Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Momomi Tsugane"'
Autor:
Keisuke Taniguchi, Hiroaki Konishi, Akiko Yoshinaga, Momomi Tsugane, Hiroyuki Takahashi, Fukiko Nishisaka, Yoshiyuki Shishido, Akira Asai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Signal transducer and activator of transcription 3 (STAT3) plays a critical role in regulating cell growth, survival, and metastasis. STAT3 signaling is constitutively activated in various types of hematologic or solid malignancies. YHO-1701
Externí odkaz:
https://doaj.org/article/b2fd71e3e98c45489e828ff9edfd8062
Autor:
Keisuke Taniguchi, Tomo Suzuki, Tomomi Okamura, Akinobu Kurita, Gou Nohara, Satoru Ishii, Shoichi Kado, Akimitsu Takagi, Momomi Tsugane, Yoshiyuki Shishido
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Metastatic brain tumors are regarded as the most advanced stage of certain types of cancer; however, chemotherapy has played a limited role in the treatment of brain metastases. Here, we established murine models of brain metastasis using cell lines
Externí odkaz:
https://doaj.org/article/39157eec5a8c4744ab579f8c951d9381
Autor:
Yoshiyuki Shishido, Akimitsu Takagi, Akinobu Kurita, Tomo Suzuki, Tomomi Okamura, Gou Nohara, Shoichi Kado, Keisuke Taniguchi, Satoru Ishii, Momomi Tsugane
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 11 (2021)
Frontiers in Oncology, Vol 11 (2021)
Metastatic brain tumors are regarded as the most advanced stage of certain types of cancer; however, chemotherapy has played a limited role in the treatment of brain metastases. Here, we established murine models of brain metastasis using cell lines
Publikováno v:
Journal of Cellular Signaling. 2
Autor:
Akinobu Kurita, Yoshiyuki Shishido, Hiroyuki Takahashi, Genya Hirata, Keisuke Taniguchi, Fukiko Nishisaka, Akira Asai, Naoyuki Asakawa, Akimitsu Takagi, Momomi Tsugane, Naohisa Ogo
Publikováno v:
Cancer Science
The signal transducer and activator of transcription 3 (STAT3) signaling pathway is a key mediator of cancer cell proliferation, survival and invasion. Aberrant STAT3 has been demonstrated in various malignant cancers. YHO‐1701 is a novel quinoline
Autor:
Keiko Hiyama, Yusuke Sotomaru, Youhei Nishimura, Eiso Hiyama, Keiji Tanimoto, Ikuko Fukuba, Masahiko Nishiyama, Momomi Tsugane
Publikováno v:
Experimental Lung Research. 34(7):373-390
Regulation mechanism of lung fibroblast proliferation remains unknown. To elucidate the key molecules in it, the authors here established mortal and immortal nontransformed lung fibroblast cell line/strains with elongated life span by telomerase reve
Autor:
Akinobu Watanabe, Hiroshi Kodaira, Momomi Tsugane, Hiroaki Konishi, Yu Inutake, Hiroyuki Takahashi, Akimitsu Takagi, Takeshi Matsuzaki, Keisuke Taniguchi
Publikováno v:
Cancer Research. 74:5534-5534
Background: Accumulating evidence reveals effectiveness of histone deacetylase (HDAC) inhibition in various types of cancer, and resminostat is a novel and oral HDAC inhibitor. In this study, we investigated the preclinical activity of resminostat in
Autor:
Ken-ichi Sata, Satoru Ishii, Hiroshi Kodaira, Momomi Tsugane, Hiroaki Konishi, Akimitsu Takagi, Takeshi Matsuzaki
Publikováno v:
Cancer Research. 73:3994-3994
Background: Perifosine is an oral anticancer compound that inhibits the PH-domain of AKT, which is frequently activated in human cancers including gastric cancer. In this study, the mode of action of perifosine, especially in association with mTOR, a