Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mona F. Said"'
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 701-717 (2022)
In continuation of our previous studies to optimise potent carbonic anhydrase inhibitors, two new series of isatin N-phenylacetamide based sulphonamides were synthesised and screened for their human (h) carbonic anhydrase (EC 4.2.1.1) inhibitory acti
Externí odkaz:
https://doaj.org/article/149f050552d64e99be4b9484a019b771
Autor:
Riham M. Bokhtia, Siva S. Panda, Adel S. Girgis, Nermin Samir, Mona F. Said, Anwar Abdelnaser, Soad Nasr, Mohamed S. Bekheit, Abdelhameed S. Dawood, Horrick Sharma, Margaret Wade, Swapnil K. Sharma, Amany M. Ghanim
Publikováno v:
Molecules, Vol 28, Iss 4, p 1945 (2023)
New sets of ibuprofen and indomethacin conjugates comprising triazolyl heterocycle were synthesized via click chemistry, adopting an optimized protocol through the molecular hybridization approach affording the targeted agents in good yields. The new
Externí odkaz:
https://doaj.org/article/4d007e785d3e42d58d821718c0621459
Autor:
M. Adel Youssef, Siva S. Panda, Dalia R. Aboshouk, Mona F. Said, Ahmed El Taweel, Mohamed GabAllah, Walid Fayad, Ahmed F. Soliman, Ahmed Mostafa, Nehmedo G. Fawzy, Adel S. Girgis
Publikováno v:
ChemistrySelect. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddc9a881243f3df22607c15bcb40ca66
https://doi.org/10.1002/slct.202201406
https://doi.org/10.1002/slct.202201406
Autor:
Israa A. Seliem, Siva S. Panda, Adel S. Girgis, Queen L. Tran, Mona F. Said, Mohamed S. Bekheit, Anwar Abdelnaser, Soad Nasr, Walid Fayad, Ahmed A. F. Soliman, Rajeev Sakhuja, Tarek S. Ibrahim, Zakaria K. M. Abdel‐Samii, Amany M. M. Al‐Mahmoudy
Publikováno v:
ChemMedChem. 17(13)
Three sets of isatin-based Schiff bases were synthesized utilizing the molecular hybridization approach. Some of the synthesized Schiff bases show significant to moderate antiproliferative properties against MCF7 (breast), HCT116 (colon), and PaCa2 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca27cb08058bf504b4b1f7d22bb8633
https://pubmed.ncbi.nlm.nih.gov/35511203
https://pubmed.ncbi.nlm.nih.gov/35511203
Autor:
Amany M. Ghanim, Adel S. Girgis, Benson M. Kariuki, Nermin Samir, Mona F. Said, Anwar Abdelnaser, Soad Nasr, Mohamed S. Bekheit, Mohamed F. Abdelhameed, Ahmad J. Almalki, Tarek S. Ibrahim, Siva S. Panda
Publikováno v:
Bioorganic chemistry. 119
A new set of ibuprofen-quinoline conjugates comprising quinolinyl heterocycle and ibuprofen moieties linked by an alkyl chain were synthesized in good yields utilizing an optimized reaction procedure in a molecular hybridization approach to overcome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d44b72bea63c046404753394d13995
https://pubmed.ncbi.nlm.nih.gov/34952242
https://pubmed.ncbi.nlm.nih.gov/34952242
Publikováno v:
European journal of medicinal chemistry. 224
Addressing the global need for the development of safe and potent NSAIDs, new series of oxadiazolo and thiadiazolo fused pyrmidinones were synthesized and initially tested for their analgesic activity. All tested compounds showed promising analgesic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fa4bf24cf3c943eb8e6bfdc5b4820d
https://pubmed.ncbi.nlm.nih.gov/34245948
https://pubmed.ncbi.nlm.nih.gov/34245948
Publikováno v:
Bioorganic Chemistry. 115:105253
Responding to the great demand of developing potent NSAIDs with an enhanced safety profile and reasonable selectivity, in the present study novel 4-fluorobenzamide derivatives were synthesized and screened for their anti-inflammatory and analgesic ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bad9a284f2555eeeaa12e2b89e1a0b0
https://doi.org/10.1016/j.bioorg.2021.105253
https://doi.org/10.1016/j.bioorg.2021.105253
Publikováno v:
Bioorganic Chemistry. 95:103514
Three series of 2-oxindole benzenesulfonamide conjugates with different linkers were prepared by the condensation reaction of isatin derivatives 1a-e with different benzenesulfonamides. They were screened for their ability to inhibit human (h) carbon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ffe844edfa6d546ba3d53feefd4b03
https://doi.org/10.1016/j.bioorg.2019.103514
https://doi.org/10.1016/j.bioorg.2019.103514
Publikováno v:
Future medicinal chemistry. 9(6)
Aim: The discovery of new generation of selective COX-2 inhibitors with potential analgesic and anti-inflammatory activity and minimal side effects is a major interest. Materials & methods: Novel imidazole and imidazo[1,5-a]quinazoline derivatives we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6af57e61e4ff53d92fa168e0f1db0b9a
https://pubmed.ncbi.nlm.nih.gov/28394629
https://pubmed.ncbi.nlm.nih.gov/28394629
Publikováno v:
European Journal of Medicinal Chemistry. 63:645-654
Some novel 1,3,4-trisubstituted pyrazoles were synthesized and screened for their anti-inflammatory and analgesic activities as well as their ulcerogenic liability. They showed anti-inflammatory and analgesic activities with better GIT tolerance than
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21937e8fc98b4c80af6f405790af837a
https://doi.org/10.1016/j.ejmech.2013.03.005
https://doi.org/10.1016/j.ejmech.2013.03.005