Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mona H. Badr"'
Autor:
Mona H. Badr, Heba A. Abd El Razik
Publikováno v:
Medicinal Chemistry Research. 27:442-457
Some novel polysubstituted pyrazoles, bipyrazoles and pyranopyrazoles, supported with various chemotherapeutically-active pharmacophores, were synthesized and biologically evaluated for their cytotoxic potential. Fifteen compounds (7–9, 12, 16, 17,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2abc4f011f9d8a9a8abc0c85802d8d70
https://doi.org/10.1007/s00044-017-2071-y
https://doi.org/10.1007/s00044-017-2071-y
Publikováno v:
CHEMICAL & PHARMACEUTICAL BULLETIN. 65:442-454
Two series of novel alkoxylated 2-oxo(imino)-3-pyridinecarbonitriles (structurally-relevant to some reported anticancer pyridines with phosphodiesterase 3A (PDE3A) inhibitory activity) were synthesized and evaluated for their in vitro differential tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71a25a88d953c27c07b482ff64373fb5
https://doi.org/10.1248/cpb.c16-00761
https://doi.org/10.1248/cpb.c16-00761
Publikováno v:
Archiv der Pharmazie. 348:824-834
A series of novel 1,4,6-trisubstituted-2-oxo-1,2-dihydropyridine-3-carbonitriles supported with some functionalities reported to contribute to significant chemotherapeutic potential were synthesized and evaluated for their antimicrobial and/or cytoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::303afb75ed6b7ea0d3fb9113555cb644
https://doi.org/10.1002/ardp.201500175
https://doi.org/10.1002/ardp.201500175
Autor:
S. M. Rida, Fawzia A. Ashour, Mostafa M.M. El-Miligy, Ehab M El-Bassiony, Mona H. Badr, Ashraf M Omar, Maha A El-Demellawy
Publikováno v:
Future Science OA
Aim: Simultaneous inhibition of hepatitis C virus (HCV) and hepatocellular carcinoma (HCC) may enhance anti-HCV effects and reduce resistance and side effects. Results/methodology: Novel hybrid derivatives were designed and synthesized to exhibit dua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::088f2f5eb278c091fb9c5392f4510fb0
https://pubmed.ncbi.nlm.nih.gov/29255624
https://pubmed.ncbi.nlm.nih.gov/29255624
Publikováno v:
European journal of medicinal chemistry. 139
Synthesis of twenty nine new 1,2,4-triazoles and some derived thiazolothiadiazoles (structurally-relevant to some reported triazoles with anticancer and/or Cdc25A/B inhibitory activities) is described in this study. The obtained NCI's in vitro antitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dddf88d3074d6e0a2125b39f69b40c4
https://pubmed.ncbi.nlm.nih.gov/28803043
https://pubmed.ncbi.nlm.nih.gov/28803043
Publikováno v:
Archiv der Pharmazie. 350(5)
Two series of benzodioxole-pyrazole hybrids were synthesized and the IC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::37fe17d99008ac49ee3ee3a33e31df21
https://pubmed.ncbi.nlm.nih.gov/28418202
https://pubmed.ncbi.nlm.nih.gov/28418202
Publikováno v:
Medicinal Chemistry. 8:151-162
Most of cancer chemotherapeutics and chemopreventives exert their effects by triggering apoptotic cell death. In this study, novel benzimidazole and benzothiazole derivatives have been synthesized to investigate their effects on HepG2 liver cancer ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f70da9789d0706a8acdcf8998d86cd3a
https://doi.org/10.2174/157340612800493719
https://doi.org/10.2174/157340612800493719
Publikováno v:
Arzneimittelforschung. 62:63-74
Novel benzimidazoles, benzothiazoles and benzofurans incorporating pyrazole moiety have been synthesized and screened for their antiangogenic activities, by testing their ability to inhibit human umbilical vein endothelial cell (HUVEC) proliferation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b702b0c718283fcb859956b07518707
https://doi.org/10.1055/s-0031-1295483
https://doi.org/10.1055/s-0031-1295483
Autor:
Hayam M. A. Ashour, Heba A. Abd El Razik, Abeer E. Abdel Wahab, Mona H. Badr, Sherif A. F. Rostom
Publikováno v:
Archiv der Pharmazie. 344:572-587
The synthesis of a series of certain polymethoxy chalcones and some derived pyrazole, pyrimidine, and thiazolopyrimidine ring structures is reported. Eleven compounds 4, 6, 9, 11, 14-17, 22, 24, and 25 were selected by the National Cancer Institute (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2699d9a4841925f4270e39828456d122
https://doi.org/10.1002/ardp.201100077
https://doi.org/10.1002/ardp.201100077
Publikováno v:
Medicinal Chemistry Research. 21:1107-1119
In an effort to etablish new candidates with improved antineoplastic, anti-HIV-1 and antimicrobial activities, the synthesis of some new triazino and triazolo[4,3-e]purine derivatives is described: 6,8-dimethyl-1,4-dihydro-1,2,4-triazino[4,3-e]purine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9688ac3171ef3def3e9a9180360967ea
https://doi.org/10.1007/s00044-011-9612-6
https://doi.org/10.1007/s00044-011-9612-6