Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Mona M. Kamel"'
Publikováno v:
Molecules, Vol 17, Iss 6, Pp 7217-7231 (2012)
A series of new thiophene derivatives has been synthesized using the Gewald protocol. The acetylcholinesterase inhibition activity was assayed according to Ellman’s method using donepezil as reference. Some of the compounds were found to be more po
Externí odkaz:
https://doaj.org/article/7b9960c6e5a9465b8ebabe4e6b1746ff
Publikováno v:
Molecules, Vol 17, Iss 5, Pp 4811-4823 (2012)
New series of indole derivatives analogous to donepezil, a well known anti-Alzheimer and acetylcholinesterase inhibitor drug, was synthesized. A full chemical characterization of the new compounds is provided. Biological evaluation of the new compoun
Externí odkaz:
https://doaj.org/article/1dcfc4bf73854fb8ad02388f5a88ed00
Publikováno v:
Drug Development Research. 83:1394-1407
A series of tetrahydrobenzothienopyrimidines and tetrahydrobenzothienotriazines incorporating a pharmacophore from donepezil molecule were designed and synthesized. The 12 newly synthesized compounds were screened for their inhibition activity agains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f105c4197d928ef66f7456e53d1a4103
https://doi.org/10.1002/ddr.21968
https://doi.org/10.1002/ddr.21968
Autor:
Kholoud I. Eissa, Mona M. Kamel, Lamia W. Mohamed, Ahmed S. Doghish, Radwan Alnajjar, Ahmed A. Al‐Karmalawy, Asmaa E. Kassab
Publikováno v:
Drug Development Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ab9dd81b56c9cfabdf89f2c90e581eb
https://doi.org/10.1002/ddr.22064
https://doi.org/10.1002/ddr.22064
Publikováno v:
Pediatric Sciences Journal. 1:11-14
Background: The various neurological disorders pose a significant proportion of morbidity and mortality among children. They pose significant social and economic challenges as well. Aim of work: To identify the spectrum of neurological disorders amon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::634f57b25f4e0edd4015fdeab1640a1b
https://doi.org/10.21608/cupsj.2020.48820.1008
https://doi.org/10.21608/cupsj.2020.48820.1008
Publikováno v:
Chemistry of Heterocyclic Compounds. 56:499-502
The present minireview summarizes the data published during the last decade (2012–2019) on the synthesis of nortopsentin analogs and the effect of the structural modifications on the biological activity of the synthesized analogs as antitumor, anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2abb10bf212d3dcff20f0c9d4702327
https://doi.org/10.1007/s10593-020-02687-4
https://doi.org/10.1007/s10593-020-02687-4
Publikováno v:
Medicinal Chemistry. 15:873-882
Background: Marine sponges and tunicates have been a wealthy source of cytotoxic compounds such as indole alkaloids. Most of the indole alkaloids show in vitro cytotoxic and antineoplastic activities against a wide range of cancer cell lines. Objecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e083399d93d1efb92d1e9d240ac3788
https://doi.org/10.2174/1573406415666190408125514
https://doi.org/10.2174/1573406415666190408125514
Publikováno v:
Archiv der Pharmazie. 356:2200398
Alzheimer's disease (AD) is one of the most prevalent geriatric diseases and a significant cause of high mortality. This crippling disorder is becoming more prevalent at an unprecedented rate, which has led to an increase in the financial cost of car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73dff583fd9e1710088bf68df5c430f4
https://doi.org/10.1002/ardp.202200398
https://doi.org/10.1002/ardp.202200398
Publikováno v:
Bioorganic chemistry. 113
Newly designed levofloxacin analogues were synthesized to act as topoisomerase II beta inhibitors (Topo2β). Their cytotoxic activity was screened against breast, liver, and leukemia cancer cell lines. The best activity against liver cancer cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::731dd4d1338df6d1405eed39ae481354
https://pubmed.ncbi.nlm.nih.gov/34091290
https://pubmed.ncbi.nlm.nih.gov/34091290
Publikováno v:
Fibers and Polymers. 19:2103-2111
The growing concern for the personal health and hygiene has created the necessity of acquiring wool fabric antibacterial activity. Silicon dioxide nanoparticles (SiO2 NPs) have appropriate features to enhance the functional properties of wool fabrics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9b2bdac6dcab7e94a8055f677462592
https://doi.org/10.1007/s12221-018-1056-x
https://doi.org/10.1007/s12221-018-1056-x