Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Momotaro Asada"'
Autor:
Haruo Sugiyama, Kotomi Kawasaki, Yusuke Oji, Hiroko Nakajima, Naoki Hosen, Hiroyasu Ogawa, Tomoki Masuda, Yoshihiro Oka, Ichiro Kawase, Tamotsu Yamagami, Sumiyuki Nishida, Yukiko Kishimoto, Momotaro Asada, Sei-ichi Yusa, Keisuke Kanato, Akihiro Tsuboi, Masaki Murakami, Manabu Kawakami, Fritz Melchers, Toru Miyazaki, Hanfen Li
Publikováno v:
International Journal of Hematology. 77:463-470
In the thymi of WT1-transgenic (Tg) mice with the 17AA+/KTS- spliced form of the Wilms tumor gene WT1 driven by the lck promoter, the frequencies of CD4-CD8- double-negative (DN) thymocytes were significantly increased relative to those in normal lit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d46e0c5905c87f8fa05ce0ab002b6c3
https://doi.org/10.1007/bf02986614
https://doi.org/10.1007/bf02986614
Autor:
Akihiro Tsuboi, Naoki Hosen, Hiroko Nakajima, Yoshihiro Oka, Tatsuya Fujioka, Keiko Udaka, Fei Wu, Sumiyuki Nishida, Momotaro Asada, Yuki Taniguchi, Masaki Murakami, Akio Hiraki, Ichiro Kawase, Akiko Nakano, Yusuke Oji, Haruo Sugiyama, Manabu Kawakami, Masaki Yasukawa, Tomoki Masuda, Hiroyasu Ogawa
Publikováno v:
Cancer Immunology, Immunotherapy. 51:614-620
The Wilms' tumor gene WT1 is overexpressed in most types of leukemias and various kinds of solid tumors, including lung and breast cancer, and participates in leukemogenesis and tumorigenesis. WT1 protein has been reported to be a promising tumor ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8949708b132f409a1249a72c9d7aab58
https://doi.org/10.1007/s00262-002-0328-9
https://doi.org/10.1007/s00262-002-0328-9
Autor:
Seiji Hayashi, Eigo Takahashi, Akihiro Tsuboi, Hiroyasu Ogawa, Shinichiro Miyoshi, Momotaro Asada, Katsuyuki Aozasa, Hajime Maeda, Haruo Sugiyama, Ichiro Kawase, Masaki Murakami, Mari Motomura, Shin-ichi Nakatsuka, Keisuke Kanato, Kazuhiro Ikegame, Yoko Nakano, Masayuki Yao, Yusuke Oji, Eui Ho Kim, Hiroya Tamaki, Naoki Hosen, Hirohisa Hirabayashi, Yoshihiro Oka, Manabu Kawakami, Yasushi Shintani, Tatsuya Fujioka
Publikováno v:
International Journal of Cancer. 100:297-303
Expression of the Wilms' tumor gene WT1 in de novo lung cancer was examined using quantitative real-time RT-PCR and immunohistochemistry. Overexpression of the WT1 gene was detected by RT-PCR in 54/56 (96%) de novo non-small cell lung cancers examine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::445abd57a25760a4a2053aba9f59785b
https://doi.org/10.1002/ijc.10476
https://doi.org/10.1002/ijc.10476
Autor:
Haruo Sugiyama, Yusuke Oji, Tatsuya Fujioka, Hiroya Tamaki, Eui Ho Kim, Masaki Murakami, Hitoshi Minamiguchi, Mari Motomura, Tomoki Masuda, Yoshiaki Sonoda, Takafumi Kimura, Momotaro Asada, Yoshihiro Oka, Toshihiro Soma, Keisuke Kanato, Naoki Hosen, Manabu Kawakami, Akihiro Tsuboi, Hiroyasu Ogawa
Publikováno v:
British Journal of Haematology. 116:409-420
The Wilms' tumour gene, WT1, is expressed at high levels in leukaemia cells and plays an important role in leukaemogenesis. WT1 is also expressed in human normal CD34+ bone marrow (BM) cells at about 100 times lower levels than in leukaemia cells. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::969ec33453f323d11384949f3ef6dbc5
https://doi.org/10.1046/j.1365-2141.2002.03261.x
https://doi.org/10.1046/j.1365-2141.2002.03261.x
Autor:
Yusuke Oji, Tadamitsu Kishimoto, Haruo Sugiyama, Hiroya Tamaki, Toshihiro Soma, Yoshihiro Oka, Eui Ho Kim, Hiroh Saji, Olga A. Elisseeva, Kazuyuki Ueda, Momotaro Asada, Hiroyasu Ogawa, Hanfen Li, Etsuko Maruya, Akihiro Tsuboi, Keiko Udaka
Publikováno v:
Immunogenetics. 51:99-107
The product of the Wilms' tumor gene WT1 is a transcription factor overexpressed not only in leukemic blast cells of almost all patients with acute myeloid leukemia, acute lymphoid leukemia, and chronic myeloid leukemia, but also in various types of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aa016f1f0028d7ddd80ec465a3e3031
