Simultaneous sequencing of genetic and epigenetic bases in DNA.

Autor: Füllgrabe J; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Gosal WS; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Creed P; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Liu S; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Lumby CK; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Morley DJ; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Ost TWB; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Vilella AJ; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Yu S; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Bignell H; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Burns P; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Charlesworth T; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Fu B; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Fordham H; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Harding NJ; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Gandelman O; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Golder P; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Hodson C; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Li M; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Lila M; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Liu Y; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Mason J; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Mellad J; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Monahan JM; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Nentwich O; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Palmer A; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Steward M; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Taipale M; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Vandomme A; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., San-Bento RS; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Singhal A; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Vivian J; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Wójtowicz N; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Williams N; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Walker NJ; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Wong NCH; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Yalloway GN; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK., Holbrook JD; Cambridge Epigenetix Ltd, The Trinity Building, Chesterford Research Park, Cambridge, UK. Joanna.holbrook@cegx.co.uk., Balasubramanian S; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK. sb10031@cam.ac.uk.; Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK. sb10031@cam.ac.uk.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2023 Oct; Vol. 41 (10), pp. 1457-1464. Date of Electronic Publication: 2023 Feb 06.

IL10RA modulates crizotinib sensitivity in NPM1-ALK+ anaplastic large cell lymphoma.

Autor: Prokoph N; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Probst NA; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Lee LC; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Monahan JM; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, Cambridge, United Kingdom., Matthews JD; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Liang HC; Experimental and Laboratory Animal Pathology, Department of Pathology, Medical University of Vienna, Vienna, Austria., Bahnsen K; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Montes-Mojarro IA; Institute of Pathology and Neuropathology and Comprehensive Cancer Center Tübingen, University Hospital Tübingen, Eberhard-Karls-University, Tübingen, Germany., Karaca-Atabay E; Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA.; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Sharma GG; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy., Malik V; Department of Medicine, Columbia Center for Human Development, Columbia University Irving Medical Center, New York, NY., Larose H; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Forde SD; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Ducray SP; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Lobello C; Central European Institute of Technology, Masaryk University, Brno, Czech Republic., Wang Q; Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA., Luan SL; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Pospíšilová Š; Central European Institute of Technology, Masaryk University, Brno, Czech Republic.; Department of Internal Medicine-Hematology and Oncology, University Hospital Brno, Brno, Czech Republic., Gambacorti-Passerini C; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy., Burke GAA; Department of Pediatric Hematology, Oncology and Palliative Care, Addenbrooke's Hospital, Cambridge University Hospitals National Health Service (NHS) Foundation Trust, Cambridge, United Kingdom., Pervez S; Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan., Attarbaschi A; Department of Pediatric Hematology and Oncology, St. Anna Children's Hospital, Medical University of Vienna, Vienna, Austria.; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria., Janíková A; Department of Internal Medicine-Hematology and Oncology, University Hospital Brno, Brno, Czech Republic., Pacquement H; Department of Pediatric, Adolescent, and Young Adult Oncology, Institute Curie Medical Centre, Paris, France., Landman-Parker J; Department of Pediatric Oncology and Hematology, Sorbonne Université/Trousseau Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France., Lambilliotte A; Department of Pathology, (AP-HP), CHU Necker-Enfants Malades, Paris, France., Schleiermacher G; Oncology Center SIREDO (Care, Innovation, Research for Cancer in Children, Adolescents and Young Adults with Cancer), Institut Curie, Paris, France.; INSERM U830 Transfer Department, Laboratoire de Génétique et Biologie des Cancers, Institut Curie, Paris, France.; Equipe Integrated Cancer Research Site (SiRIC) Recherche Translationelle en Oncologie Pédiatrique (RTOP), Institut Curie, Paris, France., Klapper W; Department of Pathology, Hematopathology Section, Universitätsklinikum Schleswig-Holstein (UKSH) Campus Kiel, Kiel, Germany., Jauch R; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China., Woessmann W; Department of Pediatric Hematology and Oncology, University Hospital Hamburg-Eppendorf, Hamburg, Germany., Vassal G; Department of Clinical Research, Gustave Roussy Cancer Center, Villejuif, France., Kenner L; Department of Experimental Pathology and Laboratory Animal Pathology, Institute of Clinical Pathology, Medical University of Vienna, Vienna, Austria.; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, Austria.; Christian Doppler Laboratory for Applied Metabolomics, Medical University of Vienna, Vienna, Austria.; Center for Biomarker Research in Medicine (CBmed) Vienna, Core-Lab2, Medical University of Vienna, Vienna, Austria., Merkel O; Experimental and Laboratory Animal Pathology, Department of Pathology, Medical University of Vienna, Vienna, Austria., Mologni L; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy., Chiarle R; Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA.; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Brugières L; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Villejuif, France; and., Geoerger B; Department of Pediatric and Adolescent Oncology, Gustave Roussy Cancer Center, Villejuif, France; and.; INSERM U1015, Université Paris-Saclay, Villejuif, France., Barbieri I; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom., Turner SD; Division of Cellular and Molecular Pathology, Department of Pathology, University of Cambridge, Cambridge, United Kingdom.; Central European Institute of Technology, Masaryk University, Brno, Czech Republic.

Publikováno v: Blood [Blood] 2020 Oct 01; Vol. 136 (14), pp. 1657-1669.

A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis.

Autor: Morgan M; MRC Centre for Regenerative Medicine, School of Biological Sciences, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, UK.; European Molecular Biology Laboratory (EMBL), Via Ramarini 32, 00015, Monterotondo, Italy.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, UK., Kabayama Y; MRC Centre for Regenerative Medicine, School of Biological Sciences, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, UK.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, UK., Much C; MRC Centre for Regenerative Medicine, School of Biological Sciences, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, UK.; European Molecular Biology Laboratory (EMBL), Via Ramarini 32, 00015, Monterotondo, Italy., Ivanova I; MRC Centre for Regenerative Medicine, School of Biological Sciences, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, UK., Di Giacomo M; European Molecular Biology Laboratory (EMBL), Via Ramarini 32, 00015, Monterotondo, Italy., Auchynnikava T; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, UK., Monahan JM; European Bioinformatics Institute, Hinxton, Cambridge, CB10 1SD, UK., Vitsios DM; European Bioinformatics Institute, Hinxton, Cambridge, CB10 1SD, UK., Vasiliauskaitė L; MRC Centre for Regenerative Medicine, School of Biological Sciences, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, UK.; European Molecular Biology Laboratory (EMBL), Via Ramarini 32, 00015, Monterotondo, Italy., Comazzetto S; European Molecular Biology Laboratory (EMBL), Via Ramarini 32, 00015, Monterotondo, Italy., Rappsilber J; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, UK.; Institute of Biotechnology, Technische Universität Berlin, Berlin, 13355, Germany., Allshire RC; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, UK., Porse BT; Biotech Research and Innovation Center (BRIC), University of Copenhagen, Copenhagen, 2200, Denmark.; The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, 2200, Denmark.; Danish Stem Cell Centre (DanStem), Faculty of Health Sciences, University of Copenhagen, Copenhagen, 2200, Denmark., Enright AJ; European Bioinformatics Institute, Hinxton, Cambridge, CB10 1SD, UK., O'Carroll D; MRC Centre for Regenerative Medicine, School of Biological Sciences, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, UK. donal.ocarroll@ed.ac.uk.; Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh, EH9 3BF, UK. donal.ocarroll@ed.ac.uk.

Publikováno v: Cell research [Cell Res] 2019 Mar; Vol. 29 (3), pp. 221-232. Date of Electronic Publication: 2019 Jan 07.