Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mon-Gy Chen"'
Autor:
Madan Jagasia, Mon-Gy Chen, R. Lizambri, Edmund K. Waller, Simon Durrant, Gwynn D. Long, Brian J. Bolwell, Jeff Szer, Ginna G. Laport, Tsiporah B. Shore, Rafat Abonour
Publikováno v:
Bone Marrow Transplantation. 47:1350-1355
This prospective, randomized, double-blind, placebo-controlled study evaluated the efficacy of palifermin to reduce the incidence of severe (grade 3-4) acute GVHD after myeloablation and allo-SCT. Adults who received allo-SCT for hematologic malignan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55667e5d9f7a68d01406cf167a17028b
https://doi.org/10.1038/bmt.2011.261
https://doi.org/10.1038/bmt.2011.261
Autor:
Mon-Gy Chen, Marc Alfonsi, Laura Cerezo, Paolo Foa, Michael Henke, Lara Emmerson, Richard Lizambri, Etienne Bardet, Michaela Salzwimmer, Jordi Giralt, Dietmar Berger
Publikováno v:
Journal of Clinical Oncology. 29:2815-2820
Purpose Radiochemotherapy of head and neck cancer causes severe mucositis in most patients. We investigated whether palifermin reduces this debilitating sequela. Methods We conducted a multicenter, double-blind, randomized, placebo-controlled trial i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f603a226b57bcc44dbe087d1c01831e3
https://doi.org/10.1200/jco.2010.32.4103
https://doi.org/10.1200/jco.2010.32.4103
Autor:
Sabine Reinisch, Györgyi Muraközy, Dietmar Berger, Quynh-Thu Le, Harold Kim, Michael Henke, Charles J. Schneider, May Mo, Krzysztof Składowski, Richard Lizambri, Yuhchyau Chen, Mon Gy Chen, Michael Hickey
Publikováno v:
Journal of Clinical Oncology. 29:2808-2814
Purpose Oral mucositis (OM) is a debilitating toxicity of chemoradiotherapy for head and neck cancer (HNC). This randomized, placebo-controlled, double-blind study evaluated the efficacy and safety of palifermin to reduce OM associated with definitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0959ae7433539affb2e34a32fef4e0d8
https://doi.org/10.1200/jco.2010.32.4095
https://doi.org/10.1200/jco.2010.32.4095
Autor:
Mon Gy Chen, David M. Brizel, Ruby F. Meredith, Kishan J. Pandya, David I. Rosenthal, Barbara A. Murphy, William M. Mendenhall, Herbert E. Brizel, Dietmar Berger, Stefan Glück
Publikováno v:
Journal of Clinical Oncology. 26:2489-2496
Purpose Acute mucositis is a dose-limiting toxicity of concurrent chemoradiotherapy regimens for locally advanced head and neck cancer. Palifermin (a recombinant human keratinocyte growth factor; ΔN23-KGF) stimulates the proliferation and differenti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c43f1bc596b63999fada4fc12ca54efb
https://doi.org/10.1200/jco.2007.13.7349
https://doi.org/10.1200/jco.2007.13.7349
Autor:
Ian D. Davis, Alessandra Cesano, Ehtesham Abdi, Mon Gy Chen, Lee S. Rosen, Frederick M. Schnell, Urte Gayko, John Gutheil, John Zalcberg, Stephen Clarke
Publikováno v:
Journal of Clinical Oncology. 24:5194-5200
Purpose To characterize the efficacy and safety of palifermin in reducing the incidence of oral mucositis (OM) and diarrhea when administered to patients with metastatic colorectal cancer (CRC) receiving fluorouracil/leucovorin (FU/LV) chemotherapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0446fa111ea88d4df40c8569d0b92ac2
https://doi.org/10.1200/jco.2005.04.1152
https://doi.org/10.1200/jco.2005.04.1152
Publikováno v:
Pharmaceutical Statistics. 5:273-281
The term 'futility' is used to refer to the inability of a clinical trial to achieve its objectives. In particular, stopping a clinical trial when the interim results suggest that it is unlikely to achieve statistical significance can save resources
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7311486501f7a6c0bf402e4606f89b26
https://doi.org/10.1002/pst.216
https://doi.org/10.1002/pst.216
Publikováno v:
American Journal of Hematology. 76:205-213
Immune thrombocytopenia purpura (ITP) is characterized by destruction of circulating platelets and the presence of antiplatelet antibodies. Many of the current immunomodulatory therapies act by reducing platelet destruction and usually do not have a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b91912f971f48cd1750c7bbe2e0470a
https://doi.org/10.1002/ajh.20104
https://doi.org/10.1002/ajh.20104
Autor:
Mon-Gy Chen
Publikováno v:
Encyclopedia of Biopharmaceutical Statistics ISBN: 1439822468
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22344a3dcf262b5fe359e7f15deb0b55
https://doi.org/10.3109/9781439822463.110
https://doi.org/10.3109/9781439822463.110
Autor:
Daniel J. Weisdorf, Teresa Gentile, Mon-Gy Chen, Thomas B. Shea, Ricardo Spielberger, Patrick J. Stiff, Bruce R. Blazar, Dieter Elhardt, Tarun Kewalramani, Saul Yanovich, William I. Bensinger, Eric C. Sung, C. Frederick LeMaistre, Stephen J. Noga, Christos Emmanouilides, John M. McCarty, Keith Hansen
BACKGROUND Oral mucositis is a complication of intensive chemotherapy and radiotherapy with no effective treatment. We tested the ability ofpalifermin (recombinant human keratinocyte growth factor) to decrease oral mucosal injury induced by cytotoxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a772fc914ec4014870df547ba392593
Autor:
Frederick M. Schnell, Stephen Clarke, Alessandra Cesano, Lee S. Rosen, E Abdi, Ian D. Davis, John Zalcberg, John Gutheil, Mon Gy Chen, Urte Gayko
Publikováno v:
Journal of Clinical Oncology. 26:1386-1387
We would like to address questions raised in Dr Haines’ Letter to the Editor published July 1, 2007,1 regarding the study, “Palifermin reduces the incidence of mucositis in patients with metastatic colorectal cancer treated with fluorouracil-base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::897cbfafb2477bffbbcab21a547df435
https://doi.org/10.1200/jco.2007.15.4492
https://doi.org/10.1200/jco.2007.15.4492