https://doi.org/10.1007/s002510050018
https://doi.org/10.1007/s002510050018
Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway
Autor:
Haruo Sugiyama, Yoshihiro Oka, Toshiaki Shirakata, Sumiyuki Nishida, Sayaka Aoyagi, Ken Ito, Tanyarat Jomgeow, Y Kanai, Yoshihide Tsujimoto, Hiroya Tamaki, Manabu Kawakami, Naoko Tatsumi, Momotaro Asada, Yoko Nakano, Yusuke Oji, Shigeomi Shimizu, Akihiro Tsuboi, Tsutomu Nakazawa, Nao Sakaguchi
Publikováno v:
Oncogene. 25(30)
The WT1 gene is overexpressed in human primary leukemia and a wide variety of solid cancers. The WT1 gene is alternatively spliced at two sites, yielding four isoforms: 17AA(+)KTS(+), 17AA(+)KTS(-), 17AA(-)KTS(+), and 17AA(-)KTS(-). Here, we showed t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30fbf702002fe7ec66ac7bb16d17952a
https://pubmed.ncbi.nlm.nih.gov/16518414
https://pubmed.ncbi.nlm.nih.gov/16518414
Autor:
Momotaro Asada, Tsutomu Nakazawa, Haruo Sugiyama, Yuki Taniguchi, Keisuke Kanato, Yoshio Oka, Sumiyuki Nishida, Kazuhiro Ikegame, Naoki Hosen, Akio Tsuboi, Yusuke Oji, Masashi Yanagihara, Toshiaki Shirakata, Ichiro Kawase, Manabu Kawakami, Tomoki Masuda, Hiroyasu Ogawa
Publikováno v:
Leukemia. 18(3)
Leukemia-specific promoters and enhancers for gene therapy had never been reported. Since the Wilms' tumor gene WT1 is overexpressed in almost all types of leukemia, WT1 is an ideal target of leukemia-specific therapy. To explore the possibility of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef73535c6fe0323c9da19e4594ea81d0
https://pubmed.ncbi.nlm.nih.gov/14737070
https://pubmed.ncbi.nlm.nih.gov/14737070
Autor:
Hideki Yoshikawa, Shin-ichi Nakatsuka, Momotaro Asada, Noriyuki Tamai, Katsuyuki Aozasa, Naoki Hosen, Haruo Sugiyama, Yoko Nakano, Norifumi Naka, Akira Myoui, Yusuke Oji, Satoko Koga, Yasuhiko Tomita, Takafumi Ueda, Sakie Abeno, Ai Ikeba, Eigo Takahashi
Publikováno v:
Cancer science. 94(3)
The expression levels of the Wilms' tumor gene WT1 were examined in 36 cases of various types of human bone and soft-tissue sarcomas using quantitative real-time reverse transcription-polymerase chain reaction (RT-PCR). They included 12 malignant fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ec0a631d98376a105092b86ff0d5cb5
https://pubmed.ncbi.nlm.nih.gov/12824921
https://pubmed.ncbi.nlm.nih.gov/12824921
Autor:
Naoki, Hosen, Yoshiaki, Sonoda, Yusuke, Oji, Takafumi, Kimura, Hitoshi, Minamiguchi, Hiroya, Tamaki, Manabu, Kawakami, Momotaro, Asada, Keisuke, Kanato, Mari, Motomura, Masaki, Murakami, Tatsuya, Fujioka, Tomoki, Masuda, Eui Ho, Kim, Akihiro, Tsuboi, Yoshihiro, Oka, Toshihiro, Soma, Hiroyasu, Ogawa, Haruo, Sugiyama
Publikováno v:
British journal of haematology. 116(2)
The Wilms' tumour gene, WT1, is expressed at high levels in leukaemia cells and plays an important role in leukaemogenesis. WT1 is also expressed in human normal CD34+ bone marrow (BM) cells at about 100 times lower levels than in leukaemia cells. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aa26a9d87c87e1f888447d2d433b7194
https://pubmed.ncbi.nlm.nih.gov/11841446
https://pubmed.ncbi.nlm.nih.gov/11841446
Autor:
Haruo Sugiyama, Eui Ho Kim, Tadamitsu Kishimoto, Akihiro Tsuboi, Hiroyasu Ogawa, Toshihiro Soma, Manabu Kawakami, Hiroya Tamaki, Yusuke Oji, Momotaro Asada, Toyoshi Tatekawa, Yoshihiro Oka
Publikováno v:
Japanese Journal of Cancer Research : Gann
To determine the role of the Wilms' tumor gene WT1 in tumorigenesis of solid tumors, expression of the WT1 gene was examined in 34 solid tumor cell lines (four gastric cancer cell lines, five colon cancer cell lines, 15 lung cancer cell lines, four b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565546e4de5d16a40930f3aa5d45fcd1
https://pubmed.ncbi.nlm.nih.gov/10189890
https://pubmed.ncbi.nlm.nih.gov/10189890