Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mona Aljuhani"'
Publikováno v:
Stem Cell Research, Vol 74, Iss , Pp 103281- (2024)
NOTCH1 signaling is crucial for cardiovascular development. Numerous studies have identified heterozygous NOTCH1 loss of function and missense variants associated with a spectrum of congenital heart diseases (CHD). We generated induced pluripotent st
Externí odkaz:
https://doaj.org/article/8bcca3e42d90409fa76dbaa88ad6e715
Autor:
Hui Lin, Shi-Qiao Ye, Zhao-Hui Xu, Jacqueline S. Penaloza, Mona Aljuhani, Tatyana Vetter, Ming-Tao Zhao, Kim L. McBride
Publikováno v:
Stem Cell Research, Vol 65, Iss , Pp 102958- (2022)
Epstein-Barr virus (EBV) immortalized lymphoblastoid cell lines (LCLs) are widely used for banking. This bioresource could be leveraged for creating human iPSC lines to model diseases including CHD. We generated an LCL-derived iPSC line (NCHi001-A) f
Externí odkaz:
https://doaj.org/article/d150bff3d73f43239f33ed94ee5d9e8e
Autor:
Dipanwita Sengupta, Teresa Cassel, Kun-yu Teng, Mona Aljuhani, Vivek K. Chowdhary, Peng Hu, Xiaoli Zhang, Teresa W.-M. Fan, Kalpana Ghoshal
Publikováno v:
Molecular Metabolism, Vol 34, Iss , Pp 174-186 (2020)
Objective: It is well established that the liver-specific miR-122, a bona fide tumor suppressor, plays a critical role in lipid homeostasis. However, its role, if any, in amino acid metabolism has not been explored. Since glutamine (Gln) is a critica
Externí odkaz:
https://doaj.org/article/e94018977b7a47ee8dc02a6ee0c626c7
Autor:
Teresa W.-M. Fan, Xiaoli Zhang, Teresa Cassel, Kalpana Ghoshal, Kun-Yu Teng, Vivek Chowdhary, Peng Hu, Dipanwita Sengupta, Mona Aljuhani
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 34, Iss, Pp 174-186 (2020)
Molecular Metabolism, Vol 34, Iss, Pp 174-186 (2020)
Objective It is well established that the liver-specific miR-122, a bona fide tumor suppressor, plays a critical role in lipid homeostasis. However, its role, if any, in amino acid metabolism has not been explored. Since glutamine (Gln) is a critical
Autor:
Andrew W. Duncan, Kalpana Ghoshal, Frances Alencastro, Lianbo Yu, Ladan Navari, Juan M. Barajas, Kara N. Corps, Mona Aljuhani, Hui-Lung Sun, Chuan He, Allen C. Zhu, Selen A. Yilmaz, Cho-Hao Lin
Publikováno v:
Am J Pathol
N6-methyladenosine (m6A), the most abundant internal modification of mRNAs and is installed by METTL3 at the (G/A)(m6A)C motif, plays a critical role in gene expression regulation. METTL3 is essential for embryonic development, and its dysregulation
Publikováno v:
The FASEB Journal. 32