-44

Research in bone substitutes has shown that calcium phosphates, particularly hydroxyapatite are well adapted to use in prosthetics. Due to its characteristics that are close to those of bone, hydroxyapatite is used as a coating or bone defect filler.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c760b7146f01f8211fef11dac1013ae
https://doi.org/10.1016/j.colsurfb.2003.08.012

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Activation of the cellular mitogen-activated protein kinase pathways ERK, P38 and JNK duringToxoplasma gondiiinvasion

Autor: Isabelle Villena, Dominique Aubert, A. Valère, Roselyne Garnotel, Jean-Michel Pinon, Moncef Guenounou

Publikováno v: Parasite, Vol 10, Iss 1, Pp 59-64 (2003)

L'invasion d'une cellule hote est essentielle pour la pathogenicite de Toxoplasma gondii, parasite protozoaire mire-cellulaire obligatoire. Dans cette etude, nous evoluions la capacite des tachyzoites de T gondii a declencher la phosphorylation des d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53230ae7451b6123980b0a2d7e436440
https://doi.org/10.1051/parasite/2003101p59

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Inhibition of the Calcium Release-activated Calcium (CRAC) Current in Jurkat T Cells by the HIV-1 Envelope Protein gp160

Autor: Marc Paulais, Sophie C. Gangloff, Olivier Dellis, Moncef Guenounou, Jean-Pierre Rona, Danielle Tondelier, Franck Brouillard, François Bouteau, Jacques Teulon

Publikováno v: Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2002, 277 (8), pp.6044-6050. ⟨10.1074/jbc.M111831200⟩

International audience; The HIV-1 envelope glycoprotein gp120/160 has pleiotropic effects on T cell function. We investigated whether Ca(2+) signaling, a crucial step for T cell activation, was altered by prolonged exposure of Jurkat T cells to gp160

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b618ee2ab6f6fc2d8a3661806aa085
https://doi.org/10.1074/jbc.m111831200

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