A phase 1b study of unesbulin (PTC596) plus dacarbazine for the treatment of patients with locally recurrent, unresectable, or metastatic relapsed/refractory leiomyosarcoma

Autor: Brian Andrew Van Tine, Matthew Ingham, Steven Attia, Christian Frederick Meyer, John Baird, Dhiren D'Silva, Kylie O'Keefe, Pius Maliakal, Mona M. Wahba, Marla Weetall, Gary K. Schwartz

Publikováno v: Journal of Clinical Oncology. 40:11507-11507

11507 Background: Leiomyosarcoma (LMS) is one of the most common subtypes of soft tissue sarcoma and is associated with high risk of relapse and a poor prognosis for advanced disease. In preclinical LMS models, unesbulin, a microtubule polymerization

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f523fd5e6e9b50f0e3ee57a69a79d4e4
https://doi.org/10.1200/jco.2022.40.16_suppl.11507

Current management of chronic kidney disease in type-2 diabetes-A tiered approach: An overview of the joint Association of British Clinical Diabetologists and UK Kidney association (ABCD-UKKA) guidelines.

Autor: Dasgupta I; Heartlands Hospital, Birmingham and Warwick Medical School, University of Warwick, Coventry, UK., Zac-Varghese S; East and North Herts NHS Trust, Hertfordshire, UK., Chaudhry K; Guy's and St Thomas' Hospital, London, UK., McCafferty K; Barts Health NHS Trust, London, UK., Winocour P; East and North Herts NHS Trust, Hertfordshire, UK., Chowdhury TA; Royal London Hospital, London, UK., Bellary S; Aston University, Birmingham, UK., Goldet G; Imperial College Healthcare NHS Trust, London, UK., Wahba M; Epsom & St Helier University NHS Trust, London, UK., De P; City Hospital, Birmingham, UK., Frankel AH; Imperial College Healthcare NHS Trust, London, UK., Montero RM; St George's Hospital, London, UK., Lioudaki E; King's College Hospital, London, UK., Banerjee D; St George's University Hospitals NHS Foundation Trust, London, UK., Mallik R; University College London NHS Trust, London, UK., Sharif A; University Hospitals Birmingham, Birmingham, UK., Kanumilli N; Northenden Group Practice, Manchester, UK., Milne N; Greater Manchester Diabetes Clinical Network, Manchester, UK., Patel DC; Royal Free London NHS Foundation Trust, London, UK., Dhatariya K; Norfolk and Norwich University Hospitals NHS Foundation Trust and Norwich Medical School, University of East Anglia, Norwich, UK., Bain SC; Swansea University, Swansea, UK., Karalliedde J; Guy's and St Thomas' Hospital London and King's College London, London, UK.

Publikováno v: Diabetic medicine : a journal of the British Diabetic Association [Diabet Med] 2024 Oct 17, pp. e15450. Date of Electronic Publication: 2024 Oct 17.

Management of adults with diabetes on dialysis: Summary of recommendations of the Joint British Diabetes Societies guidelines 2022.

Autor: Frankel AH; Imperial College Healthcare NHS Trust, London, UK., Wahba M; Epsom and St Helier University Hospitals NHS Trust, Carshalton, UK., Ashworth V; School of Health Sciences, Institute of Clinical Sciences, University of Liverpool, Liverpool, UK., Bedi R; Imperial College Healthcare NHS Trust, London, UK., Berrington R; University Hospitals of Leicester NHS Trust, Leicester, UK., Buckley M; Kidney Care, Alton, UK., Chandrasekharan L; Mid and South Essex NHS Foundation Trust, Essex, UK., Doyle F; Epsom and St Helier University Hospitals NHS Trust, Carshalton, UK., Duval D; Kidney Care, Alton, UK., Game F; University Hospitals of Derby and Burton NHS Foundation, Derby, UK.; University of Nottingham, Nottingham, UK., Hamilton S; Manchester University NHS Foundation Trust, Manchester, UK., Hussain S; Guy's and St Thomas' NHS Trust, London, UK., James J; Leicester Diabetes Centre, Leicester, UK., Jebb H; Imperial College Healthcare NHS Trust, London, UK., Karalliedde J; Guy's and St Thomas' NHS Trust, London, UK., Kong MF; University Hospitals of Leicester NHS Trust, Leicester, UK., Kuverji A; University Hospitals of Leicester NHS Trust, Leicester, UK., Lambie M; Keele University, Keele, UK., Main C; University Hospital of Wales, Cardiff, UK., Price S; University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK., Wijewickrama P; University College London Hospitals NHS Trust, London, UK., Williams J; Royal Devon and Exeter NHS Trust, Exeter, UK., Dhatariya K; Norfolk and Norwich University Hospitals NHS Foundation Trust, Norwich, UK., Chowdhury TA; Department of Diabetes and Metabolism, The Royal London Hospital, London, UK.

