Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Mona Boules"'
Publikováno v:
Behavioral Sciences, Vol 4, Iss 1, Pp 42-52 (2014)
Tobacco usage typically precedes illicit drug use in adolescent and young adult populations. Several animal studies suggest nicotine increases the risk for subsequent cocaine abuse, and may be a negative prognostic factor for treatment of cocaine add
Externí odkaz:
https://doaj.org/article/9117764581534592911813e3e54c3322
Publikováno v:
Neurobiology of Disease, Vol 40, Iss 2, Pp 467-477 (2010)
Much evidence suggests that targeting the neurotensin (NT) system may provide a novel and promising treatment for schizophrenia. Our recent work shows that: NTS1 knockout (NTS1−/−) mice may provide a potential animal model for studying schizophre
Externí odkaz:
https://doaj.org/article/9324419dd23e42e1a72db4c0b7fd247d
Publikováno v:
The Open Pain Journal. 7:23-28
The analgesic efficacy of neurotensin agonists depends on their activation of two receptor subtypes, NTS1 and/or NTS2. In this study we determined the role of NTS2 in an animal model of persistent pain (intraplantar injection of formalin) with the us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87148b0139020391cbb3513938b62295
https://doi.org/10.2174/1876386301407010023
https://doi.org/10.2174/1876386301407010023
Publikováno v:
Behavioral Sciences
Behavioral Sciences, Vol 4, Iss 1, Pp 42-52 (2014)
Behavioral Sciences, Vol 4, Iss 1, Pp 42-52 (2014)
Tobacco usage typically precedes illicit drug use in adolescent and young adult populations. Several animal studies suggest nicotine increases the risk for subsequent cocaine abuse, and may be a negative prognostic factor for treatment of cocaine add
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a429c7fa9ab27cc359d7eb73d3ac4d79
http://europepmc.org/articles/PMC4219249
http://europepmc.org/articles/PMC4219249
Publikováno v:
Behavioural pharmacology. 27(2-3 Spec)
Neurotensin (NT) is a neuropeptide that acts as a neurotransmitter and neuromodulator in the central nervous system. Several studies suggest a therapeutic role for NT analogs in nicotine and other psychostimulant addictions. We studied the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26d7db6b51a3a48f03082e9628474aa
https://pubmed.ncbi.nlm.nih.gov/26901162
https://pubmed.ncbi.nlm.nih.gov/26901162
Publikováno v:
Behavioural Brain Research. 232:93-97
Neurotensin (NT) analogs, NT69L, NT72, and NT79, differentially bind the two major neurotensin receptors, NTS1 and NTS2, to elicit effects similar to those of endogenous NT, including analgesia. Previous data strongly suggest NTS2 as the main recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c670c7218db1d91263c0451f82240b3
https://doi.org/10.1016/j.bbr.2012.03.044
https://doi.org/10.1016/j.bbr.2012.03.044
Publikováno v:
Behavioural Brain Research. 224:344-349
NT69L is a neurotensin (NT)(8-13) analog that binds the two major NT receptors, NTS1 and NTS2, and elicits similar behavioral effects as endogenous NT. Tolerance develops rapidly to some, but not to all of NT69L's effects, and to date, little is know
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec8c354b0f4ad1ec3dc156a1bd2c699
https://doi.org/10.1016/j.bbr.2011.06.014
https://doi.org/10.1016/j.bbr.2011.06.014
Autor:
Amanda Shaw, Jessica Robinson, Alfredo Oliveros, Mona Boules, Paul A. Fredrickson, Katrina Williams, Elliott Richelson, Yanqi Liang
Publikováno v:
Neuropeptides. 45:9-16
NT69L is a neurotensin analog that blocks nicotine-induced locomotor activity and has sustained efficacy in a rat model of nicotine-induced sensitization when administered peripherally. Additionally, NT69L attenuates food-reinforcement in rats. The p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ae42f7d59702d1c32a8a74adbec4ec
https://doi.org/10.1016/j.npep.2010.09.003
https://doi.org/10.1016/j.npep.2010.09.003
Autor:
Katrina Williams, Elliott Richelson, Michael G. Heckman, Mona Boules, Maria del Pilar Corena-McLeod, Alfredo Oliveros
Publikováno v:
Journal of Experimental Biology. 213:4232-4239
SUMMARY Pre-pulse inhibition (PPI) of the acoustic startle reflex is deficient in patients with schizophrenia. This deficiency is mimicked in mice by the use of the psychotomimetic drugs d-amphetamine and dizolcipine. Antipsychotic drugs such as cloz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f75ab94e47cae92f273645d43d3552
https://doi.org/10.1242/jeb.046318
https://doi.org/10.1242/jeb.046318
Publikováno v:
Neurobiology of Disease, Vol 40, Iss 2, Pp 467-477 (2010)
Much evidence suggests that targeting the neurotensin (NT) system may provide a novel and promising treatment for schizophrenia. Our recent work shows that: NTS1 knockout (NTS1(-/-)) mice may provide a potential animal model for studying schizophreni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1175ca04b3bc594bceec975bc4b82d
http://www.sciencedirect.com/science/article/pii/S0969996110002354
http://www.sciencedirect.com/science/article/pii/S0969996110002354