Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Momtaz E. M. Bakheet"'
Publikováno v:
Journal of Chemical Crystallography. 53:38-49
Autor:
Ashraf A. Aly, Essmat M. El-Sheref, Momtaz E. M. Bakheet, Aboul-Fetouh E. Mourad, Stefan Bräse, Martin Nieger
Publikováno v:
Chemical Papers. 73:27-37
In this investigation an efficient synthesis of 2,3-bis-(4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)succinic acid derivatives was achieved by one-pot reaction of one equivalent of aromatic amines with two equivalents of diethyl malonate in diphenyl eth
Autor:
Stefan Bräse, Ashraf A. Aly, Alan B. Brown, Momtaz E. M. Bakheet, Aboul-Fetouh E. Mourad, Essmat M. El-Sheref
Publikováno v:
Chemical Papers. 72:181-190
Reaction of equimolar amounts of 2,4(1H,3H)-quinolinediones and diethyl acetylenedicarboxylate in absolute ethanol, containing catalytic triethylamine, gave ethyl 5,6-dihydro-2,5-dioxo-6,9-disubstituted-2H-pyrano[3,2-c]quinoline-4-carboxylates in goo
Autor:
Momtaz E. M. Bakheet, Essmat M. El-Sheref, Stefan Bräse, Ashraf A. Aly, Aboul-Fetouh E. Mourad
Publikováno v:
Molecular diversity. 24(2)
The interesting pharmaceutical and biological activities of 4-hydroxy-2-quinolones make them valuable in drug research and development. Hence, many publications have recently dealt with their synthetic analogous and the synthesis of their heteroannel
Autor:
Momtaz E. M. Bakheet, Mai A.E. Mourad, Mahmoud A. A. Ibrahim, Martin Nieger, Essmat M. El-Sheref, Tamer S. Kaoud, Boyan K. Garvalov, Ashraf A. Aly, Kevin N. Dalby, Stefan Bräse
Approximately 60% of human cancers exhibit enhanced activity of ERK1 and ERK2, reflecting their multiple roles in tumor initiation and progression. Acquired drug resistance, especially mechanisms associated with the reactivation of the MAPK (RAF/MEK/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cecdc0336ec22edd17175f0dbd110ad7
http://hdl.handle.net/10138/325574
http://hdl.handle.net/10138/325574
Autor:
Mai A.E. Mourad, Ashraf A. Aly, Martin Nieger, Essmat M. El-Sheref, Stefan Bräse, Momtaz E. M. Bakheet, Mahmoud A. A. Ibrahim, Alan B. Brown
Two novel series of N-2,3-bis(6-substituted-4-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)naphthalene-1,4-diones 3a-d and substituted N-(methyl/ethyl)bisquinolinone triethyl-ammonium salts 4e,f were successfully synthesized. The synthesized compounds were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1e95795a710742299b955f09b76c822
http://hdl.handle.net/10138/322150
http://hdl.handle.net/10138/322150
Autor:
Momtaz E. M. Bakheet, Alan B. Brown, Martin Nieger, Aboul-Fetouh E. Mourad, Stefan Bräse, Essmat M. El-Sheref, Ashraf A. Aly
Quinoline-2,4-diones reacted with 2-(2-oxo-1,2-dihydroindol-3-ylidene)malononitrile in pyridine to give 2'-amino-2,5'-dioxo-5',6'-dihydrospiro(indoline-3,4'-pyrano[3,2-c]quinoline)-3'-carbonitriles in good to excellent yields. The structures of all n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775dfacb2ecc9bc88ebd58ec1fe3e941
http://hdl.handle.net/10138/309240
http://hdl.handle.net/10138/309240