Výsledky vyhledávání - "Mona S. Legator"

Preimplantation diagnosis of the aneuploidies most commonly found in spontaneous abortions and live births: XY, 13, 14, 15, 16, 18, 21, 22

Autor: Mona S. Legator, Larry Morrison, Muhterem Bahçe, Santiago Munné, Jacques Cohert, Luca Gianaroli, Jingly Fung, Cristina Magli

Publikováno v: Prenatal Diagnosis. 18:1459-1466

The present preimplantation diagnosis test is able to screen for the most common aneuploidies from single blastomeres in about five hours with a 15 per cent misdiagnosis. This means that the risk of spontaneous abortion and trisomic offspring for wom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a395c34fbcf6f401181b13fba752795f
https://doi.org/10.1002/(sici)1097-0223(199812)18:13<1459::aid-pd514>3.0.co

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Two-color ratio-coding of chromosome targets in fluorescence in situ hybridization: Quantitative analysis and reproducibility

Autor: Mona S. Legator, Larry E. Morrison

Publikováno v: Cytometry. 27:314-326

Ratio coding in fluorescence in situ hybridizations has the potential to identify more DNA and RNA targets simultaneously using fewer fluorescent labels than other multi-color techniques. Ratio coding uses hybridization probes containing different pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9398ea05adff45591e321d96fecb1c14
https://doi.org/10.1002/(sici)1097-0320(19970401)27:4<314::aid-cyto2>3.0.co

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Fluorescence in situ hybridization (FISH) as an ancillary diagnostic tool in the diagnosis of melanoma

Autor: Philip E. LeBoit, John Schulz, Beth Blondin, Susan Jewell, Scott R. Dalton, Susan L. Boone, Susan Charzan, Boris C. Bastian, Nicholas A. Kolaitis, Terakeith Lertsbarapa, Larry E. Morrison, Mona S. Legator, Paul Matushek, Pedram Gerami, Joan Guitart, Teresa Ruffalo, Kristine Jacobson

Publikováno v: The American journal of surgical pathology. 33(8)

Although the clinical and pathologic diagnosis of some melanomas is clear-cut, there are many histopathologic simulators of melanoma that pose problems. Over-diagnosis of melanoma can lead to inappropriate therapy and psychologic burdens, whereas und

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be894d6dadbd449634009e7c123fc79a
https://pubmed.ncbi.nlm.nih.gov/19561450

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The development of a fluorescence in situ hybridization assay for the detection of dysplasia and adenocarcinoma in Barrett's esophagus

Autor: Shannon M. Brankley, Aaron R. Harwood, Mona S. Legator, Lori S. Lutzke, Kevin C. Halling, Larry E. Morrison, Benjamin R. Kipp, Dylan V. Miller, Kenneth K. Wang

Publikováno v: The Journal of molecular diagnostics : JMD. 8(2)

The goal of this study was to identify a set of fluorescence in situ hybridization probes for the detection of dysplasia and adenocarcinoma in patients with Barrett's esophagus. We examined 170 brushing specimens from 138 patients with Barrett's esop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ec39b9b6be026c22606f3b62e1af64
https://pubmed.ncbi.nlm.nih.gov/16645214

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Gene copy mapping of the ERBB2/TOP2A region in breast cancer

Autor: Steve A. Seelig, John H. Proffitt, Kris Jacobson, Kimberly A. Wilber, Beth Blondin, Susan C. Van Stedum, John S. Coon, Larry E. Morrison, Benita T. Henderson, Mona S. Legator, Anna O'Hare

Publikováno v: Genes, chromosomescancer. 40(1)

ERBB2 is one of the most important oncogenes in breast cancer, and its disordered expression is commonly associated with gene amplification. Amplification of at least one gene near ERBB2, topoisomerase IIalpha (TOP2A), has been shown to be clinically

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd8691d3f1a7e5f33ac8fc417b6e2107
https://pubmed.ncbi.nlm.nih.gov/15034864

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Chromosomal gains and genomic loss of p53 and p16 genes in Barrett's esophagus detected by fluorescence in situ hybridization of cytology specimens

Autor: Marek Skacel, Gary W. Falk, Jennifer Brainard, Graham Casey, Raymond R. Tubbs, Mona S Legator, Jason T. Connor, John R. Goldblum, Thomas W. Rice, Mona Fahmy, Terry Gramlich

Publikováno v: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 17(5)

Endoscopic brush cytology is a promising surveillance technique for Barrett's esophagus. Ancillary markers are sought to increase the sensitivity of cytology and allow identification of patients at increased risk for disease progression. To determine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::070512b034cf1c695454f39a9ca96a9e
https://pubmed.ncbi.nlm.nih.gov/15017433

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Detection of chromosomal instability in paired breast surgery and ductal lavage specimens by interphase fluorescence in situ hybridization

Autor: Bonnie L, King, Steven C, Tsai, Michele E, Gryga, Thomas G, D'Aquila, Steven A, Seelig, Larry E, Morrison, Kris K B, Jacobson, Mona S, Legator, David C, Ward, David L, Rimm, Rogsbert F, Phillips

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 9(4)

Ductal lavage is a new modality for collecting exfoliated breast cells with the goal of detecting early neoplasia. The purpose of our study was to evaluate the correlation between cancer-associated abnormalities in breast lesions and exfoliated breas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::26ec37c140fc5eec3ad89c0b9d98a19b
https://pubmed.ncbi.nlm.nih.gov/12684427

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