Publikováno v: Diabetic medicine : a journal of the British Diabetic Association [Diabet Med] 2023 Apr; Vol. 40 (4), pp. e15027. Date of Electronic Publication: 2022 Dec 23.

Clinical practice guidelines for management of hyperglycaemia in adults with diabetic kidney disease.

Autor: Karalliedde J; Consultant Diabetologist, Guy's and St Thomas' Hospital London and King's College London, London, UK., Winocour P; Consultant Diabetologist, East and North Herts Institute of Diabetes and Endocrinology, East and North Herts NHS Trust, Welwyn Garden City, UK., Chowdhury TA; Consultant Diabetologist, Royal London Hospital, London, UK., De P; Consultant Diabetologist, City Hospital, Birmingham, UK., Frankel AH; Consultant Nephrologist, Imperial College Healthcare NHS Trust, London, UK., Montero RM; Consultant Nephrologist, Royal Berkshire NHS Foundation Trust, Reading, UK., Pokrajac A; Consultant Diabetologist, West Hertfordshire Hospitals, Watford, UK., Banerjee D; Consultant Nephrologist, St George's Hospital, London, UK., Dasgupta I; Consultant Nephrologist, Heartlands Hospital, Birmingham, UK., Fogarty D; Consultant Nephrologist, Belfast Health and Social Care Trust, Belfast, UK., Sharif A; Consultant Nephrologist, University Hospitals Birmingham, Birmingham, UK., Wahba M; Consultant Nephrologist, St Helier Hospital, Carshalton, UK., Mark PB; Professor of Nephrology, Institute of Cardiovascular and Medical Sciences University of Glasgow, Glasgow, UK., Zac-Varghese S; Consultant Diabetologist, East and North Herts NHS Trust, Welwyn Garden City, UK., Patel DC; Consultant Endocrinologist, Royal Free London NHS Foundation Trust, London, UK.; Honorary Associate Professor, UCL, London, UK., Bain SC; Professor of Medicine (Diabetes), Swansea University, Swansea, UK.

Publikováno v: Diabetic medicine : a journal of the British Diabetic Association [Diabet Med] 2022 Apr; Vol. 39 (4), pp. e14769. Date of Electronic Publication: 2022 Jan 26.

Fludrocortisone Is an Effective Treatment for Hyperkalaemic Metabolic Acidosis in Kidney Transplant Recipients on Tacrolimus: A Case Series.

Autor: Gama RM; Renal Unit, St. Helier Hospital, Epsom and St Helier University Hospitals NHS Trust, Carshalton, United Kingdom., Makanjuola D; Renal Unit, St. Helier Hospital, Epsom and St Helier University Hospitals NHS Trust, Carshalton, United Kingdom., Wahba M; Renal Unit, St. Helier Hospital, Epsom and St Helier University Hospitals NHS Trust, Carshalton, United Kingdom., Quan V; Renal Unit, St. Helier Hospital, Epsom and St Helier University Hospitals NHS Trust, Carshalton, United Kingdom., Phanish M; Renal Unit, St. Helier Hospital, Epsom and St Helier University Hospitals NHS Trust, Carshalton, United Kingdom.

Publikováno v: Nephron [Nephron] 2022; Vol. 146 (2), pp. 190-196. Date of Electronic Publication: 2021 Nov 16.