Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Mona Batish"'
Autor:
Keisuke Katsushima, Kandarp Joshi, Menglang Yuan, Brigette Romero, Mona Batish, Stacie Stapleton, George Jallo, Elayaraja Kolanthai, Sudipta Seal, Olivier Saulnier, Michael D. Taylor, Robert J. Wechsler-Reya, Charles G. Eberhart, Ranjan J. Perera
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113938- (2024)
Summary: Recent studies suggest that long non-coding RNAs (lncRNAs) contribute to medulloblastoma (MB) formation and progression. We have identified an lncRNA, lnc-HLX-2-7, as a potential therapeutic target in group 3 (G3) MBs. lnc-HLX-2-7 RNA specif
Externí odkaz:
https://doaj.org/article/4f95873122404b64823c7c17eb939dbe
Autor:
Christos K. Kontos, Paraskevi Karousi, Pinelopi I. Artemaki, Ahmed Abdelgawad, Aspasia Dimitriadou, Nikolaos P. Machairas, Diamantis C. Sideris, Vasiliki Pappa, Andreas Scorilas, Mona Batish, Sotirios G. Papageorgiou
Publikováno v:
FEBS Open Bio, Vol 13, Iss 10, Pp 1953-1966 (2023)
Circular RNAs (circRNAs), a novel RNA type generated by back‐splicing, are key regulators of gene expression, with deregulated expression and established involvement in leukemia. The products of BCL2 and its homologs, including BAX and BCL2L12, are
Externí odkaz:
https://doaj.org/article/38ab993d7992459e85d7e6f8dcbdccb7
Publikováno v:
Cells, Vol 12, Iss 24, p 2813 (2023)
CircRNAs are a category of regulatory RNAs that have garnered significant attention in the field of regulatory RNA research due to their structural stability and tissue-specific expression. Their circular configuration, formed via back-splicing, resu
Externí odkaz:
https://doaj.org/article/5c0eb44b12d047ac86c82f07dfd97c76
Autor:
Roberta Piras, Emily Y. Ko, Connor Barrett, Marco De Simone, Xianzhi Lin, Marina T. Broz, Fernando H. G. Tessaro, Mireia Castillo-Martin, Carlos Cordon-Cardo, Helen S. Goodridge, Dolores Di Vizio, Mona Batish, Kate Lawrenson, Y. Grace Chen, Keith Syson Chan, Jlenia Guarnerio
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Circular RNAs can contribute to tumour progression. Here the authors show that two circular RNAs, circCsnk1g3 and circAnkib1 promote sarcoma growth by controlling the expression of interferon related genes and pro-inflammatory factors in sarcoma cell
Externí odkaz:
https://doaj.org/article/ce63810cc8a74cdea3778e236afde9f9
Autor:
Karyn G. Robinson, Adam G. Marsh, Stephanie K. Lee, Jonathan Hicks, Brigette Romero, Mona Batish, Erin L. Crowgey, M. Wade Shrader, Robert E. Akins
Publikováno v:
Journal of Personalized Medicine, Vol 12, Iss 12, p 1978 (2022)
Spastic type cerebral palsy (CP) is a complex neuromuscular disorder that involves altered skeletal muscle microanatomy and growth, but little is known about the mechanisms contributing to muscle pathophysiology and dysfunction. Traditional genomic a
Externí odkaz:
https://doaj.org/article/eedf236d31e1441589cf4dd70bbed0ed
Publikováno v:
Cancers, Vol 14, Iss 2, p 428 (2022)
Circular RNAs (circRNAs) are regulatory RNAs which have recently been shown to have clinical significance in several diseases, including, but not limited to, various cancers, neurological diseases and cardiovascular diseases. The function of such reg
Externí odkaz:
https://doaj.org/article/33d5b6d73def43e1b69f60f21a8957fe
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 11, p 1187 (2021)
Cerebral palsy is a set of common, severe, motor disabilities categorized by a static, nondegenerative encephalopathy arising in the developing brain and associated with deficits in movement, posture, and activity. Spastic CP, which is the most commo
Externí odkaz:
https://doaj.org/article/e3e420545f174d9a85707927d1c656d8
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 933 (2021)
Ewing’s sarcoma (ES) is a pediatric sarcoma caused by a chromosomal translocation. Unlike in most cancers, the genomes of ES patients are very stable. The translocation product of the EWS-FLI1 fusion is most often the predominant genetic driver of
Externí odkaz:
https://doaj.org/article/ad2d8ea82ba24056979c74051becb1c9
Publikováno v:
Cells, Vol 10, Iss 6, p 1300 (2021)
Ewing’s sarcoma (ES) is caused by a chromosomal translocation leading to the formation of the fused EWSFLI1 gene, which codes for an aberrant transcription factor EWSFLI1. The transcriptional targets of EWSFLI1 have been viewed as promising and nov
Externí odkaz:
https://doaj.org/article/fd78cd4bc41842078fbf0a488ebde7b2
Autor:
Siddha Kasar, Chingiz Underbayev, Moinuddin Hassan, Ilko Ilev, Heba Degheidy, Steven Bauer, Gerald Marti, Carol Lutz, Elizabeth Raveche, Mona Batish
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149331 (2016)
New Zealand Black (NZB) mice, a de novo model of CLL, share multiple characteristics with CLL patients, including decreased expression of miR-15a/16-1. We previously discovered a point mutation and deletion in the 3' flanking region of mir-16-1 of NZ
Externí odkaz:
https://doaj.org/article/240691af79bb467eb52b2f9e2561aaaa