Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Momoko Ando"'
Publikováno v:
Journal of the Society of Materials Science, Japan. 70:547-553
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e11517cd4f4c8e423cb453f94afaecfa
https://doi.org/10.2472/jsms.70.547
https://doi.org/10.2472/jsms.70.547
Autor:
Mitsuteru Numazawa, Yasuko Hayata, Takako Tominaga, Momoko Ando, Akiko Yoshimura, Yoko Watari
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 96:51-58
Aromatase, which is responsible for the conversion of androgens to estrogens, is a potential therapeutic target for the selective lowering of estrogen levels in patients with estrogen-dependent breast cancer. To develop a novel class of aromatase inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97601f3c48c907dfc12c2a0c5e487fc
https://doi.org/10.1016/j.jsbmb.2005.01.028
https://doi.org/10.1016/j.jsbmb.2005.01.028
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 82:65-73
To gain insight into the catalytic function of aromatase, we studied aromatization of a series of 6α- and 6β-ether-substituted (methoxy, ethoxy, and n -butoxy) androst-4-ene-3,17-dione (AD) steroids ( 1 and 2 ) and their androsta-1,4-diene-3,17-dio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76828ff78520575fed918951715c186f
https://doi.org/10.1016/s0960-0760(02)00148-6
https://doi.org/10.1016/s0960-0760(02)00148-6
Publikováno v:
ChemInform. 33
4β,19-Dihydroxyandrost-5-en-17-one (6) is an excellent competitive inhibitor of estrogen synthetase (aromatase). Alternate, improved synthesis of this inhibitor was established. Treatment of 19-(tert-butyldimethylsilyloxy)androst-4-en-17-one (8) wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f6e79c9d355b4c8223c2ac0a7a83048
https://doi.org/10.1002/chin.200242209
https://doi.org/10.1002/chin.200242209