Discordant Genome Assemblies Drastically Alter the Interpretation of Single-Cell RNA Sequencing Data Which Can Be Mitigated by a Novel Integration Method

Autor: Potts, HG, Lemieux, ME, Rice, ES, Warren, W, Choudhury, RP, Mommersteeg, MTM

Publikováno v: Cells; Volume 11; Issue 4; Pages: 608
Cells

Advances in sequencing and assembly technology have led to the creation of genome assemblies for a wide variety of non-model organisms. The rapid production and proliferation of updated, novel assembly versions can create vexing problems for research

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd2c5c3853418a92115cd25ce474367
https://doi.org/10.3390/cells11040608

The developmental origin of heart size and shape differences in Astyanax mexicanus populations

Autor: Tang, JLY, Guo, Y, Stockdale, WT, Rana, K, Killen, AC, Mommersteeg, MTM, Yamamoto, Y

Publikováno v: Developmental Biology

Regulation of heart size and shape is one of the least understood processes in developmental biology. We have for the first time analysed the hearts of Astyanax mexicanus and identified several differences in heart morphology between the surface (epi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::76d8f7db6c36c8fedf31d9bdef03f8fe

Extraordinary model systems for regeneration.

Autor: Accorsi A; University of California Davis, Department of Molecular and Cellular Biology, Davis, CA 95616, USA., Guo L; Department of Molecular & Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA.; Institute of Gerontology, Geriatrics Center, University of Michigan, Ann Arbor, MI 48109, USA., Marshall WF; Deptartment of Biochemistry & Biophysics, University of California, San Francisco, 600 16th Street, San Francisco, CA 94158, USA., Mommersteeg MTM; Institute of Developmental & Regenerative Medicine (IDRM), Department of Physiology, Anatomy & Genetics, IMS-Tetsuya Nakamura Building, Old Road Campus, Roosevelt Drive, Headington, Oxford OX3 7TY, UK., Nakajima YI; Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

Publikováno v: Development (Cambridge, England) [Development] 2024 Oct 15; Vol. 151 (20). Date of Electronic Publication: 2024 Jul 15.

A chromosome-level genome of Astyanax mexicanus surface fish for comparing population-specific genetic differences contributing to trait evolution.

Autor: Warren WC; Department of Animal Sciences, Institute for Data Science and Informatics, Bond Life Sciences Center, University of Missouri, Columbia, MO, USA. wwarren@genome.wustl.edu.; Department of Surgery, Institute for Data Science and Informatics, Bond Life Sciences Center, University of Missouri, Columbia, MO, USA. wwarren@genome.wustl.edu., Boggs TE; Department of Biological Sciences, University of Cincinnati, Cincinnati, OH, USA., Borowsky R; Department of Biology, New York University, New York, NY, USA., Carlson BM; Department of Biological Sciences, Northern Kentucky University, Highland Heights, KY, USA., Ferrufino E; Harriet L. Wilkes Honors College, Florida Atlantic University, Jupiter, FL, USA., Gross JB; Department of Biological Sciences, University of Cincinnati, Cincinnati, OH, USA., Hillier L; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Hu Z; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Keene AC; Department of Biological Sciences, Florida Atlantic University, Jupiter, FL, USA., Kenzior A; Stowers Institute for Medical Research, Kansas City, MO, USA., Kowalko JE; Harriet L. Wilkes Honors College, Florida Atlantic University, Jupiter, FL, USA., Tomlinson C; McDonnell Genome Institute, Washington University, St Louis, MO, USA., Kremitzki M; McDonnell Genome Institute, Washington University, St Louis, MO, USA., Lemieux ME; Bioinfo, Plantagenet, ON, Canada., Graves-Lindsay T; McDonnell Genome Institute, Washington University, St Louis, MO, USA., McGaugh SE; Department of Ecology, Evolution, and Behavior, University of Minnesota, Saint Paul, MN, USA., Miller JT; Department of Ecology, Evolution, and Behavior, University of Minnesota, Saint Paul, MN, USA., Mommersteeg MTM; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Moran RL; Department of Ecology, Evolution, and Behavior, University of Minnesota, Saint Paul, MN, USA., Peuß R; Stowers Institute for Medical Research, Kansas City, MO, USA.; Institute for Evolution and Biodiversity, University of Münster, Münster, Germany., Rice ES; Bond Life Sciences Center, University of Missouri, Columbia, MO, USA., Riddle MR; Genetics Department, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.; Department of Biology, University of Nevada, Reno, NV, USA., Sifuentes-Romero I; Harriet L. Wilkes Honors College, Florida Atlantic University, Jupiter, FL, USA., Stanhope BA; Harriet L. Wilkes Honors College, Florida Atlantic University, Jupiter, FL, USA.; Department of Biological Sciences, Florida Atlantic University, Jupiter, FL, USA., Tabin CJ; Genetics Department, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Thakur S; Harriet L. Wilkes Honors College, Florida Atlantic University, Jupiter, FL, USA., Yamamoto Y; Department of Cell and Developmental Biology, University College London, London, UK., Rohner N; Stowers Institute for Medical Research, Kansas City, MO, USA. nro@stowers.org.; Department of Molecular & Integrative Physiology, KU Medical Center, Kansas City, KS, USA. nro@stowers.org.

Publikováno v: Nature communications [Nat Commun] 2021 Mar 04; Vol. 12 (1), pp. 1447. Date of Electronic Publication: 2021 Mar 04.

T-box transcription factor 3 governs a transcriptional program for the function of the mouse atrioventricular conduction system.

Autor: Mohan RA; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.; Department of Clinical and Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., Bosada FM; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., van Weerd JH; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., van Duijvenboden K; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., Wang J; Department of Clinical and Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., Mommersteeg MTM; Burdon Sanderson Cardiac Science Centre, Department of Physiology, Anatomy & Genetics, University of Oxford, Oxford OX1 3PT, United Kingdom., Hooijkaas IB; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., Wakker V; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., de Gier-de Vries C; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., Coronel R; Department of Clinical and Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., Boink GJJ; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.; Department of Clinical and Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., Bakkers J; Hubrecht Institute and University Medical Center Utrecht, 3584 CT Utrecht, the Netherlands., Barnett P; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., Boukens BJ; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.; Department of Clinical and Experimental Cardiology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands., Christoffels VM; Department of Medical Biology, Amsterdam University Medical Centers, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands; v.m.christoffels@amsterdamumc.nl.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Aug 04; Vol. 117 (31), pp. 18617-18626. Date of Electronic Publication: 2020 Jul 16.