Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mona Khalaj"'
Autor:
Zaniar Ghazizadeh, Jiajun Zhu, Faranak Fattahi, Alice Tang, Xiaolu Sun, Sadaf Amin, Su-Yi Tsai, Mona Khalaj, Ting Zhou, Ryan M. Samuel, Tuo Zhang, Francis A. Ortega, Miriam Gordillo, Dorota Moroziewicz, Daniel Paull, Scott A. Noggle, Jenny Zhaoying Xiang, Lorenz Studer, David J. Christini, Geoffrey S. Pitt, Todd Evans, Shuibing Chen
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104153- (2022)
Summary: The sinoatrial node (SAN) is the primary pacemaker of the heart. The human SAN is poorly understood due to limited primary tissue access and limitations in robust in vitro derivation methods. We developed a dual SHOX2:GFP; MYH6:mCherry knock
Externí odkaz:
https://doaj.org/article/fef061437c7f48f58546ebc077cf20d3
Autor:
Hassan Rassouli, Mona Khalaj, Seyedeh-Nafiseh Hassani, Shiva Nemati, Ghasem Hosseini Salekdeh, Hossein Baharvand
Publikováno v:
Cell Journal, Vol 21, Iss 3, Pp 290-299 (2019)
Objective: Human embryonic stem cells (hESCs) have the potential to give rise to all types of cells in the human body when appropriately induced to differentiate. Stem cells can differentiate spontaneously into the three-germ layer derivatives by e
Externí odkaz:
https://doaj.org/article/4fef92b53251431fb95a78d30651fdaa
Autor:
Sadaf Amin, Brandoch Cook, Ting Zhou, Zaniar Ghazizadeh, Raphael Lis, Tuo Zhang, Mona Khalaj, Miguel Crespo, Manuradhi Perera, Jenny Zhaoying Xiang, Zengrong Zhu, Mark Tomishima, Chengyang Liu, Ali Naji, Todd Evans, Danwei Huangfu, Shuibing Chen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
GLIS3 mutations are associated with type 1, type 2, and neonatal diabetes. Here, the authors generate mono-hormonal glucose-responding pancreatic β-like cells in vitro and through a screen identify a drug that rescues pancreatic β-like cell death i
Externí odkaz:
https://doaj.org/article/c14e49f0fd174b1ebce0f8854fb56b94
Autor:
Alec W. Stranahan, Iryna Berezniuk, Sohini Chakraborty, Faye Feller, Mona Khalaj, Christopher Y. Park
Publikováno v:
Leukemia. 36(6)
Acute myeloid leukemia (AML) is characterized by poor clinical outcomes due to high rates of relapse following standard-of-care induction chemotherapy. While many pathogenic drivers have been described in AML, our understanding of the molecular mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361cacd40c6ae7f9f53ad4987c4d22b6
https://pubmed.ncbi.nlm.nih.gov/35461365
https://pubmed.ncbi.nlm.nih.gov/35461365
Autor:
Zaniar, Ghazizadeh, Jiajun, Zhu, Faranak, Fattahi, Alice, Tang, Xiaolu, Sun, Sadaf, Amin, Su-Yi, Tsai, Mona, Khalaj, Ting, Zhou, Ryan M, Samuel, Tuo, Zhang, Francis A, Ortega, Miriam, Gordillo, Dorota, Moroziewicz, Daniel, Paull, Scott A, Noggle, Jenny Zhaoying, Xiang, Lorenz, Studer, David J, Christini, Geoffrey S, Pitt, Todd, Evans, Shuibing, Chen
Publikováno v:
iScience. 25(4)
The sinoatrial node (SAN) is the primary pacemaker of the heart. The human SAN is poorly understood due to limited primary tissue access and limitations in robust
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d519a640ec8271ca23bd68d2f96d3e1b
https://pubmed.ncbi.nlm.nih.gov/35434558
https://pubmed.ncbi.nlm.nih.gov/35434558
Autor:
Raphael Lis, Ting Zhou, Brandoch D. Cook, Jenny Xiang, Todd Evans, Shuibing Chen, Mark J. Tomishima, Mona Khalaj, Zaniar Ghazizadeh, Zengrong Zhu, Ali Naji, Tuo Zhang, Sadaf Amin, Miguel Crespo, Manuradhi Perera, Chengyang Liu, Danwei Huangfu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications
Nature Communications
GLIS3 mutations are associated with type 1, type 2, and neonatal diabetes, reflecting a key function for this gene in pancreatic β-cell biology. Previous attempts to recapitulate disease-relevant phenotypes in GLIS3−/− β-like cells have been un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29a5bbc788c62955b41dff30f418abb
https://doaj.org/article/c14e49f0fd174b1ebce0f8854fb56b94
https://doaj.org/article/c14e49f0fd174b1ebce0f8854fb56b94
Publikováno v:
Translational Cancer Research. 5:S328-S331
Malignant blasts in acute myeloid leukemia (AML) are organized in a hierarchal manner resembling normal hematopoiesis, with leukemic stem cells (LSCs) at the apex, giving rise to more differentiated progeny with reduced capacity to self-renew (1). Fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::391c151759afdde787de8ac131beafd3
https://doi.org/10.21037/tcr.2016.07.15
https://doi.org/10.21037/tcr.2016.07.15
Autor:
Hassan Rassouli, Mona Khalaj, Seyedeh-Nafiseh Hassani, Shiva Nemati, Ghasem Hosseini Salekdeh, Hossein Baharvand
Publikováno v:
Cell Journal (Yakhteh)
Cell Journal, Vol 21, Iss 3, Pp 290-299 (2019)
Cell Journal, Vol 21, Iss 3, Pp 290-299 (2019)
Objective: Human embryonic stem cells (hESCs) have the potential to give rise to all types of cells in the human body when appropriately induced to differentiate. Stem cells can differentiate spontaneously into the three-germ layer derivatives by emb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::af74c6b278518a804fca90e2295bf7f3
https://pubmed.ncbi.nlm.nih.gov/31210435
https://pubmed.ncbi.nlm.nih.gov/31210435
Autor:
Mitera Hakim Shooshtari, Elham Shirazi, Mohammad Reza Mohammadi, Amene Saghazadeh, Mona Khalaj, Mohammadreza Shalbafan, Kaveh Alavi, Maryamalsadat Hosseini, Fatemeh Yousefi Laksari, Shahin Akhondzadeh
Publikováno v:
Journal of psychiatric research. 103
Inflammation as well as glutamate excitotoxicity have been proposed to participate in the propagation of autism. Palmitoylethanolamide (PEA) is an endocannabinoid proven to prevent glutamatergic toxicity and inhibit inflammatory responses simultaneou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957ffd3fb84372f223c54008a81c6328
https://pubmed.ncbi.nlm.nih.gov/29807317
https://pubmed.ncbi.nlm.nih.gov/29807317
Autor:
Christopher Y. Park, Mona Khalaj
Publikováno v:
Nature cell biology. 19(7)
The mechanism of action of oncogenes in acute myeloid leukaemia is poorly understood. A study now shows that the fusion oncoprotein AML1-ETO regulates leukaemogenesis by increasing the expression of small nucleolar RNAs through post-transcriptional m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75cac8b52c4d164151093e7d093c49e9
https://pubmed.ncbi.nlm.nih.gov/28659642
https://pubmed.ncbi.nlm.nih.gov/28659642