Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mona M. Abdel-Atty"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1290-1311 (2021)
A series of thieno[2,3-d]pyrimidine-based hydroxamic acid hybrids was designed and synthesised as multitarget anti-cancer agents, through incorporating the pharmacophore of EGFR, VEGFR2 into the inhibitory functionality of HDAC6. Three compounds (12c
Externí odkaz:
https://doaj.org/article/eeb7eae82d0b459aa242f5b53f80ad11
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1290-1311 (2021)
A series of thieno[2,3-d]pyrimidine-based hydroxamic acid hybrids was designed and synthesised as multitarget anti-cancer agents, through incorporating the pharmacophore of EGFR, VEGFR2 into the inhibitory functionality of HDAC6. Three compounds (12c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98940e5c0c70f0c5ba2d7783d063577
https://doaj.org/article/eeb7eae82d0b459aa242f5b53f80ad11
https://doaj.org/article/eeb7eae82d0b459aa242f5b53f80ad11
Autor:
Nahla A. Farag, Mona M. Abdel-Atty, Shaymaa E. Kassab, Khaled A.M. Abouzid, Rabah A. T. Serya
Publikováno v:
Bioorganic Chemistry. 57:65-82
In this study, five series of (E)-6-(4-substituted phenyl)-4-oxohex-5-enoic acids IIb-f (E), (E)-3-(4-(substituted)-phenyl)acrylic acids IIIa-g (E), 4-(4-(substituted)phenylamino)-4-oxobutanoic acids VIa,b,e, 5-(4-(substituted)phenylamino)-5-oxopenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8145ad10057501feb3d5287386599b6d
https://doi.org/10.1016/j.bioorg.2014.08.006
https://doi.org/10.1016/j.bioorg.2014.08.006